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ZNF174 (zinc finger protein 174)

Identity

Alias_symbol (synonym)ZSCAN8
Other alias
HGNC (Hugo) ZNF174
LocusID (NCBI) 7727
Atlas_Id 76008
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 3401190 and ends at 3405043 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF174   12963
Cards
Entrez_Gene (NCBI)ZNF174  7727  zinc finger protein 174
AliasesZSCAN8
GeneCards (Weizmann)ZNF174
Ensembl hg19 (Hinxton)ENSG00000103343 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103343 [Gene_View]  chr16:3401190-3405043 [Contig_View]  ZNF174 [Vega]
ICGC DataPortalENSG00000103343
TCGA cBioPortalZNF174
AceView (NCBI)ZNF174
Genatlas (Paris)ZNF174
WikiGenes7727
SOURCE (Princeton)ZNF174
Genetics Home Reference (NIH)ZNF174
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF174  -     chr16:3401190-3405043 +  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF174  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblZNF174 - 16p13.3 [CytoView hg19]  ZNF174 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIZNF174 [Mapview hg19]  ZNF174 [Mapview hg38]
OMIM603900   
Gene and transcription
Genbank (Entrez)AF542096 BC000876 BC001161 BI918471 BM969505
RefSeq transcript (Entrez)NM_001032292 NM_001347868 NM_001347869 NM_001347870 NM_003450
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF174
Cluster EST : UnigeneHs.155204 [ NCBI ]
CGAP (NCI)Hs.155204
Alternative Splicing GalleryENSG00000103343
Gene ExpressionZNF174 [ NCBI-GEO ]   ZNF174 [ EBI - ARRAY_EXPRESS ]   ZNF174 [ SEEK ]   ZNF174 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF174 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7727
GTEX Portal (Tissue expression)ZNF174
Human Protein AtlasENSG00000103343-ZNF174 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15697   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15697  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15697
Splice isoforms : SwissVarQ15697
PhosPhoSitePlusQ15697
Domaine pattern : Prosite (Expaxy)SCAN_BOX (PS50804)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)C2H2_Znf_fam    Retrov_capsid_C    SCAN_dom    Zfp174    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)SCAN (PF02023)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam02023    pfam00096   
Domain families : Smart (EMBL)SCAN (SM00431)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF174
DMDM Disease mutations7727
Blocks (Seattle)ZNF174
PDB (SRS)1Y7Q   
PDB (PDBSum)1Y7Q   
PDB (IMB)1Y7Q   
PDB (RSDB)1Y7Q   
Structural Biology KnowledgeBase1Y7Q   
SCOP (Structural Classification of Proteins)1Y7Q   
CATH (Classification of proteins structures)1Y7Q   
SuperfamilyQ15697
Human Protein Atlas [tissue]ENSG00000103343-ZNF174 [tissue]
Peptide AtlasQ15697
HPRD04876
IPIIPI00018955   IPI00029669   
Protein Interaction databases
DIP (DOE-UCLA)Q15697
IntAct (EBI)Q15697
FunCoupENSG00000103343
BioGRIDZNF174
STRING (EMBL)ZNF174
ZODIACZNF174
Ontologies - Pathways
QuickGOQ15697
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleus  nucleoplasm  cytosol  plasma membrane  transcription, DNA-templated  actin cytoskeleton  protein homodimerization activity  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleus  nucleoplasm  cytosol  plasma membrane  transcription, DNA-templated  actin cytoskeleton  protein homodimerization activity  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF174
Atlas of Cancer Signalling NetworkZNF174
Wikipedia pathwaysZNF174
Orthology - Evolution
OrthoDB7727
GeneTree (enSembl)ENSG00000103343
Phylogenetic Trees/Animal Genes : TreeFamZNF174
HOVERGENQ15697
HOGENOMQ15697
Homologs : HomoloGeneZNF174
Homology/Alignments : Family Browser (UCSC)ZNF174
Gene fusions - Rearrangements
Tumor Fusion PortalZNF174
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF174 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF174
dbVarZNF174
ClinVarZNF174
1000_GenomesZNF174 
Exome Variant ServerZNF174
ExAC (Exome Aggregation Consortium)ENSG00000103343
GNOMAD BrowserENSG00000103343
Genetic variants : HAPMAP7727
Genomic Variants (DGV)ZNF174 [DGVbeta]
DECIPHERZNF174 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF174 
Mutations
ICGC Data PortalZNF174 
TCGA Data PortalZNF174 
Broad Tumor PortalZNF174
OASIS PortalZNF174 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF174  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF174
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF174
DgiDB (Drug Gene Interaction Database)ZNF174
DoCM (Curated mutations)ZNF174 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF174 (select a term)
intoGenZNF174
Cancer3DZNF174(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603900   
Orphanet
DisGeNETZNF174
MedgenZNF174
Genetic Testing Registry ZNF174
NextProtQ15697 [Medical]
TSGene7727
GENETestsZNF174
Target ValidationZNF174
Huge Navigator ZNF174 [HugePedia]
snp3D : Map Gene to Disease7727
BioCentury BCIQZNF174
ClinGenZNF174
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7727
Chemical/Pharm GKB GenePA37545
Clinical trialZNF174
Miscellaneous
canSAR (ICR)ZNF174 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF174
EVEXZNF174
GoPubMedZNF174
iHOPZNF174
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:34:42 CET 2017

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