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ZFAND6 (zinc finger AN1-type containing 6)

Identity

Alias (NCBI)AWP1
ZA20D3
ZFAND5B
HGNC (Hugo) ZFAND6
HGNC Alias symbZFAND5B
AWP1
HGNC Alias nameprotein associated with PRK1
HGNC Previous nameZA20D3
HGNC Previous namezinc finger, A20 domain containing 3
 zinc finger, AN1-type domain 6
LocusID (NCBI) 54469
Atlas_Id 52595
Location 15q25.1  [Link to chromosome band 15q25]
Location_base_pair Starts at 80059676 and ends at 80138393 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DGKB (7p21.2) / ZFAND6 (15q25.1)USP48 (1p36.12) / ZFAND6 (15q25.1)ZFAND6 (15q25.1) / PSMB1 (6q27)
ZFAND6 (15q25.1) / ZFAND6 (15q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZFAND6   30164
Cards
Entrez_Gene (NCBI)ZFAND6    zinc finger AN1-type containing 6
AliasesAWP1; ZA20D3; ZFAND5B
GeneCards (Weizmann)ZFAND6
Ensembl hg19 (Hinxton)ENSG00000086666 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000086666 [Gene_View]  ENSG00000086666 [Sequence]  chr15:80059676-80138393 [Contig_View]  ZFAND6 [Vega]
ICGC DataPortalENSG00000086666
TCGA cBioPortalZFAND6
AceView (NCBI)ZFAND6
Genatlas (Paris)ZFAND6
SOURCE (Princeton)ZFAND6
Genetics Home Reference (NIH)ZFAND6
Genomic and cartography
GoldenPath hg38 (UCSC)ZFAND6  -     chr15:80059676-80138393 +  15q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFAND6  -     15q25.1   [Description]    (hg19-Feb_2009)
GoldenPathZFAND6 - 15q25.1 [CytoView hg19]  ZFAND6 - 15q25.1 [CytoView hg38]
ImmunoBaseENSG00000086666
Genome Data Viewer NCBIZFAND6 [Mapview hg19]  
OMIM610183   
Gene and transcription
Genbank (Entrez)AF061739 AF261138 AJ251095 AK055881 AK312646
RefSeq transcript (Entrez)NM_001242911 NM_001242912 NM_001242913 NM_001242914 NM_001242915 NM_001242916 NM_001242917 NM_001242918 NM_001242919 NM_019006
Consensus coding sequences : CCDS (NCBI)ZFAND6
Gene ExpressionZFAND6 [ NCBI-GEO ]   ZFAND6 [ EBI - ARRAY_EXPRESS ]   ZFAND6 [ SEEK ]   ZFAND6 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFAND6 [ Firebrowse - Broad ]
GenevisibleExpression of ZFAND6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54469
GTEX Portal (Tissue expression)ZFAND6
Human Protein AtlasENSG00000086666-ZFAND6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6FIF0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6FIF0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6FIF0
PhosPhoSitePlusQ6FIF0
Domaine pattern : Prosite (Expaxy)ZF_A20 (PS51036)    ZF_AN1 (PS51039)   
Domains : Interpro (EBI)AN1-like_Znf    Znf_A20    Znf_AN1   
Domain families : Pfam (Sanger)zf-A20 (PF01754)    zf-AN1 (PF01428)   
Domain families : Pfam (NCBI)pfam01754    pfam01428   
Domain families : Smart (EMBL)ZnF_A20 (SM00259)  ZnF_AN1 (SM00154)  
Conserved Domain (NCBI)ZFAND6
SuperfamilyQ6FIF0
AlphaFold pdb e-kbQ6FIF0   
Human Protein Atlas [tissue]ENSG00000086666-ZFAND6 [tissue]
HPRD18314
Protein Interaction databases
DIP (DOE-UCLA)Q6FIF0
IntAct (EBI)Q6FIF0
BioGRIDZFAND6
STRING (EMBL)ZFAND6
ZODIACZFAND6
Ontologies - Pathways
QuickGOQ6FIF0
Ontology : AmiGOmolecular_function  DNA binding  protein binding  cellular_component  cytosol  protein targeting to peroxisome  protein targeting to peroxisome  apoptotic process  protein localization  zinc ion binding  polyubiquitin modification-dependent protein binding  polyubiquitin modification-dependent protein binding  negative regulation of apoptotic process  regulation of I-kappaB kinase/NF-kappaB signaling  cellular response to tumor necrosis factor  
Ontology : EGO-EBImolecular_function  DNA binding  protein binding  cellular_component  cytosol  protein targeting to peroxisome  protein targeting to peroxisome  apoptotic process  protein localization  zinc ion binding  polyubiquitin modification-dependent protein binding  polyubiquitin modification-dependent protein binding  negative regulation of apoptotic process  regulation of I-kappaB kinase/NF-kappaB signaling  cellular response to tumor necrosis factor  
NDEx NetworkZFAND6
Atlas of Cancer Signalling NetworkZFAND6
Wikipedia pathwaysZFAND6
Orthology - Evolution
OrthoDB54469
GeneTree (enSembl)ENSG00000086666
Phylogenetic Trees/Animal Genes : TreeFamZFAND6
Homologs : HomoloGeneZFAND6
Homology/Alignments : Family Browser (UCSC)ZFAND6
Gene fusions - Rearrangements
Fusion : QuiverZFAND6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFAND6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFAND6
dbVarZFAND6
ClinVarZFAND6
MonarchZFAND6
1000_GenomesZFAND6 
Exome Variant ServerZFAND6
GNOMAD BrowserENSG00000086666
Varsome BrowserZFAND6
ACMGZFAND6 variants
VarityQ6FIF0
Genomic Variants (DGV)ZFAND6 [DGVbeta]
DECIPHERZFAND6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFAND6 
Mutations
ICGC Data PortalZFAND6 
TCGA Data PortalZFAND6 
Broad Tumor PortalZFAND6
OASIS PortalZFAND6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFAND6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZFAND6
Mutations and Diseases : HGMDZFAND6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZFAND6
DgiDB (Drug Gene Interaction Database)ZFAND6
DoCM (Curated mutations)ZFAND6
CIViC (Clinical Interpretations of Variants in Cancer)ZFAND6
Cancer3DZFAND6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610183   
Orphanet
DisGeNETZFAND6
MedgenZFAND6
Genetic Testing Registry ZFAND6
NextProtQ6FIF0 [Medical]
GENETestsZFAND6
Target ValidationZFAND6
Huge Navigator ZFAND6 [HugePedia]
ClinGenZFAND6
Clinical trials, drugs, therapy
MyCancerGenomeZFAND6
Protein Interactions : CTDZFAND6
Pharm GKB GenePA134883256
PharosQ6FIF0
Clinical trialZFAND6
Miscellaneous
canSAR (ICR)ZFAND6
HarmonizomeZFAND6
DataMed IndexZFAND6
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZFAND6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:56 CEST 2021

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