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ZNF276 (zinc finger protein 276)

Identity

Alias (NCBI)CENP-Z
CENPZ
ZADT
ZFP276
ZNF477
HGNC (Hugo) ZNF276
HGNC Alias symbMGC45417
ZNF477
CENPZ
CENP-Z
ZADT
HGNC Alias namecentromere protein Z
 zinc finger, AD-type
HGNC Previous nameZFP276
HGNC Previous namezinc finger protein 276 homolog (mouse)
LocusID (NCBI) 92822
Atlas_Id 76068
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 89720985 and ends at 89740924 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EXD3 (9q34.3) / ZNF276 (16q24.3)TNF (6p21.33) / ZNF276 (16q24.3)ZNF276 (16q24.3) / DHCR24 (1p32.3)
ZNF276 (16q24.3) / JPH3 (16q24.2)ZNF276 (16q24.3) / ZNF282 (7q36.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(9;16)(p13;q24) PAX5/ZNF276
t(9;16)(p13;q24) PAX5/ZNF276


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  ZNF276/JPH3 (16q24)


External links

Nomenclature
HGNC (Hugo)ZNF276   23330
Cards
Entrez_Gene (NCBI)ZNF276    zinc finger protein 276
AliasesCENP-Z; CENPZ; ZADT; ZFP276; 
ZNF477
GeneCards (Weizmann)ZNF276
Ensembl hg19 (Hinxton)ENSG00000158805 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158805 [Gene_View]  ENSG00000158805 [Sequence]  chr16:89720985-89740924 [Contig_View]  ZNF276 [Vega]
ICGC DataPortalENSG00000158805
TCGA cBioPortalZNF276
AceView (NCBI)ZNF276
Genatlas (Paris)ZNF276
SOURCE (Princeton)ZNF276
Genetics Home Reference (NIH)ZNF276
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF276  -     chr16:89720985-89740924 +  16q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF276  -     16q24.3   [Description]    (hg19-Feb_2009)
GoldenPathZNF276 - 16q24.3 [CytoView hg19]  ZNF276 - 16q24.3 [CytoView hg38]
ImmunoBaseENSG00000158805
genome Data Viewer NCBIZNF276 [Mapview hg19]  
OMIM608460   
Gene and transcription
Genbank (Entrez)AI283548 AK026482 AK056405 AK096004 AK096762
RefSeq transcript (Entrez)NM_001113525 NM_152287
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF276
Alternative Splicing GalleryENSG00000158805
Gene ExpressionZNF276 [ NCBI-GEO ]   ZNF276 [ EBI - ARRAY_EXPRESS ]   ZNF276 [ SEEK ]   ZNF276 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF276 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF276 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92822
GTEX Portal (Tissue expression)ZNF276
Human Protein AtlasENSG00000158805-ZNF276 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N554   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N554  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N554
Splice isoforms : SwissVarQ8N554
PhosPhoSitePlusQ8N554
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_AD    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)zf-AD (PF07776)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam07776    pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF276
Blocks (Seattle)ZNF276
SuperfamilyQ8N554
Human Protein Atlas [tissue]ENSG00000158805-ZNF276 [tissue]
Peptide AtlasQ8N554
HPRD12235
IPIIPI00847391   IPI00655817   IPI00641539   IPI00640333   
Protein Interaction databases
DIP (DOE-UCLA)Q8N554
IntAct (EBI)Q8N554
BioGRIDZNF276
STRING (EMBL)ZNF276
ZODIACZNF276
Ontologies - Pathways
QuickGOQ8N554
Ontology : AmiGOkinetochore  condensed chromosome kinetochore  DNA binding  protein binding  nucleus  zinc ion binding  
Ontology : EGO-EBIkinetochore  condensed chromosome kinetochore  DNA binding  protein binding  nucleus  zinc ion binding  
NDEx NetworkZNF276
Atlas of Cancer Signalling NetworkZNF276
Wikipedia pathwaysZNF276
Orthology - Evolution
OrthoDB92822
GeneTree (enSembl)ENSG00000158805
Phylogenetic Trees/Animal Genes : TreeFamZNF276
HOGENOMQ8N554
Homologs : HomoloGeneZNF276
Homology/Alignments : Family Browser (UCSC)ZNF276
Gene fusions - Rearrangements
Fusion : QuiverZNF276
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF276 [hg38]
dbVarZNF276
ClinVarZNF276
MonarchZNF276
1000_GenomesZNF276 
Exome Variant ServerZNF276
GNOMAD BrowserENSG00000158805
Varsome BrowserZNF276
Genomic Variants (DGV)ZNF276 [DGVbeta]
DECIPHERZNF276 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF276 
Mutations
ICGC Data PortalZNF276 
TCGA Data PortalZNF276 
Broad Tumor PortalZNF276
OASIS PortalZNF276 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF276  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF276
Mutations and Diseases : HGMDZNF276
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF276
DgiDB (Drug Gene Interaction Database)ZNF276
DoCM (Curated mutations)ZNF276 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF276 (select a term)
intoGenZNF276
Cancer3DZNF276(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608460   
Orphanet
DisGeNETZNF276
MedgenZNF276
Genetic Testing Registry ZNF276
NextProtQ8N554 [Medical]
GENETestsZNF276
Target ValidationZNF276
Huge Navigator ZNF276 [HugePedia]
ClinGenZNF276
Clinical trials, drugs, therapy
MyCancerGenomeZNF276
Protein Interactions : CTD
Pharm GKB GenePA134935042
Clinical trialZNF276
Miscellaneous
canSAR (ICR)ZNF276 (select the gene name)
HarmonizomeZNF276
DataMed IndexZNF276
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF276
EVEXZNF276
GoPubMedZNF276
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:35:49 CET 2020

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