Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZMIZ1 (zinc finger MIZ-type containing 1)

Identity

Alias_namesRAI17
retinoic acid induced 17
Alias_symbol (synonym)RP11-519K18.1
KIAA1224
FLJ13541
hZIMP10
Zimp10
MIZ
Other aliasTRAFIP10
ZIMP10
HGNC (Hugo) ZMIZ1
LocusID (NCBI) 57178
Atlas_Id 50211
Location 10q22.3  [Link to chromosome band 10q22]
Location_base_pair Starts at 79069035 and ends at 79316528 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PITPNC1 (17q24.2) / ZMIZ1 (10q22.3)PPT2 (6p21.32) / ZMIZ1 (10q22.3)SCAF11 (12q12) / ZMIZ1 (10q22.3)
ZMIZ1 (10q22.3) / ABL1 (9q34.12)ZMIZ1 (10q22.3) / ANAPC2 (9q34.3)ZMIZ1 (10q22.3) / CDPF1 (22q13.31)
ZMIZ1 (10q22.3) / DHFR (5q14.1)ZMIZ1 (10q22.3) / NSMCE4A (10q26.13)ZMIZ1 (10q22.3) / ZMIZ1 (10q22.3)
ZMIZ1 10q22.3 C22orf40ZMIZ1 10q22.3 / NSMCE4A 10q26.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Protein

