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ZFYVE16 (zinc finger FYVE-type containing 16)

Identity

Alias_nameszinc finger, FYVE domain containing 16
Alias_symbol (synonym)KIAA0305
PPP1R69
Other alias
HGNC (Hugo) ZFYVE16
LocusID (NCBI) 9765
Atlas_Id 75952
Location 5q14.1  [Link to chromosome band 5q14]
Location_base_pair Starts at 80408013 and ends at 80483379 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SERINC5 (5q14.1) / ZFYVE16 (5q14.1)ZFYVE16 (5q14.1) / ZFP90 (16q22.1)ZFYVE16 (5q14.1) / ZFYVE16 (5q14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZFYVE16   20756
Cards
Entrez_Gene (NCBI)ZFYVE16  9765  zinc finger FYVE-type containing 16
AliasesPPP1R69
GeneCards (Weizmann)ZFYVE16
Ensembl hg19 (Hinxton)ENSG00000039319 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000039319 [Gene_View]  chr5:80408013-80483379 [Contig_View]  ZFYVE16 [Vega]
ICGC DataPortalENSG00000039319
TCGA cBioPortalZFYVE16
AceView (NCBI)ZFYVE16
Genatlas (Paris)ZFYVE16
WikiGenes9765
SOURCE (Princeton)ZFYVE16
Genetics Home Reference (NIH)ZFYVE16
Genomic and cartography
GoldenPath hg38 (UCSC)ZFYVE16  -     chr5:80408013-80483379 +  5q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFYVE16  -     5q14.1   [Description]    (hg19-Feb_2009)
EnsemblZFYVE16 - 5q14.1 [CytoView hg19]  ZFYVE16 - 5q14.1 [CytoView hg38]
Mapping of homologs : NCBIZFYVE16 [Mapview hg19]  ZFYVE16 [Mapview hg38]
OMIM608880   
Gene and transcription
Genbank (Entrez)AB002303 AF434817 AK090896 AK127003 AL833087
RefSeq transcript (Entrez)NM_001105251 NM_001284236 NM_001284237 NM_001349434 NM_014733
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFYVE16
Cluster EST : UnigeneHs.660410 [ NCBI ]
CGAP (NCI)Hs.660410
Alternative Splicing GalleryENSG00000039319
Gene ExpressionZFYVE16 [ NCBI-GEO ]   ZFYVE16 [ EBI - ARRAY_EXPRESS ]   ZFYVE16 [ SEEK ]   ZFYVE16 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFYVE16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9765
GTEX Portal (Tissue expression)ZFYVE16
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z3T8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z3T8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z3T8
Splice isoforms : SwissVarQ7Z3T8
PhosPhoSitePlusQ7Z3T8
Domaine pattern : Prosite (Expaxy)ZF_FYVE (PS50178)   
Domains : Interpro (EBI)DUF3480    Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_endofin    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)DUF3480 (PF11979)    FYVE (PF01363)   
Domain families : Pfam (NCBI)pfam11979    pfam01363   
Domain families : Smart (EMBL)FYVE (SM00064)  
Conserved Domain (NCBI)ZFYVE16
DMDM Disease mutations9765
Blocks (Seattle)ZFYVE16
PDB (SRS)3T7L   
PDB (PDBSum)3T7L   
PDB (IMB)3T7L   
PDB (RSDB)3T7L   
Structural Biology KnowledgeBase3T7L   
SCOP (Structural Classification of Proteins)3T7L   
CATH (Classification of proteins structures)3T7L   
SuperfamilyQ7Z3T8
Human Protein AtlasENSG00000039319
Peptide AtlasQ7Z3T8
HPRD10319
IPIIPI00424460   IPI00424466   IPI00964599   IPI00968247   IPI00967444   IPI00964837   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z3T8
IntAct (EBI)Q7Z3T8
FunCoupENSG00000039319
BioGRIDZFYVE16
STRING (EMBL)ZFYVE16
ZODIACZFYVE16
Ontologies - Pathways
QuickGOQ7Z3T8
Ontology : AmiGOprotein binding  1-phosphatidylinositol binding  phosphatidylinositol-3,4,5-trisphosphate binding  early endosome  cytosol  protein targeting to lysosome  signal transduction  protein transporter activity  vesicle organization  endosomal transport  regulation of endocytosis  BMP signaling pathway  early endosome membrane  intracellular membrane-bounded organelle  metal ion binding  
Ontology : EGO-EBIprotein binding  1-phosphatidylinositol binding  phosphatidylinositol-3,4,5-trisphosphate binding  early endosome  cytosol  protein targeting to lysosome  signal transduction  protein transporter activity  vesicle organization  endosomal transport  regulation of endocytosis  BMP signaling pathway  early endosome membrane  intracellular membrane-bounded organelle  metal ion binding  
Pathways : KEGGEndocytosis    TGF-beta signaling pathway   
NDEx NetworkZFYVE16
Atlas of Cancer Signalling NetworkZFYVE16
Wikipedia pathwaysZFYVE16
Orthology - Evolution
OrthoDB9765
GeneTree (enSembl)ENSG00000039319
Phylogenetic Trees/Animal Genes : TreeFamZFYVE16
HOVERGENQ7Z3T8
HOGENOMQ7Z3T8
Homologs : HomoloGeneZFYVE16
Homology/Alignments : Family Browser (UCSC)ZFYVE16
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFYVE16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFYVE16
dbVarZFYVE16
ClinVarZFYVE16
1000_GenomesZFYVE16 
Exome Variant ServerZFYVE16
ExAC (Exome Aggregation Consortium)ZFYVE16 (select the gene name)
Genetic variants : HAPMAP9765
Genomic Variants (DGV)ZFYVE16 [DGVbeta]
DECIPHERZFYVE16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFYVE16 
Mutations
ICGC Data PortalZFYVE16 
TCGA Data PortalZFYVE16 
Broad Tumor PortalZFYVE16
OASIS PortalZFYVE16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFYVE16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFYVE16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFYVE16
DgiDB (Drug Gene Interaction Database)ZFYVE16
DoCM (Curated mutations)ZFYVE16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFYVE16 (select a term)
intoGenZFYVE16
Cancer3DZFYVE16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608880   
Orphanet
MedgenZFYVE16
Genetic Testing Registry ZFYVE16
NextProtQ7Z3T8 [Medical]
TSGene9765
GENETestsZFYVE16
Target ValidationZFYVE16
Huge Navigator ZFYVE16 [HugePedia]
snp3D : Map Gene to Disease9765
BioCentury BCIQZFYVE16
ClinGenZFYVE16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9765
Chemical/Pharm GKB GenePA134873366
Clinical trialZFYVE16
Miscellaneous
canSAR (ICR)ZFYVE16 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFYVE16
EVEXZFYVE16
GoPubMedZFYVE16
iHOPZFYVE16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:49:46 CEST 2017

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