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ZFYVE28 (zinc finger, FYVE domain containing 28)

Identity

Alias_nameszinc finger, FYVE domain containing 28
Alias_symbol (synonym)KIAA1643
Other aliasLST2
LYST2
HGNC (Hugo) ZFYVE28
LocusID (NCBI) 57732
Atlas_Id 75955
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 2271324 and ends at 2420370 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZFYVE28   29334
Cards
Entrez_Gene (NCBI)ZFYVE28  57732  zinc finger, FYVE domain containing 28
AliasesLST2; LYST2
GeneCards (Weizmann)ZFYVE28
Ensembl hg19 (Hinxton)ENSG00000159733 [Gene_View]  chr4:2271324-2420370 [Contig_View]  ZFYVE28 [Vega]
Ensembl hg38 (Hinxton)ENSG00000159733 [Gene_View]  chr4:2271324-2420370 [Contig_View]  ZFYVE28 [Vega]
ICGC DataPortalENSG00000159733
TCGA cBioPortalZFYVE28
AceView (NCBI)ZFYVE28
Genatlas (Paris)ZFYVE28
WikiGenes57732
SOURCE (Princeton)ZFYVE28
Genetics Home Reference (NIH)ZFYVE28
Genomic and cartography
GoldenPath hg19 (UCSC)ZFYVE28  -     chr4:2271324-2420370 -  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZFYVE28  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblZFYVE28 - 4p16.3 [CytoView hg19]  ZFYVE28 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIZFYVE28 [Mapview hg19]  ZFYVE28 [Mapview hg38]
OMIM614176   
Gene and transcription
Genbank (Entrez)AB046863 AK126692 AK293775 AK294710 AK294874
RefSeq transcript (Entrez)NM_001172656 NM_001172657 NM_001172658 NM_001172659 NM_001172660 NM_020972
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006051 NW_004929314
Consensus coding sequences : CCDS (NCBI)ZFYVE28
Cluster EST : UnigeneHs.292056 [ NCBI ]
CGAP (NCI)Hs.292056
Alternative Splicing GalleryENSG00000159733
Gene ExpressionZFYVE28 [ NCBI-GEO ]   ZFYVE28 [ EBI - ARRAY_EXPRESS ]   ZFYVE28 [ SEEK ]   ZFYVE28 [ MEM ]
Gene Expression Viewer (FireBrowse)ZFYVE28 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57732
GTEX Portal (Tissue expression)ZFYVE28
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCC9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCC9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCC9
Splice isoforms : SwissVarQ9HCC9
PhosPhoSitePlusQ9HCC9
Domaine pattern : Prosite (Expaxy)ZF_FYVE (PS50178)   
Domains : Interpro (EBI)Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)FYVE (PF01363)   
Domain families : Pfam (NCBI)pfam01363   
Domain families : Smart (EMBL)FYVE (SM00064)  
Conserved Domain (NCBI)ZFYVE28
DMDM Disease mutations57732
Blocks (Seattle)ZFYVE28
SuperfamilyQ9HCC9
Human Protein AtlasENSG00000159733
Peptide AtlasQ9HCC9
HPRD11701
IPIIPI00288918   IPI00935557   IPI00936215   IPI00937916   IPI00937746   IPI00968014   IPI00968206   IPI00955996   IPI00956065   IPI00964586   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCC9
IntAct (EBI)Q9HCC9
FunCoupENSG00000159733
BioGRIDZFYVE28
STRING (EMBL)ZFYVE28
ZODIACZFYVE28
Ontologies - Pathways
QuickGOQ9HCC9
Ontology : AmiGOprotein binding  cytosol  negative regulation of epidermal growth factor-activated receptor activity  early endosome membrane  phosphatidylinositol-3-phosphate binding  negative regulation of epidermal growth factor receptor signaling pathway  metal ion binding  
Ontology : EGO-EBIprotein binding  cytosol  negative regulation of epidermal growth factor-activated receptor activity  early endosome membrane  phosphatidylinositol-3-phosphate binding  negative regulation of epidermal growth factor receptor signaling pathway  metal ion binding  
NDEx NetworkZFYVE28
Atlas of Cancer Signalling NetworkZFYVE28
Wikipedia pathwaysZFYVE28
Orthology - Evolution
OrthoDB57732
GeneTree (enSembl)ENSG00000159733
Phylogenetic Trees/Animal Genes : TreeFamZFYVE28
HOVERGENQ9HCC9
HOGENOMQ9HCC9
Homologs : HomoloGeneZFYVE28
Homology/Alignments : Family Browser (UCSC)ZFYVE28
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZFYVE28 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZFYVE28
dbVarZFYVE28
ClinVarZFYVE28
1000_GenomesZFYVE28 
Exome Variant ServerZFYVE28
ExAC (Exome Aggregation Consortium)ZFYVE28 (select the gene name)
Genetic variants : HAPMAP57732
Genomic Variants (DGV)ZFYVE28 [DGVbeta]
DECIPHER (Syndromes)4:2271324-2420370  ENSG00000159733
CONAN: Copy Number AnalysisZFYVE28 
Mutations
ICGC Data PortalZFYVE28 
TCGA Data PortalZFYVE28 
Broad Tumor PortalZFYVE28
OASIS PortalZFYVE28 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZFYVE28  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZFYVE28
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZFYVE28
DgiDB (Drug Gene Interaction Database)ZFYVE28
DoCM (Curated mutations)ZFYVE28 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZFYVE28 (select a term)
intoGenZFYVE28
Cancer3DZFYVE28(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614176   
Orphanet
MedgenZFYVE28
Genetic Testing Registry ZFYVE28
NextProtQ9HCC9 [Medical]
TSGene57732
GENETestsZFYVE28
Huge Navigator ZFYVE28 [HugePedia]
snp3D : Map Gene to Disease57732
BioCentury BCIQZFYVE28
ClinGenZFYVE28
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57732
Chemical/Pharm GKB GenePA134904138
Clinical trialZFYVE28
Miscellaneous
canSAR (ICR)ZFYVE28 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZFYVE28
EVEXZFYVE28
GoPubMedZFYVE28
iHOPZFYVE28
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:52:23 CET 2017

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