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;10)(q34;q22) ZMIZ1/ABL1


External links

Nomenclature
HGNC (Hugo)ZMIZ1   16493
Cards
Entrez_Gene (NCBI)ZMIZ1  57178  zinc finger MIZ-type containing 1
AliasesMIZ; RAI17; TRAFIP10; ZIMP10; 
hZIMP10
GeneCards (Weizmann)ZMIZ1
Ensembl hg19 (Hinxton)ENSG00000108175 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108175 [Gene_View]  chr10:79069035-79316528 [Contig_View]  ZMIZ1 [Vega]
ICGC DataPortalENSG00000108175
TCGA cBioPortalZMIZ1
AceView (NCBI)ZMIZ1
Genatlas (Paris)ZMIZ1
WikiGenes57178
SOURCE (Princeton)ZMIZ1
Genetics Home Reference (NIH)ZMIZ1
Genomic and cartography
GoldenPath hg38 (UCSC)ZMIZ1  -     chr10:79069035-79316528 +  10q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZMIZ1  -     10q22.3   [Description]    (hg19-Feb_2009)
EnsemblZMIZ1 - 10q22.3 [CytoView hg19]  ZMIZ1 - 10q22.3 [CytoView hg38]
Mapping of homologs : NCBIZMIZ1 [Mapview hg19]  ZMIZ1 [Mapview hg38]
OMIM607159   
Gene and transcription
Genbank (Entrez)AB033050 AF070622 AF357909 AK023603 AK024490
RefSeq transcript (Entrez)NM_020338
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZMIZ1
Cluster EST : UnigeneHs.193118 [ NCBI ]
CGAP (NCI)Hs.193118
Alternative Splicing GalleryENSG00000108175
Gene ExpressionZMIZ1 [ NCBI-GEO ]   ZMIZ1 [ EBI - ARRAY_EXPRESS ]   ZMIZ1 [ SEEK ]   ZMIZ1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZMIZ1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57178
GTEX Portal (Tissue expression)ZMIZ1
Human Protein AtlasENSG00000108175-ZMIZ1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULJ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULJ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULJ6
Splice isoforms : SwissVarQ9ULJ6
PhosPhoSitePlusQ9ULJ6
Domaine pattern : Prosite (Expaxy)ZF_SP_RING (PS51044)   
Domains : Interpro (EBI)Znf_MIZ    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-MIZ (PF02891)   
Domain families : Pfam (NCBI)pfam02891   
Conserved Domain (NCBI)ZMIZ1
DMDM Disease mutations57178
Blocks (Seattle)ZMIZ1
PDB (SRS)5AIZ   
PDB (PDBSum)5AIZ   
PDB (IMB)5AIZ   
PDB (RSDB)5AIZ   
Structural Biology KnowledgeBase5AIZ   
SCOP (Structural Classification of Proteins)5AIZ   
CATH (Classification of proteins structures)5AIZ   
SuperfamilyQ9ULJ6
Human Protein Atlas [tissue]ENSG00000108175-ZMIZ1 [tissue]
Peptide AtlasQ9ULJ6
HPRD12115
IPIIPI00176571   IPI01013319   IPI00908831   IPI00477110   IPI00784481   IPI00386305   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULJ6
IntAct (EBI)Q9ULJ6
FunCoupENSG00000108175
BioGRIDZMIZ1
STRING (EMBL)ZMIZ1
ZODIACZMIZ1
Ontologies - Pathways
QuickGOQ9ULJ6
Ontology : AmiGOvasculogenesis  in utero embryonic development  heart morphogenesis  nucleoplasm  cytoplasm  transcription, DNA-templated  vitellogenesis  cell aging  zinc ion binding  nuclear speck  intracellular membrane-bounded organelle  positive regulation of T cell differentiation  positive regulation of Notch signaling pathway  positive regulation of transcription from RNA polymerase II promoter  positive regulation of fibroblast proliferation  developmental growth  artery morphogenesis  
Ontology : EGO-EBIvasculogenesis  in utero embryonic development  heart morphogenesis  nucleoplasm  cytoplasm  transcription, DNA-templated  vitellogenesis  cell aging  zinc ion binding  nuclear speck  intracellular membrane-bounded organelle  positive regulation of T cell differentiation  positive regulation of Notch signaling pathway  positive regulation of transcription from RNA polymerase II promoter  positive regulation of fibroblast proliferation  developmental growth  artery morphogenesis  
NDEx NetworkZMIZ1
Atlas of Cancer Signalling NetworkZMIZ1
Wikipedia pathwaysZMIZ1
Orthology - Evolution
OrthoDB57178
GeneTree (enSembl)ENSG00000108175
Phylogenetic Trees/Animal Genes : TreeFamZMIZ1
HOVERGENQ9ULJ6
HOGENOMQ9ULJ6
Homologs : HomoloGeneZMIZ1
Homology/Alignments : Family Browser (UCSC)ZMIZ1
Gene fusions - Rearrangements
Fusion : MitelmanZMIZ1/ABL1 [10q22.3/9q34.12]  
Fusion : MitelmanZMIZ1/CDPF1 [10q22.3/22q13.31]  [t(10;22)(q22;q13)]  
Fusion : MitelmanZMIZ1/NSMCE4A [10q22.3/10q26.13]  [t(10;10)(q22;q26)]  
Fusion: TCGA_MDACCZMIZ1 10q22.3 C22orf40 BRCA
Fusion: TCGA_MDACCZMIZ1 10q22.3 NSMCE4A 10q26.13 BRCA
Tumor Fusion PortalZMIZ1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZMIZ1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZMIZ1
dbVarZMIZ1
ClinVarZMIZ1
1000_GenomesZMIZ1 
Exome Variant ServerZMIZ1
ExAC (Exome Aggregation Consortium)ENSG00000108175
GNOMAD BrowserENSG00000108175
Genetic variants : HAPMAP57178
Genomic Variants (DGV)ZMIZ1 [DGVbeta]
DECIPHERZMIZ1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZMIZ1 
Mutations
ICGC Data PortalZMIZ1 
TCGA Data PortalZMIZ1 
Broad Tumor PortalZMIZ1
OASIS PortalZMIZ1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZMIZ1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZMIZ1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZMIZ1
DgiDB (Drug Gene Interaction Database)ZMIZ1
DoCM (Curated mutations)ZMIZ1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZMIZ1 (select a term)
intoGenZMIZ1
Cancer3DZMIZ1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607159   
Orphanet
DisGeNETZMIZ1
MedgenZMIZ1
Genetic Testing Registry ZMIZ1
NextProtQ9ULJ6 [Medical]
TSGene57178
GENETestsZMIZ1
Target ValidationZMIZ1
Huge Navigator ZMIZ1 [HugePedia]
snp3D : Map Gene to Disease57178
BioCentury BCIQZMIZ1
ClinGenZMIZ1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57178
Chemical/Pharm GKB GenePA162409804
Clinical trialZMIZ1
Miscellaneous
canSAR (ICR)ZMIZ1 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZMIZ1
EVEXZMIZ1
GoPubMedZMIZ1
iHOPZMIZ1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:42:23 CET 2017

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