Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ZHX3 (zinc fingers and homeoboxes 3)

Identity

Alias_namesTIX1
triple homeobox 1
Alias_symbol (synonym)KIAA0395
Other alias
HGNC (Hugo) ZHX3
LocusID (NCBI) 23051
Atlas_Id 75959
Location 20q12  [Link to chromosome band 20q12]
Location_base_pair Starts at 39807089 and ends at 39928739 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ZHX3 (20q12) / SPTBN1 (2p16.2)ZHX3 (20q12) / SRM (1p36.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZHX3   15935
Cards
Entrez_Gene (NCBI)ZHX3  23051  zinc fingers and homeoboxes 3
AliasesTIX1
GeneCards (Weizmann)ZHX3
Ensembl hg19 (Hinxton)ENSG00000174306 [Gene_View]  chr20:39807089-39928739 [Contig_View]  ZHX3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000174306 [Gene_View]  chr20:39807089-39928739 [Contig_View]  ZHX3 [Vega]
ICGC DataPortalENSG00000174306
TCGA cBioPortalZHX3
AceView (NCBI)ZHX3
Genatlas (Paris)ZHX3
WikiGenes23051
SOURCE (Princeton)ZHX3
Genetics Home Reference (NIH)ZHX3
Genomic and cartography
GoldenPath hg19 (UCSC)ZHX3  -     chr20:39807089-39928739 -  20q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZHX3  -     20q12   [Description]    (hg38-Dec_2013)
EnsemblZHX3 - 20q12 [CytoView hg19]  ZHX3 - 20q12 [CytoView hg38]
Mapping of homologs : NCBIZHX3 [Mapview hg19]  ZHX3 [Mapview hg38]
OMIM609598   
Gene and transcription
Genbank (Entrez)AB007855 AB081948 AI754653 AK090560 AK097523
RefSeq transcript (Entrez)NM_015035
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)ZHX3
Cluster EST : UnigeneHs.380133 [ NCBI ]
CGAP (NCI)Hs.380133
Alternative Splicing GalleryENSG00000174306
Gene ExpressionZHX3 [ NCBI-GEO ]   ZHX3 [ EBI - ARRAY_EXPRESS ]   ZHX3 [ SEEK ]   ZHX3 [ MEM ]
Gene Expression Viewer (FireBrowse)ZHX3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23051
GTEX Portal (Tissue expression)ZHX3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4I2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4I2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4I2
Splice isoforms : SwissVarQ9H4I2
PhosPhoSitePlusQ9H4I2
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_dom    Homeodomain-like    Homez_dom    Znf_C2H2-like   
Domain families : Pfam (Sanger)Homeobox (PF00046)    Homez (PF11569)   
Domain families : Pfam (NCBI)pfam00046    pfam11569   
Domain families : Smart (EMBL)HOX (SM00389)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZHX3
DMDM Disease mutations23051
Blocks (Seattle)ZHX3
PDB (SRS)2DA5    2DN0   
PDB (PDBSum)2DA5    2DN0   
PDB (IMB)2DA5    2DN0   
PDB (RSDB)2DA5    2DN0   
Structural Biology KnowledgeBase2DA5    2DN0   
SCOP (Structural Classification of Proteins)2DA5    2DN0   
CATH (Classification of proteins structures)2DA5    2DN0   
SuperfamilyQ9H4I2
Human Protein AtlasENSG00000174306
Peptide AtlasQ9H4I2
HPRD10320
IPIIPI00301844   IPI00645281   IPI00432409   IPI00645573   IPI00642081   IPI00642569   IPI00644670   IPI00645772   IPI00646853   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4I2
IntAct (EBI)Q9H4I2
FunCoupENSG00000174306
BioGRIDZHX3
STRING (EMBL)ZHX3
ZODIACZHX3
Ontologies - Pathways
QuickGOQ9H4I2
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  sequence-specific DNA binding transcription factor activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  cell differentiation  protein homodimerization activity  positive regulation of osteoblast differentiation  negative regulation of transcription, DNA-templated  metal ion binding  protein heterodimerization activity  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  sequence-specific DNA binding transcription factor activity  transcription corepressor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  cell differentiation  protein homodimerization activity  positive regulation of osteoblast differentiation  negative regulation of transcription, DNA-templated  metal ion binding  protein heterodimerization activity  
NDEx NetworkZHX3
Atlas of Cancer Signalling NetworkZHX3
Wikipedia pathwaysZHX3
Orthology - Evolution
OrthoDB23051
GeneTree (enSembl)ENSG00000174306
Phylogenetic Trees/Animal Genes : TreeFamZHX3
HOVERGENQ9H4I2
HOGENOMQ9H4I2
Homologs : HomoloGeneZHX3
Homology/Alignments : Family Browser (UCSC)ZHX3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZHX3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZHX3
dbVarZHX3
ClinVarZHX3
1000_GenomesZHX3 
Exome Variant ServerZHX3
ExAC (Exome Aggregation Consortium)ZHX3 (select the gene name)
Genetic variants : HAPMAP23051
Genomic Variants (DGV)ZHX3 [DGVbeta]
DECIPHER (Syndromes)20:39807089-39928739  ENSG00000174306
CONAN: Copy Number AnalysisZHX3 
Mutations
ICGC Data PortalZHX3 
TCGA Data PortalZHX3 
Broad Tumor PortalZHX3
OASIS PortalZHX3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZHX3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZHX3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZHX3
DgiDB (Drug Gene Interaction Database)ZHX3
DoCM (Curated mutations)ZHX3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZHX3 (select a term)
intoGenZHX3
Cancer3DZHX3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609598   
Orphanet
MedgenZHX3
Genetic Testing Registry ZHX3
NextProtQ9H4I2 [Medical]
TSGene23051
GENETestsZHX3
Huge Navigator ZHX3 [HugePedia]
snp3D : Map Gene to Disease23051
BioCentury BCIQZHX3
ClinGenZHX3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23051
Chemical/Pharm GKB GenePA38056
Clinical trialZHX3
Miscellaneous
canSAR (ICR)ZHX3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZHX3
EVEXZHX3
GoPubMedZHX3
iHOPZHX3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:52:24 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.