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ZNF395 (zinc finger protein 395)

Identity

Alias (NCBI)HDBP-2
HDBP2
HDRF-2
PBF
PRF-1
PRF1
Si-1-8-14
HGNC (Hugo) ZNF395
HGNC Alias symbPRF-1
HDBP2
PBF
DKFZp434K1210
LocusID (NCBI) 55893
Atlas_Id 50674
Location 8p21.1  [Link to chromosome band 8p21]
Location_base_pair Starts at 28345590 and ends at 28386460 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CDCA8 (1p34.3) / ZNF395 (8p21.1)RRP7A (22q13.2) / ZNF395 (8p21.1)ZNF395 (8p21.1) / SLC25A44 (1q22)
ZNF395 (8p21.1) / ZNF395 (8p21.1)ZNF395 8p21.1 / SLC25A44 1q22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)ZNF395   18737
Cards
Entrez_Gene (NCBI)ZNF395    zinc finger protein 395
AliasesHDBP-2; HDBP2; HDRF-2; PBF; 
PRF-1; PRF1; Si-1-8-14
GeneCards (Weizmann)ZNF395
Ensembl hg19 (Hinxton)ENSG00000186918 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186918 [Gene_View]  ENSG00000186918 [Sequence]  chr8:28345590-28386460 [Contig_View]  ZNF395 [Vega]
ICGC DataPortalENSG00000186918
TCGA cBioPortalZNF395
AceView (NCBI)ZNF395
Genatlas (Paris)ZNF395
SOURCE (Princeton)ZNF395
Genetics Home Reference (NIH)ZNF395
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF395  -     chr8:28345590-28386460 -  8p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF395  -     8p21.1   [Description]    (hg19-Feb_2009)
GoldenPathZNF395 - 8p21.1 [CytoView hg19]  ZNF395 - 8p21.1 [CytoView hg38]
ImmunoBaseENSG00000186918
Genome Data Viewer NCBIZNF395 [Mapview hg19]  
OMIM609494   
Gene and transcription
Genbank (Entrez)AB044750 AB044751 AB044752 AB057659 AB073627
RefSeq transcript (Entrez)NM_018660
Consensus coding sequences : CCDS (NCBI)ZNF395
Gene ExpressionZNF395 [ NCBI-GEO ]   ZNF395 [ EBI - ARRAY_EXPRESS ]   ZNF395 [ SEEK ]   ZNF395 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF395 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF395 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55893
GTEX Portal (Tissue expression)ZNF395
Human Protein AtlasENSG00000186918-ZNF395 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H8N7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H8N7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H8N7
PhosPhoSitePlusQ9H8N7
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)DUF4772    Znf_C2H2_type   
Domain families : Pfam (Sanger)DUF4772 (PF15997)   
Domain families : Pfam (NCBI)pfam15997   
Conserved Domain (NCBI)ZNF395
SuperfamilyQ9H8N7
AlphaFold pdb e-kbQ9H8N7   
Human Protein Atlas [tissue]ENSG00000186918-ZNF395 [tissue]
HPRD11711
Protein Interaction databases
DIP (DOE-UCLA)Q9H8N7
IntAct (EBI)Q9H8N7
BioGRIDZNF395
STRING (EMBL)ZNF395
ZODIACZNF395
Ontologies - Pathways
QuickGOQ9H8N7
Ontology : AmiGORNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  cis-regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  nuclear speck  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIRNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  cis-regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  DNA-binding transcription factor activity  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  nuclear speck  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF395
Atlas of Cancer Signalling NetworkZNF395
Wikipedia pathwaysZNF395
Orthology - Evolution
OrthoDB55893
GeneTree (enSembl)ENSG00000186918
Phylogenetic Trees/Animal Genes : TreeFamZNF395
Homologs : HomoloGeneZNF395
Homology/Alignments : Family Browser (UCSC)ZNF395
Gene fusions - Rearrangements
Fusion : MitelmanZNF395/SLC25A44 [8p21.1/1q22]  
Fusion : QuiverZNF395
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF395 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF395
dbVarZNF395
ClinVarZNF395
MonarchZNF395
1000_GenomesZNF395 
Exome Variant ServerZNF395
GNOMAD BrowserENSG00000186918
Varsome BrowserZNF395
ACMGZNF395 variants
VarityQ9H8N7
Genomic Variants (DGV)ZNF395 [DGVbeta]
DECIPHERZNF395 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF395 
Mutations
ICGC Data PortalZNF395 
TCGA Data PortalZNF395 
Broad Tumor PortalZNF395
OASIS PortalZNF395 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF395  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF395
Mutations and Diseases : HGMDZNF395
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF395
DgiDB (Drug Gene Interaction Database)ZNF395
DoCM (Curated mutations)ZNF395
CIViC (Clinical Interpretations of Variants in Cancer)ZNF395
Cancer3DZNF395
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609494   
Orphanet
DisGeNETZNF395
MedgenZNF395
Genetic Testing Registry ZNF395
NextProtQ9H8N7 [Medical]
GENETestsZNF395
Target ValidationZNF395
Huge Navigator ZNF395 [HugePedia]
ClinGenZNF395
Clinical trials, drugs, therapy
MyCancerGenomeZNF395
Protein Interactions : CTDZNF395
Pharm GKB GenePA134978145
PharosQ9H8N7
Clinical trialZNF395
Miscellaneous
canSAR (ICR)ZNF395
HarmonizomeZNF395
DataMed IndexZNF395
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF395
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:39:16 CEST 2021
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