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ZFYVE19 (zinc finger FYVE-type containing 19)

Identity

Alias_nameszinc finger
Alias_symbol (synonym)FLJ14840
ANCHR
Other aliasMPFYVE
HGNC (Hugo) ZFYVE19
LocusID (NCBI) 84936
Atlas_Id 54800
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 40807076 and ends at 40814569 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KMT2A (11q23.3) / ZFYVE19 (15q15.1)VPS18 (15q15.1) / ZFYVE19 (15q15.1)ZFYVE19 (15q15.1) / ZFYVE19 (15q15.1)
KMT2A 11q23.3 / ZFYVE19 15q15.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Protein

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;15)(q23;q14) KMT2A/ZFYVE19


External links

Nomenclature
HGNC (Hugo)ZFYVE19   20758
Cards
Entrez_Gene (NCBI)ZFYVE19  84936  zinc finger FYVE-type containing 19
AliasesANCHR; MPFYVE
GeneCards (Weizmann)ZFYVE19
Ensembl hg19 (Hinxton)ENSG00000166140 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166140 [Gene_View]  chr15:40807076-40814569 [Contig_View]  ZFYVE19 [Vega]
ICGC DataPortalENSG00000166140
TCGA cBioPortalZFYVE19
AceView (NCBI)ZFYVE19
Genatlas (Paris)ZFYVE19
WikiGenes84936
SOURCE (Princeton)ZFYVE19
Genetics Home Reference (NIH)ZFYVE19
Genomic and cartography
GoldenPath hg38 (UCSC)ZFYVE19  -     chr15:40807076-40814569 +  15q15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZFYVE19  -     15q15.1   [Description]    (hg19-Feb_2009)
EnsemblZFYVE19 - 15q15.1 [CytoView hg19]  ZFYVE19 - 15q15.1 [CytoView hg38]
Mapping of homologs : NCBIZFYVE19 [Mapview hg19]  ZFYVE19 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB209224 AF445414 AK027746 AK122779 AK225553
RefSeq transcript (Entrez)NM_001077268 NM_001258420 NM_001258421 NM_032850
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZFYVE19
Cluster EST : UnigeneHs.121676 [ NCBI ]
CGAP (NCI)Hs.121676
Alternative Splicing GalleryENSG00000166140
Gene ExpressionZFYVE19 [ NCBI-GEO ]   ZFYVE19 [ EBI - ARRAY_EXPRESS ]   ZFYVE19 [ SEEK ]   ZFYVE19 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFYVE19 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84936
GTEX Portal (Tissue expression)ZFYVE19
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96K21   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96K21  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96K21
Splice isoforms : SwissVarQ96K21
PhosPhoSitePlusQ96K21
Domaine pattern : Prosite (Expaxy)ZF_FYVE (PS50178)   
Domains : Interpro (EBI)Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)FYVE (PF01363)   
Domain families : Pfam (NCBI)pfam01363   
Domain families : Smart (EMBL)FYVE (SM00064)  
Conserved Domain (NCBI)ZFYVE19
DMDM Disease mutations84936
Blocks (Seattle)ZFYVE19
SuperfamilyQ96K21
Human Protein AtlasENSG00000166140
Peptide AtlasQ96K21
HPRD15731
IPIIPI00386862   IPI00329053   IPI00102875   IPI00555885   
Protein Interaction databases
DIP (DOE-UCLA)Q96K21
IntAct (EBI)Q96K21
FunCoupENSG00000166140
BioGRIDZFYVE19
STRING (EMBL)ZFYVE19
ZODIACZFYVE19
Ontologies - Pathways
QuickGOQ96K21
Ontology : AmiGOprotein binding  cytoplasm  centrosome  cell cycle  abscission  midbody  cleavage furrow  phosphatidylinositol-3-phosphate binding  negative regulation of cytokinesis  metal ion binding  cell division  
Ontology : EGO-EBIprotein binding  cytoplasm  centrosome  cell cycle  abscission  midbody  cleavage furrow  phosphatidylinositol-3-phosphate binding  negative regulation of cytokinesis  metal ion binding  cell division  
NDEx NetworkZFYVE19
Atlas of Cancer Signalling NetworkZFYVE19
Wikipedia pathwaysZFYVE19
Orthology - Evolution
OrthoDB84936
GeneTree (enSembl)ENSG00000166140
Phylogenetic Trees/Animal Genes : TreeFamZFYVE19
HOVERGENQ96K21
HOGENOMQ96K21
Homologs : HomoloGeneZFYVE19
Homology/Alignments : Family Browser (UCSC)ZFYVE19
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFYVE19 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFYVE19
dbVarZFYVE19
ClinVarZFYVE19
1000_GenomesZFYVE19 
Exome Variant ServerZFYVE19
ExAC (Exome Aggregation Consortium)ZFYVE19 (select the gene name)
Genetic variants : HAPMAP84936
Genomic Variants (DGV)ZFYVE19 [DGVbeta]
DECIPHERZFYVE19 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZFYVE19 
Mutations
ICGC Data PortalZFYVE19 
TCGA Data PortalZFYVE19 
Broad Tumor PortalZFYVE19
OASIS PortalZFYVE19 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFYVE19  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFYVE19
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFYVE19
DgiDB (Drug Gene Interaction Database)ZFYVE19
DoCM (Curated mutations)ZFYVE19 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFYVE19 (select a term)
intoGenZFYVE19
Cancer3DZFYVE19(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZFYVE19
Genetic Testing Registry ZFYVE19
NextProtQ96K21 [Medical]
TSGene84936
GENETestsZFYVE19
Huge Navigator ZFYVE19 [HugePedia]
snp3D : Map Gene to Disease84936
BioCentury BCIQZFYVE19
ClinGenZFYVE19
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84936
Chemical/Pharm GKB GenePA134906967
Clinical trialZFYVE19
Miscellaneous
canSAR (ICR)ZFYVE19 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFYVE19
EVEXZFYVE19
GoPubMedZFYVE19
iHOPZFYVE19
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:44:45 CEST 2017

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