Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZFPM1 (zinc finger protein, FOG family member 1)

Identity

Alias_nameszinc finger protein
Alias_symbol (synonym)FOG1
FOG
ZNF89A
ZC2HC11A
Other aliasZNF408
HGNC (Hugo) ZFPM1
LocusID (NCBI) 161882
Atlas_Id 55763
Location 16q24.2  [Link to chromosome band 16q24]
Location_base_pair Starts at 88453606 and ends at 88535166 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KCNJ15 (21q22.13) / ZFPM1 (16q24.2)MAOA (Xp11.3) / ZFPM1 (16q24.2)ZFPM1 (16q24.2) / KLF6 (10p15.1)
ZFPM1 (16q24.2) / SLC7A5 (16q24.2)ZNF469 (16q24.2) / ZFPM1 (16q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZFPM1   19762
Cards
Entrez_Gene (NCBI)ZFPM1  161882  zinc finger protein, FOG family member 1
AliasesFOG; FOG1; ZC2HC11A; ZNF408; 
ZNF89A
GeneCards (Weizmann)ZFPM1
Ensembl hg19 (Hinxton)ENSG00000179588 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179588 [Gene_View]  chr16:88453606-88535166 [Contig_View]  ZFPM1 [Vega]
ICGC DataPortalENSG00000179588
TCGA cBioPortalZFPM1
AceView (NCBI)ZFPM1
Genatlas (Paris)ZFPM1
WikiGenes161882
SOURCE (Princeton)ZFPM1
Genetics Home Reference (NIH)ZFPM1
Genomic and cartography
GoldenPath hg38 (UCSC)ZFPM1  -     chr16:88453606-88535166 +  16q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFPM1  -     16q24.2   [Description]    (hg19-Feb_2009)
EnsemblZFPM1 - 16q24.2 [CytoView hg19]  ZFPM1 - 16q24.2 [CytoView hg38]
Mapping of homologs : NCBIZFPM1 [Mapview hg19]  ZFPM1 [Mapview hg38]
OMIM601950   
Gene and transcription
Genbank (Entrez)AF488691 BE219988
RefSeq transcript (Entrez)NM_153813
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFPM1
Cluster EST : UnigeneHs.632218 [ NCBI ]
CGAP (NCI)Hs.632218
Alternative Splicing GalleryENSG00000179588
Gene ExpressionZFPM1 [ NCBI-GEO ]   ZFPM1 [ EBI - ARRAY_EXPRESS ]   ZFPM1 [ SEEK ]   ZFPM1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFPM1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)161882
GTEX Portal (Tissue expression)ZFPM1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IX07   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IX07  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IX07
Splice isoforms : SwissVarQ8IX07
PhosPhoSitePlusQ8IX07
Domaine pattern : Prosite (Expaxy)ZF_CCHC_FOG (PS51810)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZFPM1
DMDM Disease mutations161882
Blocks (Seattle)ZFPM1
PDB (SRS)2XU7   
PDB (PDBSum)2XU7   
PDB (IMB)2XU7   
PDB (RSDB)2XU7   
Structural Biology KnowledgeBase2XU7   
SCOP (Structural Classification of Proteins)2XU7   
CATH (Classification of proteins structures)2XU7   
SuperfamilyQ8IX07
Human Protein AtlasENSG00000179588
Peptide AtlasQ8IX07
HPRD11800
IPIIPI00217346   
Protein Interaction databases
DIP (DOE-UCLA)Q8IX07
IntAct (EBI)Q8IX07
FunCoupENSG00000179588
BioGRIDZFPM1
STRING (EMBL)ZFPM1
ZODIACZFPM1
Ontologies - Pathways
QuickGOQ8IX07
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  RNA polymerase II transcription factor binding  RNA polymerase II activating transcription factor binding  T-helper cell lineage commitment  outflow tract morphogenesis  atrioventricular valve morphogenesis  mitral valve formation  tricuspid valve formation  protein binding  nucleus  nucleoplasm  transcription factor complex  cytoplasm  transcription, DNA-templated  heart development  blood coagulation  transcription factor binding  regulation of definitive erythrocyte differentiation  regulation of definitive erythrocyte differentiation  transcriptional repressor complex  erythrocyte differentiation  megakaryocyte differentiation  megakaryocyte differentiation  platelet formation  granulocyte differentiation  negative regulation of protein binding  regulation of