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ZNF254 (zinc finger protein 254)

Identity

Alias_namesZNF91L
ZNF539
zinc finger protein 539
Alias_symbol (synonym)HD-ZNF1
BMZF-5
Other alias
HGNC (Hugo) ZNF254
LocusID (NCBI) 9534
Atlas_Id 76055
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 24033405 and ends at 24129967 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CASC3 (17q21.1) / ZNF254 (19p12)ZNF141 (4p16.3) / ZNF254 (19p12)ZNF254 (19p12) / TTBK1 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF254   13047
Cards
Entrez_Gene (NCBI)ZNF254  9534  zinc finger protein 254
AliasesBMZF-5; HD-ZNF1; ZNF539; ZNF91L
GeneCards (Weizmann)ZNF254
Ensembl hg19 (Hinxton)ENSG00000213096 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213096 [Gene_View]  chr19:24033405-24129967 [Contig_View]  ZNF254 [Vega]
ICGC DataPortalENSG00000213096
TCGA cBioPortalZNF254
AceView (NCBI)ZNF254
Genatlas (Paris)ZNF254
WikiGenes9534
SOURCE (Princeton)ZNF254
Genetics Home Reference (NIH)ZNF254
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF254  -     chr19:24033405-24129967 +  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF254  -     19p12   [Description]    (hg19-Feb_2009)
EnsemblZNF254 - 19p12 [CytoView hg19]  ZNF254 - 19p12 [CytoView hg38]
Mapping of homologs : NCBIZNF254 [Mapview hg19]  ZNF254 [Mapview hg38]
OMIM604768   
Gene and transcription
Genbank (Entrez)AF054180 AK092080 AK092150 AK092820 AK291286
RefSeq transcript (Entrez)NM_001278661 NM_001278662 NM_001278663 NM_001278664 NM_001278665 NM_001278677 NM_001278678 NM_004876 NM_203282
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF254
Cluster EST : UnigeneHs.729302 [ NCBI ]
CGAP (NCI)Hs.729302
Alternative Splicing GalleryENSG00000213096
Gene ExpressionZNF254 [ NCBI-GEO ]   ZNF254 [ EBI - ARRAY_EXPRESS ]   ZNF254 [ SEEK ]   ZNF254 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF254 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9534
GTEX Portal (Tissue expression)ZNF254
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75437   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75437  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75437
Splice isoforms : SwissVarO75437
PhosPhoSitePlusO75437
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF254
DMDM Disease mutations9534
Blocks (Seattle)ZNF254
SuperfamilyO75437
Human Protein AtlasENSG00000213096
Peptide AtlasO75437
HPRD05304
IPIIPI00411674   IPI00871413   IPI01013634   IPI00384898   
Protein Interaction databases
DIP (DOE-UCLA)O75437
IntAct (EBI)O75437
FunCoupENSG00000213096
BioGRIDZNF254
STRING (EMBL)ZNF254
ZODIACZNF254
Ontologies - Pathways
QuickGOO75437
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF254
Atlas of Cancer Signalling NetworkZNF254
Wikipedia pathwaysZNF254
Orthology - Evolution
OrthoDB9534
GeneTree (enSembl)ENSG00000213096
Phylogenetic Trees/Animal Genes : TreeFamZNF254
HOVERGENO75437
HOGENOMO75437
Homologs : HomoloGeneZNF254
Homology/Alignments : Family Browser (UCSC)ZNF254
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF254 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF254
dbVarZNF254
ClinVarZNF254
1000_GenomesZNF254 
Exome Variant ServerZNF254
ExAC (Exome Aggregation Consortium)ZNF254 (select the gene name)
Genetic variants : HAPMAP9534
Genomic Variants (DGV)ZNF254 [DGVbeta]
DECIPHERZNF254 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF254 
Mutations
ICGC Data PortalZNF254 
TCGA Data PortalZNF254 
Broad Tumor PortalZNF254
OASIS PortalZNF254 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDZNF254
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF254
DgiDB (Drug Gene Interaction Database)ZNF254
DoCM (Curated mutations)ZNF254 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF254 (select a term)
intoGenZNF254
Cancer3DZNF254(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604768   
Orphanet
MedgenZNF254
Genetic Testing Registry ZNF254
NextProtO75437 [Medical]
TSGene9534
GENETestsZNF254
Target ValidationZNF254
Huge Navigator ZNF254 [HugePedia]
snp3D : Map Gene to Disease9534
BioCentury BCIQZNF254
ClinGenZNF254
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9534
Chemical/Pharm GKB GenePA37625
Clinical trialZNF254
Miscellaneous
canSAR (ICR)ZNF254 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF254
EVEXZNF254
GoPubMedZNF254
iHOPZNF254
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:50:07 CEST 2017

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