Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZFHX2 (zinc finger homeobox 2)

Identity

Alias_namesZNF409
zinc finger protein 409
Alias_symbol (synonym)KIAA1762
KIAA1056
ZFH-5
Other alias
HGNC (Hugo) ZFHX2
LocusID (NCBI) 85446
Atlas_Id 75929
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 23520855 and ends at 23551649 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZFHX2   20152
Cards
Entrez_Gene (NCBI)ZFHX2  85446  zinc finger homeobox 2
AliasesZFH-5; ZNF409
GeneCards (Weizmann)ZFHX2
Ensembl hg19 (Hinxton)ENSG00000136367 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136367 [Gene_View]  chr14:23520855-23551649 [Contig_View]  ZFHX2 [Vega]
ICGC DataPortalENSG00000136367
TCGA cBioPortalZFHX2
AceView (NCBI)ZFHX2
Genatlas (Paris)ZFHX2
WikiGenes85446
SOURCE (Princeton)ZFHX2
Genetics Home Reference (NIH)ZFHX2
Genomic and cartography
GoldenPath hg38 (UCSC)ZFHX2  -     chr14:23520855-23551649 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFHX2  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblZFHX2 - 14q11.2 [CytoView hg19]  ZFHX2 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIZFHX2 [Mapview hg19]  ZFHX2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB028979 AB051549 AI093184 BC131533 BC144336
RefSeq transcript (Entrez)NM_033400
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFHX2
Cluster EST : UnigeneHs.508937 [ NCBI ]
CGAP (NCI)Hs.508937
Alternative Splicing GalleryENSG00000136367
Gene ExpressionZFHX2 [ NCBI-GEO ]   ZFHX2 [ EBI - ARRAY_EXPRESS ]   ZFHX2 [ SEEK ]   ZFHX2 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFHX2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85446
GTEX Portal (Tissue expression)ZFHX2
Human Protein AtlasENSG00000136367-ZFHX2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0A1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0A1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0A1
Splice isoforms : SwissVarQ9C0A1
PhosPhoSitePlusQ9C0A1
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    ZFHX2    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd    Znf_U1   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  ZnF_C2H2 (SM00355)  ZnF_U1 (SM00451)  
Conserved Domain (NCBI)ZFHX2
DMDM Disease mutations85446
Blocks (Seattle)ZFHX2
SuperfamilyQ9C0A1
Human Protein Atlas [tissue]ENSG00000136367-ZFHX2 [tissue]
Peptide AtlasQ9C0A1
HPRD18318
IPIIPI00926149   IPI00007109   IPI01010327   IPI01025041   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0A1
IntAct (EBI)Q9C0A1
FunCoupENSG00000136367
BioGRIDZFHX2
STRING (EMBL)ZFHX2
ZODIACZFHX2
Ontologies - Pathways
QuickGOQ9C0A1
Ontology : AmiGOnucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  adult behavior  sequence-specific DNA binding  
Ontology : EGO-EBInucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  adult behavior  sequence-specific DNA binding  
NDEx NetworkZFHX2
Atlas of Cancer Signalling NetworkZFHX2
Wikipedia pathwaysZFHX2
Orthology - Evolution
OrthoDB85446
GeneTree (enSembl)ENSG00000136367
Phylogenetic Trees/Animal Genes : TreeFamZFHX2
HOVERGENQ9C0A1
HOGENOMQ9C0A1
Homologs : HomoloGeneZFHX2
Homology/Alignments : Family Browser (UCSC)ZFHX2
Gene fusions - Rearrangements
Fusion: Tumor Portal ZFHX2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFHX2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFHX2
dbVarZFHX2
ClinVarZFHX2
1000_GenomesZFHX2 
Exome Variant ServerZFHX2
ExAC (Exome Aggregation Consortium)ENSG00000136367
GNOMAD BrowserENSG00000136367
Genetic variants : HAPMAP85446
Genomic Variants (DGV)ZFHX2 [DGVbeta]
DECIPHERZFHX2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFHX2 
Mutations
ICGC Data PortalZFHX2 
TCGA Data PortalZFHX2 
Broad Tumor PortalZFHX2
OASIS PortalZFHX2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFHX2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFHX2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFHX2
DgiDB (Drug Gene Interaction Database)ZFHX2
DoCM (Curated mutations)ZFHX2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFHX2 (select a term)
intoGenZFHX2
Cancer3DZFHX2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZFHX2
Genetic Testing Registry ZFHX2
NextProtQ9C0A1 [Medical]
TSGene85446
GENETestsZFHX2
Target ValidationZFHX2
Huge Navigator ZFHX2 [HugePedia]
snp3D : Map Gene to Disease85446
BioCentury BCIQZFHX2
ClinGenZFHX2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85446
Chemical/Pharm GKB GenePA134951324
Clinical trialZFHX2
Miscellaneous
canSAR (ICR)ZFHX2 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFHX2
EVEXZFHX2
GoPubMedZFHX2
iHOPZFHX2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:36:25 CET 2017

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