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ZFP42 (ZFP42 zinc finger protein)

Identity

Alias_nameszinc finger protein 42 homolog (mouse)
zinc finger protein 42
Alias_symbol (synonym)REX1
ZNF754
Other aliasREX-1
zfp-42
HGNC (Hugo) ZFP42
LocusID (NCBI) 132625
Atlas_Id 46472
Location 4q35.2  [Link to chromosome band 4q35]
Location_base_pair Starts at 187995771 and ends at 188005049 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZFP42   30949
Cards
Entrez_Gene (NCBI)ZFP42  132625  ZFP42 zinc finger protein
AliasesREX-1; REX1; ZNF754; zfp-42
GeneCards (Weizmann)ZFP42
Ensembl hg19 (Hinxton)ENSG00000179059 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179059 [Gene_View]  ENSG00000179059 [Sequence]  chr4:187995771-188005049 [Contig_View]  ZFP42 [Vega]
ICGC DataPortalENSG00000179059
TCGA cBioPortalZFP42
AceView (NCBI)ZFP42
Genatlas (Paris)ZFP42
WikiGenes132625
SOURCE (Princeton)ZFP42
Genetics Home Reference (NIH)ZFP42
Genomic and cartography
GoldenPath hg38 (UCSC)ZFP42  -     chr4:187995771-188005049 +  4q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFP42  -     4q35.2   [Description]    (hg19-Feb_2009)
EnsemblZFP42 - 4q35.2 [CytoView hg19]  ZFP42 - 4q35.2 [CytoView hg38]
Mapping of homologs : NCBIZFP42 [Mapview hg19]  ZFP42 [Mapview hg38]
OMIM614572   
Gene and transcription
Genbank (Entrez)AA641545 AF450454 AK056719 AY429593 BE301754
RefSeq transcript (Entrez)NM_001304358 NM_174900
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFP42
Cluster EST : UnigeneHs.335787 [ NCBI ]
CGAP (NCI)Hs.335787
Alternative Splicing GalleryENSG00000179059
Gene ExpressionZFP42 [ NCBI-GEO ]   ZFP42 [ EBI - ARRAY_EXPRESS ]   ZFP42 [ SEEK ]   ZFP42 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFP42 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)132625
GTEX Portal (Tissue expression)ZFP42
Human Protein AtlasENSG00000179059-ZFP42 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96MM3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96MM3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96MM3
Splice isoforms : SwissVarQ96MM3
PhosPhoSitePlusQ96MM3
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)YY-1-like    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZFP42
DMDM Disease mutations132625
Blocks (Seattle)ZFP42
SuperfamilyQ96MM3
Human Protein Atlas [tissue]ENSG00000179059-ZFP42 [tissue]
Peptide AtlasQ96MM3
HPRD15726
IPIIPI00292080   
Protein Interaction databases
DIP (DOE-UCLA)Q96MM3
IntAct (EBI)Q96MM3
FunCoupENSG00000179059
BioGRIDZFP42
STRING (EMBL)ZFP42
ZODIACZFP42
Ontologies - Pathways
QuickGOQ96MM3
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific  RNA polymerase II repressing transcription factor binding  DNA binding  DNA-binding transcription factor activity  nucleus  transcription factor complex  cytoplasm  male gonad development  female gonad development  PcG protein complex  sequence-specific DNA binding  metal ion binding  meiotic cell cycle  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nuclear chromatin  RNA polymerase II proximal promoter sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific  RNA polymerase II repressing transcription factor binding  DNA binding  DNA-binding transcription factor activity  nucleus  transcription factor complex  cytoplasm  male gonad development  female gonad development  PcG protein complex  sequence-specific DNA binding  metal ion binding  meiotic cell cycle  
NDEx NetworkZFP42
Atlas of Cancer Signalling NetworkZFP42
Wikipedia pathwaysZFP42
Orthology - Evolution
OrthoDB132625
GeneTree (enSembl)ENSG00000179059
Phylogenetic Trees/Animal Genes : TreeFamZFP42
HOVERGENQ96MM3
HOGENOMQ96MM3
Homologs : HomoloGeneZFP42
Homology/Alignments : Family Browser (UCSC)ZFP42
Gene fusions - Rearrangements
Fusion : QuiverZFP42
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFP42 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFP42
dbVarZFP42
ClinVarZFP42
1000_GenomesZFP42 
Exome Variant ServerZFP42
ExAC (Exome Aggregation Consortium)ENSG00000179059
GNOMAD BrowserENSG00000179059
Varsome BrowserZFP42
Genetic variants : HAPMAP132625
Genomic Variants (DGV)ZFP42 [DGVbeta]
DECIPHERZFP42 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFP42 
Mutations
ICGC Data PortalZFP42 
TCGA Data PortalZFP42 
Broad Tumor PortalZFP42
OASIS PortalZFP42 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFP42  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFP42
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFP42
DgiDB (Drug Gene Interaction Database)ZFP42
DoCM (Curated mutations)ZFP42 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFP42 (select a term)
intoGenZFP42
Cancer3DZFP42(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614572   
Orphanet
DisGeNETZFP42
MedgenZFP42
Genetic Testing Registry ZFP42
NextProtQ96MM3 [Medical]
TSGene132625
GENETestsZFP42
Target ValidationZFP42
Huge Navigator ZFP42 [HugePedia]
snp3D : Map Gene to Disease132625
BioCentury BCIQZFP42
ClinGenZFP42
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD132625
Chemical/Pharm GKB GenePA142670530
Clinical trialZFP42
Miscellaneous
canSAR (ICR)ZFP42 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFP42
EVEXZFP42
GoPubMedZFP42
iHOPZFP42
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:51:00 CET 2018

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