Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZNF385A (zinc finger protein 385A)

Identity

Alias_namesZNF385
zinc finger protein 385
Alias_symbol (synonym)DKFZp586G1122
Hzf
ZFP385
Other aliasHZF
RZF
HGNC (Hugo) ZNF385A
LocusID (NCBI) 25946
Atlas_Id 76127
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 54369129 and ends at 54391305 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MRE11A (11q21) / ZNF385A (12q13.13)REV1 (2q11.2) / ZNF385A (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF385A   17521
Cards
Entrez_Gene (NCBI)ZNF385A  25946  zinc finger protein 385A
AliasesHZF; RZF; ZFP385; ZNF385
GeneCards (Weizmann)ZNF385A
Ensembl hg19 (Hinxton)ENSG00000161642 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161642 [Gene_View]  chr12:54369129-54391305 [Contig_View]  ZNF385A [Vega]
ICGC DataPortalENSG00000161642
TCGA cBioPortalZNF385A
AceView (NCBI)ZNF385A
Genatlas (Paris)ZNF385A
WikiGenes25946
SOURCE (Princeton)ZNF385A
Genetics Home Reference (NIH)ZNF385A
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF385A  -     chr12:54369129-54391305 -  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF385A  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblZNF385A - 12q13.13 [CytoView hg19]  ZNF385A - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIZNF385A [Mapview hg19]  ZNF385A [Mapview hg38]
OMIM609124   
Gene and transcription
Genbank (Entrez)AB593085 AF304052 AK024404 AK092724 AK296564
RefSeq transcript (Entrez)NM_001130967 NM_001130968 NM_001290001 NM_001290002 NM_001290004 NM_015481
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF385A
Cluster EST : UnigeneHs.505653 [ NCBI ]
CGAP (NCI)Hs.505653
Alternative Splicing GalleryENSG00000161642
Gene ExpressionZNF385A [ NCBI-GEO ]   ZNF385A [ EBI - ARRAY_EXPRESS ]   ZNF385A [ SEEK ]   ZNF385A [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF385A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25946
GTEX Portal (Tissue expression)ZNF385A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PM9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PM9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PM9
Splice isoforms : SwissVarQ96PM9
PhosPhoSitePlusQ96PM9
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_U1   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  ZnF_U1 (SM00451)  
Conserved Domain (NCBI)ZNF385A
DMDM Disease mutations25946
Blocks (Seattle)ZNF385A
SuperfamilyQ96PM9
Human Protein AtlasENSG00000161642
Peptide AtlasQ96PM9
HPRD16448
IPIIPI00163238   IPI01021276   IPI01021756   IPI01020990   IPI01021429   IPI01020671   IPI01022912   IPI01020813   IPI01022590   IPI00792993   IPI00334747   
Protein Interaction databases
DIP (DOE-UCLA)Q96PM9
IntAct (EBI)Q96PM9
FunCoupENSG00000161642
BioGRIDZNF385A
STRING (EMBL)ZNF385A
ZODIACZNF385A
Ontologies - Pathways
QuickGOQ96PM9
Ontology : AmiGOnuclear chromatin  p53 binding  DNA binding  RNA binding  mRNA 3'-UTR binding  mRNA 3'-UTR binding  nucleoplasm  nucleolus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  apoptotic process  cellular response to DNA damage stimulus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  hemostasis  learning or memory  locomotory behavior  zinc ion binding  mRNA localization resulting in posttranscriptional regulation of gene expression  mRNA localization resulting in posttranscriptional regulation of gene expression  platelet formation  dendrite  megakaryocyte development  neuronal cell body  neuronal cell body  positive regulation of fat cell differentiation  platelet alpha granule organization  regulation of signal transduction by p53 class mediator  positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator  negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  regulation of cytoplasmic translation  regulation of cytoplasmic translation  
Ontology : EGO-EBInuclear chromatin  p53 binding  DNA binding  RNA binding  mRNA 3'-UTR binding  mRNA 3'-UTR binding  nucleoplasm  nucleolus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  apoptotic process  cellular response to DNA damage stimulus  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  hemostasis  learning or memory  locomotory behavior  zinc ion binding  mRNA localization resulting in posttranscriptional regulation of gene expression  mRNA localization resulting in posttranscriptional regulation of gene expression  platelet formation  dendrite  megakaryocyte development  neuronal cell body  neuronal cell body  positive regulation of fat cell differentiation  platelet alpha granule organization  regulation of signal transduction by p53 class mediator  positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator  negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator  regulation of cytoplasmic translation  regulation of cytoplasmic translation  
NDEx NetworkZNF385A
Atlas of Cancer Signalling NetworkZNF385A
Wikipedia pathwaysZNF385A
Orthology - Evolution
OrthoDB25946
GeneTree (enSembl)ENSG00000161642
Phylogenetic Trees/Animal Genes : TreeFamZNF385A
HOVERGENQ96PM9
HOGENOMQ96PM9
Homologs : HomoloGeneZNF385A
Homology/Alignments : Family Browser (UCSC)ZNF385A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF385A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF385A
dbVarZNF385A
ClinVarZNF385A
1000_GenomesZNF385A 
Exome Variant ServerZNF385A
ExAC (Exome Aggregation Consortium)ZNF385A (select the gene name)
Genetic variants : HAPMAP25946
Genomic Variants (DGV)ZNF385A [DGVbeta]
DECIPHERZNF385A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF385A 
Mutations
ICGC Data PortalZNF385A 
TCGA Data PortalZNF385A 
Broad Tumor PortalZNF385A
OASIS PortalZNF385A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF385A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF385A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF385A
DgiDB (Drug Gene Interaction Database)ZNF385A
DoCM (Curated mutations)ZNF385A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF385A (select a term)
intoGenZNF385A
Cancer3DZNF385A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609124   
Orphanet
MedgenZNF385A
Genetic Testing Registry ZNF385A
NextProtQ96PM9 [Medical]
TSGene25946
GENETestsZNF385A
Target ValidationZNF385A
Huge Navigator ZNF385A [HugePedia]
snp3D : Map Gene to Disease25946
BioCentury BCIQZNF385A
ClinGenZNF385A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25946
Chemical/Pharm GKB GenePA162410095
Clinical trialZNF385A
Miscellaneous
canSAR (ICR)ZNF385A (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF385A
EVEXZNF385A
GoPubMedZNF385A
iHOPZNF385A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:44:41 CEST 2017

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