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ZNF281 (zinc finger protein 281)

Identity

Alias_symbol (synonym)ZBP-99
Other aliasZNP-99
HGNC (Hugo) ZNF281
LocusID (NCBI) 23528
Atlas_Id 53710
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 200404947 and ends at 200410058 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ZNF281 (1q32.1) / SFTPB (2p11.2)ZNF281 (1q32.1) / ZNF281 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF281   13075
Cards
Entrez_Gene (NCBI)ZNF281  23528  zinc finger protein 281
AliasesZBP-99; ZNP-99
GeneCards (Weizmann)ZNF281
Ensembl hg19 (Hinxton)ENSG00000162702 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162702 [Gene_View]  chr1:200404947-200410058 [Contig_View]  ZNF281 [Vega]
ICGC DataPortalENSG00000162702
TCGA cBioPortalZNF281
AceView (NCBI)ZNF281
Genatlas (Paris)ZNF281
WikiGenes23528
SOURCE (Princeton)ZNF281
Genetics Home Reference (NIH)ZNF281
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF281  -     chr1:200404947-200410058 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF281  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblZNF281 - 1q32.1 [CytoView hg19]  ZNF281 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIZNF281 [Mapview hg19]  ZNF281 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF086540 AF125158 AJ132591 AJ132592 AK021707
RefSeq transcript (Entrez)NM_001281293 NM_001281294 NM_012482
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF281
Cluster EST : UnigeneHs.735801 [ NCBI ]
CGAP (NCI)Hs.735801
Alternative Splicing GalleryENSG00000162702
Gene ExpressionZNF281 [ NCBI-GEO ]   ZNF281 [ EBI - ARRAY_EXPRESS ]   ZNF281 [ SEEK ]   ZNF281 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF281 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23528
GTEX Portal (Tissue expression)ZNF281
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2X9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2X9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2X9
Splice isoforms : SwissVarQ9Y2X9
PhosPhoSitePlusQ9Y2X9
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF281
DMDM Disease mutations23528
Blocks (Seattle)ZNF281
SuperfamilyQ9Y2X9
Human Protein AtlasENSG00000162702
Peptide AtlasQ9Y2X9
HPRD11702
IPIIPI00032563   IPI00647664   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2X9
IntAct (EBI)Q9Y2X9
FunCoupENSG00000162702
BioGRIDZNF281
STRING (EMBL)ZNF281
ZODIACZNF281
Ontologies - Pathways
QuickGOQ9Y2X9
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  embryonic body morphogenesis  negative regulation of gene expression  negative regulation of gene expression  sequence-specific DNA binding  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  stem cell differentiation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  core promoter binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcription factor activity, sequence-specific DNA binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  embryonic body morphogenesis  negative regulation of gene expression  negative regulation of gene expression  sequence-specific DNA binding  transcription regulatory region DNA binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  stem cell differentiation  
NDEx NetworkZNF281
Atlas of Cancer Signalling NetworkZNF281
Wikipedia pathwaysZNF281
Orthology - Evolution
OrthoDB23528
GeneTree (enSembl)ENSG00000162702
Phylogenetic Trees/Animal Genes : TreeFamZNF281
HOVERGENQ9Y2X9
HOGENOMQ9Y2X9
Homologs : HomoloGeneZNF281
Homology/Alignments : Family Browser (UCSC)ZNF281
Gene fusions - Rearrangements
Fusion Cancer (Beijing)ZNF281 [1q32.1]  -  SFTPB [2p11.2]  [FUSC003310]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF281 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF281
dbVarZNF281
ClinVarZNF281
1000_GenomesZNF281 
Exome Variant ServerZNF281
ExAC (Exome Aggregation Consortium)ZNF281 (select the gene name)
Genetic variants : HAPMAP23528
Genomic Variants (DGV)ZNF281 [DGVbeta]
DECIPHERZNF281 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF281 
Mutations
ICGC Data PortalZNF281 
TCGA Data PortalZNF281 
Broad Tumor PortalZNF281
OASIS PortalZNF281 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF281  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF281
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF281
DgiDB (Drug Gene Interaction Database)ZNF281
DoCM (Curated mutations)ZNF281 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF281 (select a term)
intoGenZNF281
Cancer3DZNF281(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF281
Genetic Testing Registry ZNF281
NextProtQ9Y2X9 [Medical]
TSGene23528
GENETestsZNF281
Target ValidationZNF281
Huge Navigator ZNF281 [HugePedia]
snp3D : Map Gene to Disease23528
BioCentury BCIQZNF281
ClinGenZNF281
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23528
Chemical/Pharm GKB GenePA37651
Clinical trialZNF281
Miscellaneous
canSAR (ICR)ZNF281 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF281
EVEXZNF281
GoPubMedZNF281
iHOPZNF281
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:43 CEST 2017

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