ZMYND11 (zinc finger MYND-type containing 11)

2014-05-01  

Identity

HGNC
LOCATION
10p15.3
LOCUSID
ALIAS
BRAM1,BS69,MRD30
FUSION GENES

Other Information

Locus ID:

NCBI: 10771
MIM: 608668
HGNC: 16966
Ensembl: ENSG00000015171

Variants:

dbSNP: 10771
ClinVar: 10771
TCGA: ENSG00000015171
COSMIC: ZMYND11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000015171ENST00000309776B7Z2J6
ENSG00000015171ENST00000381584J3QKD2
ENSG00000015171ENST00000381591Q15326
ENSG00000015171ENST00000381604A0A0A0MRY2
ENSG00000015171ENST00000381607Q15326
ENSG00000015171ENST00000397955E7EV75
ENSG00000015171ENST00000397959Q15326
ENSG00000015171ENST00000397962Q15326
ENSG00000015171ENST00000402736E7ENI9
ENSG00000015171ENST00000403354B0QZE2
ENSG00000015171ENST00000439456E9PE09
ENSG00000015171ENST00000509513Q15326
ENSG00000015171ENST00000558098Q15326
ENSG00000015171ENST00000602682Q15326
ENSG00000015171ENST00000627286J3QKD2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

References

Pubmed IDYearTitleCitations
245900752014ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression.103
252635942014BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.71
117335282002The conserved Mynd domain of BS69 binds cellular and oncoviral proteins through a common PXLXP motif.29
107343132000The adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoR.17
163821372006BS69, a specific adaptor in the latent membrane protein 1-mediated c-Jun N-terminal kinase pathway.13
165650762006New insights into BS69 functions.13
246755312014Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding.13
163007382006Ubiquitin-dependent degradation of adenovirus E1A protein is inhibited by BS69.7
281194152017Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.7
201381742010BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.6

Citation

Dessen P

ZMYND11 (zinc finger MYND-type containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53916/zmynd11