Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 7546
MIM: 603073
HGNC: 12873
Ensembl: ENSG00000043355
Variants:
dbSNP: 7546
ClinVar: 7546
TCGA: ENSG00000043355
COSMIC: ZIC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000043355 | ENST00000376335 | O95409 |
| ENSG00000043355 | ENST00000376335 | A0A024RDY6 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37479694 | 2023 | ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis. | 2 |
| 37496990 | 2023 | FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway. | 1 |
| 37774522 | 2023 | ZIC2 accelerates growth and stemness in gastric cancer through the Wnt/β-catenin pathway. | 0 |
| 37479694 | 2023 | ZIC2 induces pro-tumor macrophage polarization in nasopharyngeal carcinoma by activating the JUNB/MCSF axis. | 2 |
| 37496990 | 2023 | FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway. | 1 |
| 37774522 | 2023 | ZIC2 accelerates growth and stemness in gastric cancer through the Wnt/β-catenin pathway. | 0 |
| 35390314 | 2022 | ZIC2 promotes colorectal cancer growth and metastasis through the TGF-β signaling pathway. | 7 |
| 35390314 | 2022 | ZIC2 promotes colorectal cancer growth and metastasis through the TGF-β signaling pathway. | 7 |
| 32555352 | 2021 | The tumor-suppressive role of microRNA-873 in nasopharyngeal carcinoma correlates with downregulation of ZIC2 and inhibition of AKT signaling pathway. | 7 |
| 33439969 | 2021 | Correlation of zinc finger protein 2, a prognostic biomarker, with immune infiltrates in liver cancer. | 5 |
| 33557041 | 2021 | De Novo PORCN and ZIC2 Mutations in a Highly Consanguineous Family. | 4 |
| 34099631 | 2021 | Multilevel regulation of Wnt signaling by Zic2 in colon cancer due to mutation of β-catenin. | 5 |
| 34232917 | 2021 | Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis. | 11 |
| 34278490 | 2021 | ZIC2 upregulates lncRNA SNHG12 expression to promote endometrial cancer cell proliferation and migration by activating the Notch signaling pathway. | 5 |
| 32555352 | 2021 | The tumor-suppressive role of microRNA-873 in nasopharyngeal carcinoma correlates with downregulation of ZIC2 and inhibition of AKT signaling pathway. | 7 |
Citation
Dessen P
ZIC2 (Zic family member 2)
Atlas Genet Cytogenet Oncol Haematol. 2010-06-01
Online version: http://atlasgeneticsoncology.org/gene/51523/zic2
