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ZFR (zinc finger RNA binding protein)

Identity

Alias_symbol (synonym)ZFR1
SPG71
Other alias
HGNC (Hugo) ZFR
LocusID (NCBI) 51663
Atlas_Id 54799
Location 5p13.3  [Link to chromosome band 5p13]
Location_base_pair Starts at 32354456 and ends at 32444844 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADAMTS12 (5p13.3) / ZFR (5p13.3)CD47 (3q13.12) / ZFR (5p13.3)DARS2 (1q25.1) / ZFR (5p13.3)
FKBP4 (12p13.33) / ZFR (5p13.3)MTMR12 (5p13.3) / ZFR (5p13.3)ZFR (5p13.3) / DARS2 (1q25.1)
ZFR (5p13.3) / PRKAR1B (7p22.3)ZFR (5p13.3) / SND1 (7q32.1)ZFR (5p13.3) / TARS (5p13.3)
ZFR (5p13.3) / ZFR (5p13.3)ZNF333 (19p13.12) / ZFR (5p13.3)ADAMTS12 5p13.3 / ZFR 5p13.3
CD47 3q13.12 / ZFR 5p13.3MTMR12 5p13.3 / ZFR 5p13.3ZFR 5p13.3 / SND1 7q32.1
ZFR 5p13.3 / TARS 5p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ZFR   17277
Cards
Entrez_Gene (NCBI)ZFR  51663  zinc finger RNA binding protein
AliasesSPG71; ZFR1
GeneCards (Weizmann)ZFR
Ensembl hg19 (Hinxton)ENSG00000056097 [Gene_View]  chr5:32354456-32444844 [Contig_View]  ZFR [Vega]
Ensembl hg38 (Hinxton)ENSG00000056097 [Gene_View]  chr5:32354456-32444844 [Contig_View]  ZFR [Vega]
ICGC DataPortalENSG00000056097
TCGA cBioPortalZFR
AceView (NCBI)ZFR
Genatlas (Paris)ZFR
WikiGenes51663
SOURCE (Princeton)ZFR
Genetics Home Reference (NIH)ZFR
Genomic and cartography
GoldenPath hg19 (UCSC)ZFR  -     chr5:32354456-32444844 -  5p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZFR  -     5p13.3   [Description]    (hg38-Dec_2013)
EnsemblZFR - 5p13.3 [CytoView hg19]  ZFR - 5p13.3 [CytoView hg38]
Mapping of homologs : NCBIZFR [Mapview hg19]  ZFR [Mapview hg38]
OMIM615635   
Gene and transcription
Genbank (Entrez)AF100742 AJ314790 AK025481 AK055938 AK123306
RefSeq transcript (Entrez)NM_016107
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_006576 NW_004929321
Consensus coding sequences : CCDS (NCBI)ZFR
Cluster EST : UnigeneHs.435231 [ NCBI ]
CGAP (NCI)Hs.435231
Alternative Splicing GalleryENSG00000056097
Gene ExpressionZFR [ NCBI-GEO ]   ZFR [ EBI - ARRAY_EXPRESS ]   ZFR [ SEEK ]   ZFR [ MEM ]
Gene Expression Viewer (FireBrowse)ZFR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51663
GTEX Portal (Tissue expression)ZFR
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KR1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96KR1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96KR1
Splice isoforms : SwissVarQ96KR1
PhosPhoSitePlusQ96KR1
Domaine pattern : Prosite (Expaxy)DZF (PS51703)    ZINC_FINGER_C2H2_1 (PS00028)   
Domains : Interpro (EBI)DZF_dom    Znf_C2H2    Znf_C2H2-like    Znf_U1   
Domain families : Pfam (Sanger)DZF (PF07528)   
Domain families : Pfam (NCBI)pfam07528   
Domain families : Smart (EMBL)DZF (SM00572)  ZnF_C2H2 (SM00355)  ZnF_U1 (SM00451)  
Conserved Domain (NCBI)ZFR
DMDM Disease mutations51663
