Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZNF281 (zinc finger protein 281)

Identity

Alias (NCBI)GZP1
ZBP-99
ZBP99
ZNP-99
HGNC (Hugo) ZNF281
HGNC Alias symbZBP-99
LocusID (NCBI) 23528
Atlas_Id 53710
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 200404951 and ends at 200410036 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZNF281 (1q32.1)::SFTPB (2p11.2)ZNF281 (1q32.1)::ZNF281 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF281   13075
Cards
Entrez_Gene (NCBI)ZNF281    zinc finger protein 281
AliasesGZP1; ZBP-99; ZBP99; ZNP-99
GeneCards (Weizmann)ZNF281
Ensembl hg19 (Hinxton)ENSG00000162702 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162702 [Gene_View]  ENSG00000162702 [Sequence]  chr1:200404951-200410036 [Contig_View]  ZNF281 [Vega]
ICGC DataPortalENSG00000162702
TCGA cBioPortalZNF281
AceView (NCBI)ZNF281
Genatlas (Paris)ZNF281
SOURCE (Princeton)ZNF281
Genetics Home Reference (NIH)ZNF281
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF281  -     chr1:200404951-200410036 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF281  -     1q32.1   [Description]    (hg19-Feb_2009)
GoldenPathZNF281 - 1q32.1 [CytoView hg19]  ZNF281 - 1q32.1 [CytoView hg38]
ImmunoBaseENSG00000162702
Genome Data Viewer NCBIZNF281 [Mapview hg19]  
OMIM618703   
Gene and transcription
Genbank (Entrez)AF086540 AF125158 AJ132591 AJ132592 AK021707
RefSeq transcript (Entrez)NM_001281293 NM_001281294 NM_012482
Consensus coding sequences : CCDS (NCBI)ZNF281
Gene ExpressionZNF281 [ NCBI-GEO ]   ZNF281 [ EBI - ARRAY_EXPRESS ]   ZNF281 [ SEEK ]   ZNF281 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF281 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF281 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23528
GTEX Portal (Tissue expression)ZNF281
Human Protein AtlasENSG00000162702-ZNF281 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2X9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2X9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2X9
PhosPhoSitePlusQ9Y2X9
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam00096   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF281
SuperfamilyQ9Y2X9
AlphaFold pdb e-kbQ9Y2X9   
Human Protein Atlas [tissue]ENSG00000162702-ZNF281 [tissue]
HPRD11702
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2X9
IntAct (EBI)Q9Y2X9
BioGRIDZNF281
STRING (EMBL)ZNF281
ZODIACZNF281
Ontologies - Pathways
QuickGOQ9Y2X9
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  transcription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  embryonic body morphogenesis  negative regulation of gene expression  negative regulation of gene expression  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  stem cell differentiation  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  transcription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  embryonic body morphogenesis  negative regulation of gene expression  negative regulation of gene expression  sequence-specific DNA binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  stem cell differentiation  sequence-specific double-stranded DNA binding  
NDEx NetworkZNF281
Atlas of Cancer Signalling NetworkZNF281
Wikipedia pathwaysZNF281
Orthology - Evolution
OrthoDB23528
GeneTree (enSembl)ENSG00000162702
Phylogenetic Trees/Animal Genes : TreeFamZNF281
Homologs : HomoloGeneZNF281
Homology/Alignments : Family Browser (UCSC)ZNF281
Gene fusions - Rearrangements
Fusion Cancer (Beijing)ZNF281 [1q32.1]  -  SFTPB [2p11.2]  [FUSC003310]
Fusion : QuiverZNF281
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF281 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF281
dbVarZNF281
ClinVarZNF281
MonarchZNF281
1000_GenomesZNF281 
Exome Variant ServerZNF281
GNOMAD BrowserENSG00000162702
Varsome BrowserZNF281
ACMGZNF281 variants
VarityQ9Y2X9
Genomic Variants (DGV)ZNF281 [DGVbeta]
DECIPHERZNF281 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF281 
Mutations
ICGC Data PortalZNF281 
TCGA Data PortalZNF281 
Broad Tumor PortalZNF281
OASIS PortalZNF281 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF281  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF281
Mutations and Diseases : HGMDZNF281
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF281
DgiDB (Drug Gene Interaction Database)ZNF281
DoCM (Curated mutations)ZNF281
CIViC (Clinical Interpretations of Variants in Cancer)ZNF281
Cancer3DZNF281
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618703   
Orphanet
DisGeNETZNF281
MedgenZNF281
Genetic Testing Registry ZNF281
NextProtQ9Y2X9 [Medical]
GENETestsZNF281
Target ValidationZNF281
Huge Navigator ZNF281 [HugePedia]
ClinGenZNF281
Clinical trials, drugs, therapy
MyCancerGenomeZNF281
Protein Interactions : CTDZNF281
Pharm GKB GenePA37651
PharosQ9Y2X9
Clinical trialZNF281
Miscellaneous
canSAR (ICR)ZNF281
HarmonizomeZNF281
ARCHS4ZNF281
DataMed IndexZNF281
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF281
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sun Jan 16 18:41:38 CET 2022

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