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ZNF268 (zinc finger protein 268)

Identity

Alias_symbol (synonym)HZF3
Other alias
HGNC (Hugo) ZNF268
LocusID (NCBI) 10795
Atlas_Id 53202
Location 12q24.33  [Link to chromosome band 12q24]
Location_base_pair Starts at 133181474 and ends at 133207111 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HBA2 (16p13.3) / ZNF268 (12q24.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF268   13061
Cards
Entrez_Gene (NCBI)ZNF268  10795  zinc finger protein 268
AliasesHZF3
GeneCards (Weizmann)ZNF268
Ensembl hg19 (Hinxton)ENSG00000090612 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000090612 [Gene_View]  chr12:133181474-133207111 [Contig_View]  ZNF268 [Vega]
ICGC DataPortalENSG00000090612
TCGA cBioPortalZNF268
AceView (NCBI)ZNF268
Genatlas (Paris)ZNF268
WikiGenes10795
SOURCE (Princeton)ZNF268
Genetics Home Reference (NIH)ZNF268
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF268  -     chr12:133181474-133207111 +  12q24.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF268  -     12q24.33   [Description]    (hg19-Feb_2009)
EnsemblZNF268 - 12q24.33 [CytoView hg19]  ZNF268 - 12q24.33 [CytoView hg38]
Mapping of homologs : NCBIZNF268 [Mapview hg19]  ZNF268 [Mapview hg38]
OMIM604753   
Gene and transcription
Genbank (Entrez)AF141655 AF317549 AF385187 AF432217 AK027712
RefSeq transcript (Entrez)NM_001165881 NM_001165882 NM_001165883 NM_001165884 NM_001165885 NM_001165886 NM_001165887 NM_003415 NM_152943
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF268
Cluster EST : UnigeneHs.124047 [ NCBI ]
CGAP (NCI)Hs.124047
Alternative Splicing GalleryENSG00000090612
Gene ExpressionZNF268 [ NCBI-GEO ]   ZNF268 [ EBI - ARRAY_EXPRESS ]   ZNF268 [ SEEK ]   ZNF268 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF268 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10795
GTEX Portal (Tissue expression)ZNF268
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14587   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14587  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14587
Splice isoforms : SwissVarQ14587
PhosPhoSitePlusQ14587
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF268
DMDM Disease mutations10795
Blocks (Seattle)ZNF268
PDB (SRS)2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
PDB (PDBSum)2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
PDB (IMB)2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
PDB (RSDB)2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
Structural Biology KnowledgeBase2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
SCOP (Structural Classification of Proteins)2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
CATH (Classification of proteins structures)2EL4    2EL5    2EL6    2EM1    2EMV    2EMW    2EMX    2EMY    2EN0    2EN6    2EN7    2EOF    2EOG    2EOI    2EOJ    2EOK    2EOL    2EOP    2EPV    2EPW    2EPY    2YTF    2YTQ   
SuperfamilyQ14587
Human Protein AtlasENSG00000090612
Peptide AtlasQ14587
HPRD05300
IPIIPI00031595   IPI01008774   IPI01009166   IPI00216187   IPI00946634   IPI00946482   IPI00946371   IPI01015545   IPI00945548   IPI00946843   IPI01011470   
Protein Interaction databases
DIP (DOE-UCLA)Q14587
IntAct (EBI)Q14587
FunCoupENSG00000090612
BioGRIDZNF268
STRING (EMBL)ZNF268
ZODIACZNF268
Ontologies - Pathways
QuickGOQ14587
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleus  cytoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of mitotic cell cycle  positive regulation of cell proliferation  negative regulation of cell proliferation  actin cytoskeleton  cell differentiation  positive regulation of cell migration  positive regulation of apoptotic process  negative regulation of apoptotic process  positive regulation of cell differentiation  positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle  metal ion binding  negative regulation of cell cycle arrest  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  transcription factor activity, sequence-specific DNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  nucleus  cytoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of mitotic cell cycle  positive regulation of cell proliferation  negative regulation of cell proliferation  actin cytoskeleton  cell differentiation  positive regulation of cell migration  positive regulation of apoptotic process  negative regulation of apoptotic process  positive regulation of cell differentiation  positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle  metal ion binding  negative regulation of cell cycle arrest  
NDEx NetworkZNF268
Atlas of Cancer Signalling NetworkZNF268
Wikipedia pathwaysZNF268
Orthology - Evolution
OrthoDB10795
GeneTree (enSembl)ENSG00000090612
Phylogenetic Trees/Animal Genes : TreeFamZNF268
HOVERGENQ14587
HOGENOMQ14587
Homologs : HomoloGeneZNF268
Homology/Alignments : Family Browser (UCSC)ZNF268
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF268 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF268
dbVarZNF268
ClinVarZNF268
1000_GenomesZNF268 
Exome Variant ServerZNF268
ExAC (Exome Aggregation Consortium)ZNF268 (select the gene name)
Genetic variants : HAPMAP10795
Genomic Variants (DGV)ZNF268 [DGVbeta]
DECIPHERZNF268 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF268 
Mutations
ICGC Data PortalZNF268 
TCGA Data PortalZNF268 
Broad Tumor PortalZNF268
OASIS PortalZNF268 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF268  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF268
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF268
DgiDB (Drug Gene Interaction Database)ZNF268
DoCM (Curated mutations)ZNF268 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF268 (select a term)
intoGenZNF268
Cancer3DZNF268(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604753   
Orphanet
MedgenZNF268
Genetic Testing Registry ZNF268
NextProtQ14587 [Medical]
TSGene10795
GENETestsZNF268
Target ValidationZNF268
Huge Navigator ZNF268 [HugePedia]
snp3D : Map Gene to Disease10795
BioCentury BCIQZNF268
ClinGenZNF268
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10795
Chemical/Pharm GKB GenePA37639
Clinical trialZNF268
Miscellaneous
canSAR (ICR)ZNF268 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF268
EVEXZNF268
GoPubMedZNF268
iHOPZNF268
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:42 CEST 2017

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