Blocks (Seattle)ZFR
SuperfamilyQ96KR1
Human Protein AtlasENSG00000056097
Peptide AtlasQ96KR1
HPRD15730
IPIIPI00748303   IPI00807564   IPI00784224   
Protein Interaction databases
DIP (DOE-UCLA)Q96KR1
IntAct (EBI)Q96KR1
FunCoupENSG00000056097
BioGRIDZFR
STRING (EMBL)ZFR
ZODIACZFR
Ontologies - Pathways
QuickGOQ96KR1
Ontology : AmiGODNA binding  protein binding  nucleoplasm  chromosome  cytoplasm  multicellular organism development  zinc ion binding  poly(A) RNA binding  
Ontology : EGO-EBIDNA binding  protein binding  nucleoplasm  chromosome  cytoplasm  multicellular organism development  zinc ion binding  poly(A) RNA binding  
NDEx NetworkZFR
Atlas of Cancer Signalling NetworkZFR
Wikipedia pathwaysZFR
Orthology - Evolution
OrthoDB51663
GeneTree (enSembl)ENSG00000056097
Phylogenetic Trees/Animal Genes : TreeFamZFR
HOVERGENQ96KR1
HOGENOMQ96KR1
Homologs : HomoloGeneZFR
Homology/Alignments : Family Browser (UCSC)ZFR
Gene fusions - Rearrangements
Fusion : MitelmanADAMTS12/ZFR [5p13.3/5p13.3]  [t(5;5)(p13;p13)]  
Fusion : MitelmanCD47/ZFR [3q13.12/5p13.3]  [t(3;5)(q13;p13)]  
Fusion : MitelmanDARS2/ZFR [1q25.1/5p13.3]  [t(1;5)(q25;p13)]  
Fusion : MitelmanMTMR12/ZFR [5p13.3/5p13.3]  [t(5;5)(p13;p13)]  
Fusion : MitelmanZFR/DARS2 [5p13.3/1q25.1]  [t(1;5)(q25;p13)]  
Fusion : MitelmanZFR/SND1 [5p13.3/7q32.1]  [t(5;7)(p13;q32)]  
Fusion : MitelmanZFR/TARS [5p13.3/5p13.3]  [t(5;5)(p13;p13)]  
Fusion: TCGAADAMTS12 5p13.3 ZFR 5p13.3 BRCA
Fusion: TCGACD47 3q13.12 ZFR 5p13.3 PRAD
Fusion: TCGAMTMR12 5p13.3 ZFR 5p13.3 LUAD
Fusion: TCGAZFR 5p13.3 SND1 7q32.1 OV
Fusion: TCGAZFR 5p13.3 TARS 5p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFR
dbVarZFR
ClinVarZFR
1000_GenomesZFR 
Exome Variant ServerZFR
ExAC (Exome Aggregation Consortium)ZFR (select the gene name)
Genetic variants : HAPMAP51663
Genomic Variants (DGV)ZFR [DGVbeta]
DECIPHER (Syndromes)5:32354456-32444844  ENSG00000056097
CONAN: Copy Number AnalysisZFR 
Mutations
ICGC Data PortalZFR 
TCGA Data PortalZFR 
Broad Tumor PortalZFR
OASIS PortalZFR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFR
DgiDB (Drug Gene Interaction Database)ZFR
DoCM (Curated mutations)ZFR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFR (select a term)
intoGenZFR
Cancer3DZFR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615635   
Orphanet22839   
MedgenZFR
Genetic Testing Registry ZFR
NextProtQ96KR1 [Medical]
TSGene51663
GENETestsZFR
Huge Navigator ZFR [HugePedia]
snp3D : Map Gene to Disease51663
BioCentury BCIQZFR
ClinGenZFR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51663
Chemical/Pharm GKB GenePA38219
Clinical trialZFR
Miscellaneous
canSAR (ICR)ZFR (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFR
EVEXZFR
GoPubMedZFR
iHOPZFR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:25:33 CEST 2017

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