Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZNF335 (zinc finger protein 335)

Identity

Alias_symbol (synonym)bA465L10.2
NIF-1
Other aliasMCPH10
NIF1
NIF2
HGNC (Hugo) ZNF335
LocusID (NCBI) 63925
Atlas_Id 53881
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 44577292 and ends at 44600833 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PGD (1p36.22) / ZNF335 (20q13.12)ZNF335 (20q13.12) / MYO1F (19p13.2)ZNF335 (20q13.12) / VPS25 (17q21.31)
ZNF335 (20q13.12) / ZSWIM3 (20q13.12)ZNF335 20q13.12 / ZSWIM3 20q13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF335   15807
Cards
Entrez_Gene (NCBI)ZNF335  63925  zinc finger protein 335
AliasesMCPH10; NIF-1; NIF1; NIF2
GeneCards (Weizmann)ZNF335
Ensembl hg19 (Hinxton)ENSG00000198026 [Gene_View]  chr20:44577292-44600833 [Contig_View]  ZNF335 [Vega]
Ensembl hg38 (Hinxton)ENSG00000198026 [Gene_View]  chr20:44577292-44600833 [Contig_View]  ZNF335 [Vega]
ICGC DataPortalENSG00000198026
TCGA cBioPortalZNF335
AceView (NCBI)ZNF335
Genatlas (Paris)ZNF335
WikiGenes63925
SOURCE (Princeton)ZNF335
Genetics Home Reference (NIH)ZNF335
Genomic and cartography
GoldenPath hg19 (UCSC)ZNF335  -     chr20:44577292-44600833 -  20q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZNF335  -     20q13.12   [Description]    (hg38-Dec_2013)
EnsemblZNF335 - 20q13.12 [CytoView hg19]  ZNF335 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBIZNF335 [Mapview hg19]  ZNF335 [Mapview hg38]
OMIM610827   615095   
Gene and transcription
Genbank (Entrez)AF395833 AK026157 AK027358 AK054694 AK074214
RefSeq transcript (Entrez)NM_022095
RefSeq genomic (Entrez)NC_000020 NC_018931 NG_029772 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)ZNF335
Cluster EST : UnigeneHs.174193 [ NCBI ]
CGAP (NCI)Hs.174193
Alternative Splicing GalleryENSG00000198026
Gene ExpressionZNF335 [ NCBI-GEO ]   ZNF335 [ EBI - ARRAY_EXPRESS ]   ZNF335 [ SEEK ]   ZNF335 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF335 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63925
GTEX Portal (Tissue expression)ZNF335
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H4Z2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H4Z2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H4Z2
Splice isoforms : SwissVarQ9H4Z2
PhosPhoSitePlusQ9H4Z2
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF335
DMDM Disease mutations63925
Blocks (Seattle)ZNF335
SuperfamilyQ9H4Z2
Human Protein AtlasENSG00000198026
Peptide AtlasQ9H4Z2
HPRD11709
IPIIPI00021362   IPI00915023   IPI00181856   
Protein Interaction databases
DIP (DOE-UCLA)Q9H4Z2
IntAct (EBI)Q9H4Z2
FunCoupENSG00000198026
BioGRIDZNF335
STRING (EMBL)ZNF335
ZODIACZNF335
Ontologies - Pathways
QuickGOQ9H4Z2
Ontology : AmiGORNA polymerase II core promoter sequence-specific DNA binding  in utero embryonic development  positive regulation of neuroblast proliferation  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  brain development  cerebral cortex neuron differentiation  histone methyltransferase complex  regulation of gene expression, epigenetic  transcription regulatory region DNA binding  metal ion binding  neuron projection morphogenesis  brain morphogenesis  positive regulation of lymphocyte proliferation  positive regulation of neurogenesis  regulation of histone H3-K4 methylation  histone H3-K4 trimethylation  
Ontology : EGO-EBIRNA polymerase II core promoter sequence-specific DNA binding  in utero embryonic development  positive regulation of neuroblast proliferation  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  brain development  cerebral cortex neuron differentiation  histone methyltransferase complex  regulation of gene expression, epigenetic  transcription regulatory region DNA binding  metal ion binding  neuron projection morphogenesis  brain morphogenesis  positive regulation of lymphocyte proliferation  positive regulation of neurogenesis  regulation of histone H3-K4 methylation  histone H3-K4 trimethylation  
NDEx NetworkZNF335
Atlas of Cancer Signalling NetworkZNF335
Wikipedia pathwaysZNF335
Orthology - Evolution
OrthoDB63925
GeneTree (enSembl)ENSG00000198026
Phylogenetic Trees/Animal Genes : TreeFamZNF335
HOVERGENQ9H4Z2
HOGENOMQ9H4Z2
Homologs : HomoloGeneZNF335
Homology/Alignments : Family Browser (UCSC)ZNF335
Gene fusions - Rearrangements
Fusion : MitelmanZNF335/ZSWIM3 [20q13.12/20q13.12]  
Fusion: TCGAZNF335 20q13.12 ZSWIM3 20q13.12 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF335 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF335
dbVarZNF335
ClinVarZNF335
1000_GenomesZNF335 
Exome Variant ServerZNF335
ExAC (Exome Aggregation Consortium)ZNF335 (select the gene name)
Genetic variants : HAPMAP63925
Genomic Variants (DGV)ZNF335 [DGVbeta]
DECIPHER (Syndromes)20:44577292-44600833  ENSG00000198026
CONAN: Copy Number AnalysisZNF335 
Mutations
ICGC Data PortalZNF335 
TCGA Data PortalZNF335 
Broad Tumor PortalZNF335
OASIS PortalZNF335 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF335  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF335
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF335
DgiDB (Drug Gene Interaction Database)ZNF335
DoCM (Curated mutations)ZNF335 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF335 (select a term)
intoGenZNF335
Cancer3DZNF335(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610827    615095   
Orphanet21911   
MedgenZNF335
Genetic Testing Registry ZNF335
NextProtQ9H4Z2 [Medical]
TSGene63925
GENETestsZNF335
Huge Navigator ZNF335 [HugePedia]
snp3D : Map Gene to Disease63925
BioCentury BCIQZNF335
ClinGenZNF335
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63925
Chemical/Pharm GKB GenePA38041
Clinical trialZNF335
Miscellaneous
canSAR (ICR)ZNF335 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF335
EVEXZNF335
GoPubMedZNF335
iHOPZNF335
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:25:44 CEST 2017

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