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ZNF335 (zinc finger protein 335)

Identity

Alias (NCBI)MCPH10
NIF-1
NIF1
NIF2
HGNC (Hugo) ZNF335
HGNC Alias symbbA465L10.2
NIF-1
HGNC Alias nameNRC-interacting factor 1
LocusID (NCBI) 63925
Atlas_Id 53881
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 45948660 and ends at 45972203 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PGD (1p36.22) / ZNF335 (20q13.12)ZNF335 (20q13.12) / MYO1F (19p13.2)ZNF335 (20q13.12) / VPS25 (17q21.31)
ZNF335 (20q13.12) / ZSWIM3 (20q13.12)ZNF335 20q13.12 / ZSWIM3 20q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF335   15807
Cards
Entrez_Gene (NCBI)ZNF335    zinc finger protein 335
AliasesMCPH10; NIF-1; NIF1; NIF2
GeneCards (Weizmann)ZNF335
Ensembl hg19 (Hinxton)ENSG00000198026 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198026 [Gene_View]  ENSG00000198026 [Sequence]  chr20:45948660-45972203 [Contig_View]  ZNF335 [Vega]
ICGC DataPortalENSG00000198026
TCGA cBioPortalZNF335
AceView (NCBI)ZNF335
Genatlas (Paris)ZNF335
SOURCE (Princeton)ZNF335
Genetics Home Reference (NIH)ZNF335
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF335  -     chr20:45948660-45972203 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF335  -     20q13.12   [Description]    (hg19-Feb_2009)
GoldenPathZNF335 - 20q13.12 [CytoView hg19]  ZNF335 - 20q13.12 [CytoView hg38]
ImmunoBaseENSG00000198026
Genome Data Viewer NCBIZNF335 [Mapview hg19]  
OMIM610827   615095   
Gene and transcription
Genbank (Entrez)AF395833 AK026157 AK027358 AK054694 AK074214
RefSeq transcript (Entrez)NM_022095
Consensus coding sequences : CCDS (NCBI)ZNF335
Gene ExpressionZNF335 [ NCBI-GEO ]   ZNF335 [ EBI - ARRAY_EXPRESS ]   ZNF335 [ SEEK ]   ZNF335 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF335 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF335 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63925
GTEX Portal (Tissue expression)ZNF335
Human Protein AtlasENSG00000198026-ZNF335 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4Z2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4Z2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4Z2
PhosPhoSitePlusQ9H4Z2
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF335
SuperfamilyQ9H4Z2
AlphaFold pdb e-kbQ9H4Z2   
Human Protein Atlas [tissue]ENSG00000198026-ZNF335 [tissue]
HPRD11709
Protein Interaction databases
DIP (DOE-UCLA)Q9H4Z2
IntAct (EBI)Q9H4Z2
BioGRIDZNF335
STRING (EMBL)ZNF335
ZODIACZNF335
Ontologies - Pathways
QuickGOQ9H4Z2
Ontology : AmiGOtranscription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  in utero embryonic development  positive regulation of neuroblast proliferation  protein binding  nucleus  nucleus  nucleoplasm  brain development  brain development  regulation of gene expression  cerebral cortex neuron differentiation  regulation of gene expression, epigenetic  positive regulation of transcription by RNA polymerase II  metal ion binding  neuron projection morphogenesis  brain morphogenesis  positive regulation of lymphocyte proliferation  positive regulation of neurogenesis  positive regulation of neurogenesis  regulation of histone H3-K4 methylation  histone H3-K4 trimethylation  histone H3-K4 trimethylation  
Ontology : EGO-EBItranscription cis-regulatory region binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  in utero embryonic development  positive regulation of neuroblast proliferation  protein binding  nucleus  nucleus  nucleoplasm  brain development  brain development  regulation of gene expression  cerebral cortex neuron differentiation  regulation of gene expression, epigenetic  positive regulation of transcription by RNA polymerase II  metal ion binding  neuron projection morphogenesis  brain morphogenesis  positive regulation of lymphocyte proliferation  positive regulation of neurogenesis  positive regulation of neurogenesis  regulation of histone H3-K4 methylation  histone H3-K4 trimethylation  histone H3-K4 trimethylation  
NDEx NetworkZNF335
Atlas of Cancer Signalling NetworkZNF335
Wikipedia pathwaysZNF335
Orthology - Evolution
OrthoDB63925
GeneTree (enSembl)ENSG00000198026
Phylogenetic Trees/Animal Genes : TreeFamZNF335
Homologs : HomoloGeneZNF335
Homology/Alignments : Family Browser (UCSC)ZNF335
Gene fusions - Rearrangements
Fusion : MitelmanZNF335/ZSWIM3 [20q13.12/20q13.12]  
Fusion : QuiverZNF335
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF335 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF335
dbVarZNF335
ClinVarZNF335
MonarchZNF335
1000_GenomesZNF335 
Exome Variant ServerZNF335
GNOMAD BrowserENSG00000198026
Varsome BrowserZNF335
ACMGZNF335 variants
VarityQ9H4Z2
Genomic Variants (DGV)ZNF335 [DGVbeta]
DECIPHERZNF335 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF335 
Mutations
ICGC Data PortalZNF335 
TCGA Data PortalZNF335 
Broad Tumor PortalZNF335
OASIS PortalZNF335 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF335  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF335
Mutations and Diseases : HGMDZNF335
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF335
DgiDB (Drug Gene Interaction Database)ZNF335
DoCM (Curated mutations)ZNF335
CIViC (Clinical Interpretations of Variants in Cancer)ZNF335
Cancer3DZNF335
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610827    615095   
Orphanet21911   
DisGeNETZNF335
MedgenZNF335
Genetic Testing Registry ZNF335
NextProtQ9H4Z2 [Medical]
GENETestsZNF335
Target ValidationZNF335
Huge Navigator ZNF335 [HugePedia]
ClinGenZNF335
Clinical trials, drugs, therapy
MyCancerGenomeZNF335
Protein Interactions : CTDZNF335
Pharm GKB GenePA38041
PharosQ9H4Z2
Clinical trialZNF335
Miscellaneous
canSAR (ICR)ZNF335
HarmonizomeZNF335
DataMed IndexZNF335
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF335
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:39:14 CEST 2021

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