chemokine production  embryonic hemopoiesis  megakaryocyte development  positive regulation of interferon-gamma biosynthetic process  negative regulation of interleukin-4 biosynthetic process  negative regulation of fat cell differentiation  metal ion binding  cardiac muscle tissue morphogenesis  definitive erythrocyte differentiation  primitive erythrocyte differentiation  negative regulation of mast cell differentiation  ventricular septum morphogenesis  atrial septum morphogenesis  transcriptional activation by promoter-enhancer looping  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  RNA polymerase II transcription factor binding  RNA polymerase II activating transcription factor binding  T-helper cell lineage commitment  outflow tract morphogenesis  atrioventricular valve morphogenesis  mitral valve formation  tricuspid valve formation  protein binding  nucleus  nucleoplasm  transcription factor complex  cytoplasm  transcription, DNA-templated  heart development  blood coagulation  transcription factor binding  regulation of definitive erythrocyte differentiation  regulation of definitive erythrocyte differentiation  transcriptional repressor complex  erythrocyte differentiation  megakaryocyte differentiation  megakaryocyte differentiation  platelet formation  granulocyte differentiation  negative regulation of protein binding  regulation of chemokine production  embryonic hemopoiesis  megakaryocyte development  positive regulation of interferon-gamma biosynthetic process  negative regulation of interleukin-4 biosynthetic process  negative regulation of fat cell differentiation  metal ion binding  cardiac muscle tissue morphogenesis  definitive erythrocyte differentiation  primitive erythrocyte differentiation  negative regulation of mast cell differentiation  ventricular septum morphogenesis  atrial septum morphogenesis  transcriptional activation by promoter-enhancer looping  
NDEx NetworkZFPM1
Atlas of Cancer Signalling NetworkZFPM1
Wikipedia pathwaysZFPM1
Orthology - Evolution
OrthoDB161882
GeneTree (enSembl)ENSG00000179588
Phylogenetic Trees/Animal Genes : TreeFamZFPM1
HOVERGENQ8IX07
HOGENOMQ8IX07
Homologs : HomoloGeneZFPM1
Homology/Alignments : Family Browser (UCSC)ZFPM1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFPM1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFPM1
dbVarZFPM1
ClinVarZFPM1
1000_GenomesZFPM1 
Exome Variant ServerZFPM1
ExAC (Exome Aggregation Consortium)ZFPM1 (select the gene name)
Genetic variants : HAPMAP161882
Genomic Variants (DGV)ZFPM1 [DGVbeta]
DECIPHERZFPM1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFPM1 
Mutations
ICGC Data PortalZFPM1 
TCGA Data PortalZFPM1 
Broad Tumor PortalZFPM1
OASIS PortalZFPM1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFPM1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFPM1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFPM1
DgiDB (Drug Gene Interaction Database)ZFPM1
DoCM (Curated mutations)ZFPM1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFPM1 (select a term)
intoGenZFPM1
Cancer3DZFPM1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601950   
Orphanet
MedgenZFPM1
Genetic Testing Registry ZFPM1
NextProtQ8IX07 [Medical]
TSGene161882
GENETestsZFPM1
Target ValidationZFPM1
Huge Navigator ZFPM1 [HugePedia]
snp3D : Map Gene to Disease161882
BioCentury BCIQZFPM1
ClinGenZFPM1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD161882
Chemical/Pharm GKB GenePA134920282
Clinical trialZFPM1
Miscellaneous
canSAR (ICR)ZFPM1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFPM1
EVEXZFPM1
GoPubMedZFPM1
iHOPZFPM1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:31 CEST 2017

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