Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ZIC2 (Zic family member 2)

Identity

Other namesHPE5
HGNC (Hugo) ZIC2
LocusID (NCBI) 7546
Location 13q32.3
Location_base_pair Starts at 100634026 and ends at 100639019 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)ZIC2   12873
Cards
Entrez_Gene (NCBI)ZIC2  7546  Zic family member 2
GeneCards (Weizmann)ZIC2
Ensembl hg19 (Hinxton)ENSG00000043355 [Gene_View]  chr13:100634026-100639019 [Contig_View]  ZIC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000043355 [Gene_View]  chr13:100634026-100639019 [Contig_View]  ZIC2 [Vega]
ICGC DataPortalENSG00000043355
cBioPortalZIC2
AceView (NCBI)ZIC2
Genatlas (Paris)ZIC2
WikiGenes7546
SOURCE (Princeton)ZIC2
Genomic and cartography
GoldenPath hg19 (UCSC)ZIC2  -     chr13:100634026-100639019 +  13q32.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZIC2  -     13q32.3   [Description]    (hg38-Dec_2013)
EnsemblZIC2 - 13q32.3 [CytoView hg19]  ZIC2 - 13q32.3 [CytoView hg38]
Mapping of homologs : NCBIZIC2 [Mapview hg19]  ZIC2 [Mapview hg38]
OMIM603073   609637   
Gene and transcription
Genbank (Entrez)AF104902 AF188733 AF193855 AF339806 BC172274
RefSeq transcript (Entrez)NM_007129
RefSeq genomic (Entrez)AC_000145 NC_000013 NC_018924 NG_007085 NT_009952 NW_001838084 NW_004929389
Consensus coding sequences : CCDS (NCBI)ZIC2
Cluster EST : UnigeneHs.653700 [ NCBI ]
CGAP (NCI)Hs.653700
Alternative Splicing : Fast-db (Paris)GSHG0008259
Alternative Splicing GalleryENSG00000043355
Gene ExpressionZIC2 [ NCBI-GEO ]     ZIC2 [ SEEK ]   ZIC2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95409 (Uniprot)
NextProtO95409  [Medical]
With graphics : InterProO95409
Splice isoforms : SwissVarO95409 (Swissvar)
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Related proteins : CluSTrO95409
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
DMDM Disease mutations7546
Blocks (Seattle)O95409
Human Protein AtlasENSG00000043355
Peptide AtlasO95409
HPRD04353
IPIIPI00030652   IPI00908526   IPI00872334   
Protein Interaction databases
DIP (DOE-UCLA)O95409
IntAct (EBI)O95409
FunCoupENSG00000043355
BioGRIDZIC2
IntegromeDBZIC2
STRING (EMBL)ZIC2
Ontologies - Pathways
QuickGOO95409
Ontology : AmiGOneural tube closure  DNA binding  sequence-specific DNA binding transcription factor activity  nucleus  cytoplasm  transcription, DNA-templated  brain development  visual perception  retinal ganglion cell axon guidance  chromatin DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  developmental pigmentation  positive regulation of sequence-specific DNA binding transcription factor activity  
Ontology : EGO-EBIneural tube closure  DNA binding  sequence-specific DNA binding transcription factor activity  nucleus  cytoplasm  transcription, DNA-templated  brain development  visual perception  retinal ganglion cell axon guidance  chromatin DNA binding  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  developmental pigmentation  positive regulation of sequence-specific DNA binding transcription factor activity  
Pathways : KEGGHedgehog signaling pathway   
Protein Interaction DatabaseZIC2
DoCM (Curated mutations)ZIC2
Wikipedia pathwaysZIC2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerZIC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZIC2
dbVarZIC2
ClinVarZIC2
1000_GenomesZIC2 
Exome Variant ServerZIC2
SNP (GeneSNP Utah)ZIC2
SNP : HGBaseZIC2
Genetic variants : HAPMAPZIC2
Genomic VariantsZIC2  ZIC2 [DGVbeta]
Mutations
ICGC Data PortalENSG00000043355 
Somatic Mutations in Cancer : COSMICZIC2 
CONAN: Copy Number AnalysisZIC2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)13:100634026-100639019
Mutations and Diseases : HGMDZIC2
OMIM603073    609637   
MedgenZIC2
NextProtO95409 [Medical]
GENETestsZIC2
Disease Genetic AssociationZIC2
Huge Navigator ZIC2 [HugePedia]  ZIC2 [HugeCancerGEM]
snp3D : Map Gene to Disease7546
DGIdb (Drug Gene Interaction db)ZIC2
General knowledge
Homologs : HomoloGeneZIC2
Homology/Alignments : Family Browser (UCSC)ZIC2
Phylogenetic Trees/Animal Genes : TreeFamZIC2
Chemical/Protein Interactions : CTD7546
Chemical/Pharm GKB GenePA37462
Clinical trialZIC2
Cancer Resource (Charite)ENSG00000043355
Other databases
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
CoreMineZIC2
GoPubMedZIC2
iHOPZIC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Dec 21 02:23:11 CET 2014
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