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ZFPM2 (zinc finger protein, FOG family member 2)

Identity

Other namesDIH3
FOG2
ZC2HC11B
ZNF89B
hFOG-2
HGNC (Hugo) ZFPM2
LocusID (NCBI) 23414
Location 8q23.1
Location_base_pair Starts at 106331147 and ends at 106816767 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas)

Leukemias 11q23ChildAMLID1615

External links

Nomenclature
HGNC (Hugo)ZFPM2   16700
Cards
Entrez_Gene (NCBI)ZFPM2  23414  zinc finger protein, FOG family member 2
GeneCards (Weizmann)ZFPM2
Ensembl (Hinxton)ENSG00000169946 [Gene_View]  chr8:106331147-106816767 [Contig_View]  ZFPM2 [Vega]
ICGC DataPortalENSG00000169946
AceView (NCBI)ZFPM2
Genatlas (Paris)ZFPM2
WikiGenes23414
SOURCE (Princeton)NM_012082
Genomic and cartography
GoldenPath (UCSC)ZFPM2  -  8q23.1   chr8:106331147-106816767 +  8q23.1   [Description]    (hg19-Feb_2009)
EnsemblZFPM2 - 8q23.1 [CytoView]
Mapping of homologs : NCBIZFPM2 [Mapview]
OMIM187500   603693   610187   
Gene and transcription
Genbank (Entrez)AB073894 AF119334 AK296997 AK303058 AK316426
RefSeq transcript (Entrez)NM_012082
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_011723 NT_008046 NW_001839136 NW_004929340
Consensus coding sequences : CCDS (NCBI)ZFPM2
Cluster EST : UnigeneHs.431009 [ NCBI ]
CGAP (NCI)Hs.431009
Alternative Splicing : Fast-db (Paris)GSHG0029195
Alternative Splicing GalleryENSG00000169946
Gene ExpressionZFPM2 [ NCBI-GEO ]     ZFPM2 [ SEEK ]   ZFPM2 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WW38 (Uniprot)
NextProtQ8WW38  [Medical]
With graphics : InterProQ8WW38
Splice isoforms : SwissVarQ8WW38 (Swissvar)
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Related proteins : CluSTrQ8WW38
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
DMDM Disease mutations23414
Blocks (Seattle)Q8WW38
Human Protein AtlasENSG00000169946
Peptide AtlasQ8WW38
HPRD04737
IPIIPI00015802   IPI00410662   IPI01013613   IPI00978516   IPI00977707   
Protein Interaction databases
DIP (DOE-UCLA)Q8WW38
IntAct (EBI)Q8WW38
FunCoupENSG00000169946
BioGRIDZFPM2
IntegromeDBZFPM2
STRING (EMBL)ZFPM2
Ontologies - Pathways
QuickGOQ8WW38
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  nucleic acid binding transcription factor activity  RNA polymerase II transcription coactivator activity  vasculogenesis  in utero embryonic development  outflow tract septum morphogenesis  right ventricular cardiac muscle tissue morphogenesis  DNA binding  transcription corepressor activity  protein binding  nucleoplasm  cytoplasm  transcription, DNA-templated  blood coagulation  transcription factor binding  zinc ion binding  lung development  negative regulation of fat cell differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  embryonic organ development  ventricular septum morphogenesis  negative regulation of cell death  positive regulation of male gonad development  negative regulation of female gonad development  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  nucleic acid binding transcription factor activity  RNA polymerase II transcription coactivator activity  vasculogenesis  in utero embryonic development  outflow tract septum morphogenesis  right ventricular cardiac muscle tissue morphogenesis  DNA binding  transcription corepressor activity  protein binding  nucleoplasm  cytoplasm  transcription, DNA-templated  blood coagulation  transcription factor binding  zinc ion binding  lung development  negative regulation of fat cell differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  embryonic organ development  ventricular septum morphogenesis  negative regulation of cell death  positive regulation of male gonad development  negative regulation of female gonad development  
Pathways : KEGGMicroRNAs in cancer   
Protein Interaction DatabaseZFPM2
Wikipedia pathwaysZFPM2
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ZFPM2
SNP (GeneSNP Utah)ZFPM2
SNP : HGBaseZFPM2
Genetic variants : HAPMAPZFPM2
1000_GenomesZFPM2 
ICGC programENSG00000169946 
CONAN: Copy Number AnalysisZFPM2 
Somatic Mutations in Cancer : COSMICZFPM2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)8:106331147-106816767
Mutations and Diseases : HGMDZFPM2
OMIM187500    603693    610187   
MedgenZFPM2
GENETestsZFPM2
Disease Genetic AssociationZFPM2
Huge Navigator ZFPM2 [HugePedia]  ZFPM2 [HugeCancerGEM]
Genomic VariantsZFPM2  ZFPM2 [DGVbeta]
Exome VariantZFPM2
dbVarZFPM2
ClinVarZFPM2
snp3D : Map Gene to Disease23414
General knowledge
Homologs : HomoloGeneZFPM2
Homology/Alignments : Family Browser (UCSC)ZFPM2
Phylogenetic Trees/Animal Genes : TreeFamZFPM2
Chemical/Protein Interactions : CTD23414
Chemical/Pharm GKB GenePA134947303
Clinical trialZFPM2
Cancer Resource (Charite)ENSG00000169946
Other databases
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
CoreMineZFPM2
GoPubMedZFPM2
iHOPZFPM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 18:06:34 CET 2014

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