Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ZHX1 (zinc fingers and homeoboxes 1)

Identity

Alias_nameszinc-fingers and homeoboxes 1
Other alias-
HGNC (Hugo) ZHX1
LocusID (NCBI) 11244
Atlas_Id 55014
Location 8q24.13  [Link to chromosome band 8q24]
Location_base_pair Starts at 124260690 and ends at 124286727 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ZHX1 (8q24.13) / KMT2A (11q23.3)ZHX1 (8q24.13) / RALYL (8q21.2)ZHX1 8q24.13 / RALYL 8q21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZHX1   12871
Cards
Entrez_Gene (NCBI)ZHX1  11244  zinc fingers and homeoboxes 1
Aliases
GeneCards (Weizmann)ZHX1
Ensembl hg19 (Hinxton)ENSG00000165156 [Gene_View]  chr8:124260690-124286727 [Contig_View]  ZHX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000165156 [Gene_View]  chr8:124260690-124286727 [Contig_View]  ZHX1 [Vega]
ICGC DataPortalENSG00000165156
TCGA cBioPortalZHX1
AceView (NCBI)ZHX1
Genatlas (Paris)ZHX1
WikiGenes11244
SOURCE (Princeton)ZHX1
Genetics Home Reference (NIH)ZHX1
Genomic and cartography
GoldenPath hg19 (UCSC)ZHX1  -     chr8:124260690-124286727 -  8q24.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZHX1  -     8q24.13   [Description]    (hg38-Dec_2013)
EnsemblZHX1 - 8q24.13 [CytoView hg19]  ZHX1 - 8q24.13 [CytoView hg38]
Mapping of homologs : NCBIZHX1 [Mapview hg19]  ZHX1 [Mapview hg38]
OMIM604764   
Gene and transcription
Genbank (Entrez)AF106862 AF195766 AK025236 AK094451 AK289532
RefSeq transcript (Entrez)NM_001017926 NM_007222
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)ZHX1
Cluster EST : UnigeneHs.521800 [ NCBI ]
CGAP (NCI)Hs.521800
Alternative Splicing GalleryENSG00000165156
Gene ExpressionZHX1 [ NCBI-GEO ]   ZHX1 [ EBI - ARRAY_EXPRESS ]   ZHX1 [ SEEK ]   ZHX1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZHX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11244
GTEX Portal (Tissue expression)ZHX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UKY1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UKY1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UKY1
Splice isoforms : SwissVarQ9UKY1
PhosPhoSitePlusQ9UKY1
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Homeobox_dom    Homeodomain-like    Homez_dom    Znf_C2H2    Znf_C2H2-like   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Homez (PF11569)   
Domain families : Pfam (NCBI)pfam00046    pfam11569   
Domain families : Smart (EMBL)HOX (SM00389)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZHX1
DMDM Disease mutations11244
Blocks (Seattle)ZHX1
PDB (SRS)2ECB    2GHF    2LY9    3NAR   
PDB (PDBSum)2ECB    2GHF    2LY9    3NAR   
PDB (IMB)2ECB    2GHF    2LY9    3NAR   
PDB (RSDB)2ECB    2GHF    2LY9    3NAR   
Structural Biology KnowledgeBase2ECB    2GHF    2LY9    3NAR   
SCOP (Structural Classification of Proteins)2ECB    2GHF    2LY9    3NAR   
CATH (Classification of proteins structures)2ECB    2GHF    2LY9    3NAR   
SuperfamilyQ9UKY1
Human Protein AtlasENSG00000165156
Peptide AtlasQ9UKY1
HPRD10379
IPIIPI00293086   IPI00978077   IPI00974313   
Protein Interaction databases
DIP (DOE-UCLA)Q9UKY1
IntAct (EBI)Q9UKY1
FunCoupENSG00000165156
BioGRIDZHX1
STRING (EMBL)ZHX1
ZODIACZHX1
Ontologies - Pathways
QuickGOQ9UKY1
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  cell differentiation  negative regulation of transcription, DNA-templated  metal ion binding  protein heterodimerization activity  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  cell differentiation  negative regulation of transcription, DNA-templated  metal ion binding  protein heterodimerization activity  
NDEx NetworkZHX1
Atlas of Cancer Signalling NetworkZHX1
Wikipedia pathwaysZHX1
Orthology - Evolution
OrthoDB11244
GeneTree (enSembl)ENSG00000165156
Phylogenetic Trees/Animal Genes : TreeFamZHX1
HOVERGENQ9UKY1
HOGENOMQ9UKY1
Homologs : HomoloGeneZHX1
Homology/Alignments : Family Browser (UCSC)ZHX1
Gene fusions - Rearrangements
Fusion : MitelmanZHX1/RALYL [8q24.13/8q21.2]  
Fusion: TCGAZHX1 8q24.13 RALYL 8q21.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZHX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZHX1
dbVarZHX1
ClinVarZHX1
1000_GenomesZHX1 
Exome Variant ServerZHX1
ExAC (Exome Aggregation Consortium)ZHX1 (select the gene name)
Genetic variants : HAPMAP11244
Genomic Variants (DGV)ZHX1 [DGVbeta]
DECIPHER (Syndromes)8:124260690-124286727  ENSG00000165156
CONAN: Copy Number AnalysisZHX1 
Mutations
ICGC Data PortalZHX1 
TCGA Data PortalZHX1 
Broad Tumor PortalZHX1
OASIS PortalZHX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZHX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZHX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZHX1
DgiDB (Drug Gene Interaction Database)ZHX1
DoCM (Curated mutations)ZHX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZHX1 (select a term)
intoGenZHX1
Cancer3DZHX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604764   
Orphanet
MedgenZHX1
Genetic Testing Registry ZHX1
NextProtQ9UKY1 [Medical]
TSGene11244
GENETestsZHX1
Huge Navigator ZHX1 [HugePedia]
snp3D : Map Gene to Disease11244
BioCentury BCIQZHX1
ClinGenZHX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11244
Chemical/Pharm GKB GenePA37460
Clinical trialZHX1
Miscellaneous
canSAR (ICR)ZHX1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZHX1
EVEXZHX1
GoPubMedZHX1
iHOPZHX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:34:52 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.