Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZFP57 (ZFP57 zinc finger protein)

Identity

Alias_namesC6orf40
chromosome 6 open reading frame 40
zinc finger protein 57 homolog (mouse)
Alias_symbol (synonym)ZNF698
bA145L22
bA145L22.2
Other aliasTNDM1
HGNC (Hugo) ZFP57
LocusID (NCBI) 346171
Atlas_Id 54980
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 29672392 and ends at 29677154 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CIC (19q13.2) / ZFP57 (6p22.1)CIC 19q13.2 / ZFP57 6p22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;19)(p22;q13) CIC/ZFP57


External links

Nomenclature
HGNC (Hugo)ZFP57   18791
Cards
Entrez_Gene (NCBI)ZFP57  346171  ZFP57 zinc finger protein
AliasesC6orf40; TNDM1; ZNF698; bA145L22; 
bA145L22.2
GeneCards (Weizmann)ZFP57
Ensembl hg19 (Hinxton)ENSG00000204644 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204644 [Gene_View]  ENSG00000204644 [Sequence]  chr6:29672392-29677154 [Contig_View]  ZFP57 [Vega]
ICGC DataPortalENSG00000204644
TCGA cBioPortalZFP57
AceView (NCBI)ZFP57
Genatlas (Paris)ZFP57
WikiGenes346171
SOURCE (Princeton)ZFP57
Genetics Home Reference (NIH)ZFP57
Genomic and cartography
GoldenPath hg38 (UCSC)ZFP57  -     chr6:29672392-29677154 -  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFP57  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblZFP57 - 6p22.1 [CytoView hg19]  ZFP57 - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIZFP57 [Mapview hg19]  ZFP57 [Mapview hg38]
OMIM601410   612192   
Gene and transcription
Genbank (Entrez)BC157878 BC171888
RefSeq transcript (Entrez)NM_001109809 NM_001366333
RefSeq genomic (Entrez)NC_000006 NG_013045 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)ZFP57
Cluster EST : UnigeneHs.156326 [ NCBI ]
CGAP (NCI)Hs.156326
Alternative Splicing GalleryENSG00000204644
Gene ExpressionZFP57 [ NCBI-GEO ]   ZFP57 [ EBI - ARRAY_EXPRESS ]   ZFP57 [ SEEK ]   ZFP57 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFP57 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)346171
GTEX Portal (Tissue expression)ZFP57
Human Protein AtlasENSG00000204644-ZFP57 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NU63   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NU63  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NU63
Splice isoforms : SwissVarQ9NU63
PhosPhoSitePlusQ9NU63
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)   
Domain families : Pfam (NCBI)pfam01352   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZFP57
DMDM Disease mutations346171
Blocks (Seattle)ZFP57
SuperfamilyQ9NU63
Human Protein Atlas [tissue]ENSG00000204644-ZFP57 [tissue]
Peptide AtlasQ9NU63
IPIIPI00642672   IPI00646777   IPI00923474   
Protein Interaction databases
DIP (DOE-UCLA)Q9NU63
IntAct (EBI)Q9NU63
FunCoupENSG00000204644
BioGRIDZFP57
STRING (EMBL)ZFP57
ZODIACZFP57
Ontologies - Pathways
QuickGOQ9NU63
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of gene expression by genetic imprinting  regulation of transcription by RNA polymerase II  DNA methylation involved in embryo development  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of gene expression by genetic imprinting  regulation of transcription by RNA polymerase II  DNA methylation involved in embryo development  metal ion binding  
NDEx NetworkZFP57
Atlas of Cancer Signalling NetworkZFP57
Wikipedia pathwaysZFP57
Orthology - Evolution
OrthoDB346171
GeneTree (enSembl)ENSG00000204644
Phylogenetic Trees/Animal Genes : TreeFamZFP57
HOVERGENQ9NU63
HOGENOMQ9NU63
Homologs : HomoloGeneZFP57
Homology/Alignments : Family Browser (UCSC)ZFP57
Gene fusions - Rearrangements
Fusion : MitelmanCIC/ZFP57 [19q13.2/6p22.1]  [t(6;19)(p22;q13)]  
Fusion PortalCIC 19q13.2 ZFP57 6p22.1 BRCA
Fusion : QuiverZFP57
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFP57 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFP57
dbVarZFP57
ClinVarZFP57
1000_GenomesZFP57 
Exome Variant ServerZFP57
ExAC (Exome Aggregation Consortium)ENSG00000204644
GNOMAD BrowserENSG00000204644
Varsome BrowserZFP57
Genetic variants : HAPMAP346171
Genomic Variants (DGV)ZFP57 [DGVbeta]
DECIPHERZFP57 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFP57 
Mutations
ICGC Data PortalZFP57 
TCGA Data PortalZFP57 
Broad Tumor PortalZFP57
OASIS PortalZFP57 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFP57  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFP57
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFP57
DgiDB (Drug Gene Interaction Database)ZFP57
DoCM (Curated mutations)ZFP57 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFP57 (select a term)
intoGenZFP57
Cancer3DZFP57(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601410    612192   
Orphanet14459   
DisGeNETZFP57
MedgenZFP57
Genetic Testing Registry ZFP57
NextProtQ9NU63 [Medical]
TSGene346171
GENETestsZFP57
Target ValidationZFP57
Huge Navigator ZFP57 [HugePedia]
snp3D : Map Gene to Disease346171
BioCentury BCIQZFP57
ClinGenZFP57
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD346171
Chemical/Pharm GKB GenePA134937821
Clinical trialZFP57
Miscellaneous
canSAR (ICR)ZFP57 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFP57
EVEXZFP57
GoPubMedZFP57
iHOPZFP57
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:51:01 CET 2018

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