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ZFP91 (ZFP91 zinc finger protein, atypical E3 ubiquitin ligase)

Identity

Alias (NCBI)DMS-8
DSM-8
DSM8
FKSG11
PZF
ZFP-91
ZNF757
HGNC (Hugo) ZFP91
HGNC Alias symbPZF
ZNF757
HGNC Previous namezinc finger protein homologous to Zfp91 in mouse
 zinc finger protein 91 homolog (mouse)
LocusID (NCBI) 80829
Atlas_Id 55499
Location 11q12.1  [Link to chromosome band 11q12]
Location_base_pair Starts at 58579063 and ends at 58621550 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADI1 (2p25.3) / ZFP91 (11q12.1)GGCX (2p11.2) / ZFP91 (11q12.1)NAPB (20p11.21) / ZFP91 (11q12.1)
NID2 (14q22.1) / ZFP91 (11q12.1)ZFP91 (11q12.1) / CNTF (11q12.1)ZFP91 (11q12.1) / LPXN (11q12.1)
ZFP91 (11q12.1) / NOX4 (11q14.3)ZFP91 (11q12.1) / RAB6A (11q13.4)ZFP91 (11q12.1) / ZFP91 (11q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZFP91   14983
Cards
Entrez_Gene (NCBI)ZFP91    ZFP91 zinc finger protein, atypical E3 ubiquitin ligase
AliasesDMS-8; DSM-8; DSM8; FKSG11; 
PZF; ZFP-91; ZNF757
GeneCards (Weizmann)ZFP91
Ensembl hg19 (Hinxton)ENSG00000186660 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186660 [Gene_View]  ENSG00000186660 [Sequence]  chr11:58579063-58621550 [Contig_View]  ZFP91 [Vega]
ICGC DataPortalENSG00000186660
TCGA cBioPortalZFP91
AceView (NCBI)ZFP91
Genatlas (Paris)ZFP91
SOURCE (Princeton)ZFP91
Genetics Home Reference (NIH)ZFP91
Genomic and cartography
GoldenPath hg38 (UCSC)ZFP91  -     chr11:58579063-58621550 +  11q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFP91  -     11q12.1   [Description]    (hg19-Feb_2009)
GoldenPathZFP91 - 11q12.1 [CytoView hg19]  ZFP91 - 11q12.1 [CytoView hg38]
ImmunoBaseENSG00000186660
Genome Data Viewer NCBIZFP91 [Mapview hg19]  
OMIM619289   
Gene and transcription
Genbank (Entrez)AB056107 AF305825 AF310246 AI687439 AJ270692
RefSeq transcript (Entrez)NM_001197051 NM_053023
Consensus coding sequences : CCDS (NCBI)ZFP91
Gene ExpressionZFP91 [ NCBI-GEO ]   ZFP91 [ EBI - ARRAY_EXPRESS ]   ZFP91 [ SEEK ]   ZFP91 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFP91 [ Firebrowse - Broad ]
GenevisibleExpression of ZFP91 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80829
GTEX Portal (Tissue expression)ZFP91
Human Protein AtlasENSG00000186660-ZFP91 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JP5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JP5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JP5
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ96JP5
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZFP91
PDB (RSDB)2M9A   
PDB Europe2M9A   
PDB (PDBSum)2M9A   
PDB (IMB)2M9A   
Structural Biology KnowledgeBase2M9A   
SCOP (Structural Classification of Proteins)2M9A   
CATH (Classification of proteins structures)2M9A   
SuperfamilyQ96JP5
AlphaFold pdb e-kbQ96JP5   
Human Protein Atlas [tissue]ENSG00000186660-ZFP91 [tissue]
HPRD11700
Protein Interaction databases
DIP (DOE-UCLA)Q96JP5
IntAct (EBI)Q96JP5
BioGRIDZFP91
STRING (EMBL)ZFP91
ZODIACZFP91
Ontologies - Pathways
QuickGOQ96JP5
Ontology : AmiGOubiquitin-protein transferase activity  nucleus  nucleoplasm  nucleolus  regulation of transcription by RNA polymerase II  activation of NF-kappaB-inducing kinase activity  metal ion binding  protein K63-linked ubiquitination  
Ontology : EGO-EBIubiquitin-protein transferase activity  nucleus  nucleoplasm  nucleolus  regulation of transcription by RNA polymerase II  activation of NF-kappaB-inducing kinase activity  metal ion binding  protein K63-linked ubiquitination  
NDEx NetworkZFP91
Atlas of Cancer Signalling NetworkZFP91
Wikipedia pathwaysZFP91
Orthology - Evolution
OrthoDB80829
GeneTree (enSembl)ENSG00000186660
Phylogenetic Trees/Animal Genes : TreeFamZFP91
Homologs : HomoloGeneZFP91
Homology/Alignments : Family Browser (UCSC)ZFP91
Gene fusions - Rearrangements
Fusion : QuiverZFP91
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFP91 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFP91
dbVarZFP91
ClinVarZFP91
MonarchZFP91
1000_GenomesZFP91 
Exome Variant ServerZFP91
GNOMAD BrowserENSG00000186660
Varsome BrowserZFP91
ACMGZFP91 variants
VarityQ96JP5
Genomic Variants (DGV)ZFP91 [DGVbeta]
DECIPHERZFP91 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFP91 
Mutations
ICGC Data PortalZFP91 
TCGA Data PortalZFP91 
Broad Tumor PortalZFP91
OASIS PortalZFP91 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFP91  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZFP91
Mutations and Diseases : HGMDZFP91
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZFP91
DgiDB (Drug Gene Interaction Database)ZFP91
DoCM (Curated mutations)ZFP91
CIViC (Clinical Interpretations of Variants in Cancer)ZFP91
Cancer3DZFP91
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM619289   
Orphanet
DisGeNETZFP91
MedgenZFP91
Genetic Testing Registry ZFP91
NextProtQ96JP5 [Medical]
GENETestsZFP91
Target ValidationZFP91
Huge Navigator ZFP91 [HugePedia]
ClinGenZFP91
Clinical trials, drugs, therapy
MyCancerGenomeZFP91
Protein Interactions : CTDZFP91
Pharm GKB GenePA37955
PharosQ96JP5
Clinical trialZFP91
Miscellaneous
canSAR (ICR)ZFP91
HarmonizomeZFP91
DataMed IndexZFP91
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZFP91
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:38:58 CEST 2021

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