Written | 2000-10 | Gérard.Goubin |
Laboratoire d'Oncogenöse, UMR147 CNRS, Section de recherche, Institut Curie, Paris, France |
Identity |
Alias (NCBI) | OZF |
HGNC (Hugo) | ZNF146 |
HGNC Alias symb | OZF |
LocusID (NCBI) | 7705 |
Atlas_Id | 267 |
Location | 19q13.12 [Link to chromosome band 19q13] |
Location_base_pair | Starts at 36214602 and ends at 36238773 bp from pter ( according to GRCh38/hg38-Dec_2013) [Mapping ZNF146.png] |
Fusion genes (updated 2017) | Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands) |
ZNF146 (19q13.12) / NCAM2 (21q21.1) | ZNF146 (19q13.12) / UTP11 (1p34.3) |
Protein |
Description | 33 kDa; a kruppel zinc finger protein consisting of 10 zinc finger motives, preceeded by 10 amino acids and followed by 2 amino acids |
Expression | in most proliferating tissues |
Localisation | nucleus |
Function | represse gene expression through a consensus motive |
Implicated in |
Note | |
Disease | tumors of the exocrine pancreas |
Cytogenetics | amplification of the 19q13.1 region in a subset of pancreatic tumors |
Bibliography |
The OZF gene encodes a protein consisting essentially of zinc finger motifs. |
Le Chalony C, Prospéri MT, Haluza R, Apiou F, Dutrillaux B, Goubin G |
Journal of molecular biology. 1994 ; 236 (2) : 399-404. |
PMID 8107129 |
Citation |
This paper should be referenced as such : |
Goubin, G |
ZNF146 (zinc finger protein 146) |
Atlas Genet Cytogenet Oncol Haematol. 2000;4(4):197-197. |
Free journal version : [ pdf ] [ DOI ] |
External links |
REVIEW articles | automatic search in PubMed |
Last year publications | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Thu Mar 25 20:06:23 CET 2021 |
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