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ZNF254 (zinc finger protein 254)

Identity

Alias (NCBI)BMZF-5
HD-ZNF1
ZNF539
ZNF91L
HGNC (Hugo) ZNF254
HGNC Alias symbHD-ZNF1
BMZF-5
HGNC Previous nameZNF91L
 ZNF539
HGNC Previous namezinc finger protein 539
LocusID (NCBI) 9534
Atlas_Id 76055
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 24087187 and ends at 24129967 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CASC3 (17q21.1)::ZNF254 (19p12)ZNF141 (4p16.3)::ZNF254 (19p12)ZNF254 (19p12)::TTBK1 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF254   13047
Cards
Entrez_Gene (NCBI)ZNF254    zinc finger protein 254
AliasesBMZF-5; HD-ZNF1; ZNF539; ZNF91L
GeneCards (Weizmann)ZNF254
Ensembl hg19 (Hinxton)ENSG00000213096 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000213096 [Gene_View]  ENSG00000213096 [Sequence]  chr19:24087187-24129967 [Contig_View]  ZNF254 [Vega]
ICGC DataPortalENSG00000213096
TCGA cBioPortalZNF254
AceView (NCBI)ZNF254
Genatlas (Paris)ZNF254
SOURCE (Princeton)ZNF254
Genetics Home Reference (NIH)ZNF254
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF254  -     chr19:24087187-24129967 +  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF254  -     19p12   [Description]    (hg19-Feb_2009)
GoldenPathZNF254 - 19p12 [CytoView hg19]  ZNF254 - 19p12 [CytoView hg38]
ImmunoBaseENSG00000213096
Genome Data Viewer NCBIZNF254 [Mapview hg19]  
OMIM604768   
Gene and transcription
Genbank (Entrez)AF054180 AK092080 AK092150 AK092820 AK291286
RefSeq transcript (Entrez)NM_001278661 NM_001278662 NM_001278663 NM_001278664 NM_001278665 NM_001278677 NM_001278678 NM_004876 NM_203282
Consensus coding sequences : CCDS (NCBI)ZNF254
Gene ExpressionZNF254 [ NCBI-GEO ]   ZNF254 [ EBI - ARRAY_EXPRESS ]   ZNF254 [ SEEK ]   ZNF254 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF254 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF254 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9534
GTEX Portal (Tissue expression)ZNF254
Human Protein AtlasENSG00000213096-ZNF254 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75437   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75437  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75437
PhosPhoSitePlusO75437
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF254
SuperfamilyO75437
AlphaFold pdb e-kbO75437   
Human Protein Atlas [tissue]ENSG00000213096-ZNF254 [tissue]
HPRD05304
Protein Interaction databases
DIP (DOE-UCLA)O75437
IntAct (EBI)O75437
BioGRIDZNF254
STRING (EMBL)ZNF254
ZODIACZNF254
Ontologies - Pathways
QuickGOO75437
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF254
Atlas of Cancer Signalling NetworkZNF254
Wikipedia pathwaysZNF254
Orthology - Evolution
OrthoDB9534
GeneTree (enSembl)ENSG00000213096
Phylogenetic Trees/Animal Genes : TreeFamZNF254
Homologs : HomoloGeneZNF254
Homology/Alignments : Family Browser (UCSC)ZNF254
Gene fusions - Rearrangements
Fusion : QuiverZNF254
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF254 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF254
dbVarZNF254
ClinVarZNF254
MonarchZNF254
1000_GenomesZNF254 
Exome Variant ServerZNF254
GNOMAD BrowserENSG00000213096
Varsome BrowserZNF254
ACMGZNF254 variants
VarityO75437
Genomic Variants (DGV)ZNF254 [DGVbeta]
DECIPHERZNF254 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF254 
Mutations
ICGC Data PortalZNF254 
TCGA Data PortalZNF254 
Broad Tumor PortalZNF254
OASIS PortalZNF254 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF254  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF254
Mutations and Diseases : HGMDZNF254
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF254
DgiDB (Drug Gene Interaction Database)ZNF254
DoCM (Curated mutations)ZNF254
CIViC (Clinical Interpretations of Variants in Cancer)ZNF254
Cancer3DZNF254
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604768   
Orphanet
DisGeNETZNF254
MedgenZNF254
Genetic Testing Registry ZNF254
NextProtO75437 [Medical]
GENETestsZNF254
Target ValidationZNF254
Huge Navigator ZNF254 [HugePedia]
ClinGenZNF254
Clinical trials, drugs, therapy
MyCancerGenomeZNF254
Protein Interactions : CTDZNF254
Pharm GKB GenePA37625
PharosO75437
Clinical trialZNF254
Miscellaneous
canSAR (ICR)ZNF254
HarmonizomeZNF254
ARCHS4ZNF254
DataMed IndexZNF254
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF254
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 13:59:27 CET 2022

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