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ZNF408 (zinc finger protein 408)

Identity

Alias_symbol (synonym)FLJ12827
Other aliasEVR6
RP72
HGNC (Hugo) ZNF408
LocusID (NCBI) 79797
Atlas_Id 76138
Location 11p11.2  [Link to chromosome band 11p11]
Location_base_pair Starts at 46701094 and ends at 46705916 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DDB1 (11q12.2) / ZNF408 (11p11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ZNF408   20041
Cards
Entrez_Gene (NCBI)ZNF408  79797  zinc finger protein 408
AliasesEVR6; RP72
GeneCards (Weizmann)ZNF408
Ensembl hg19 (Hinxton)ENSG00000175213 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175213 [Gene_View]  ENSG00000175213 [Sequence]  chr11:46701094-46705916 [Contig_View]  ZNF408 [Vega]
ICGC DataPortalENSG00000175213
TCGA cBioPortalZNF408
AceView (NCBI)ZNF408
Genatlas (Paris)ZNF408
WikiGenes79797
SOURCE (Princeton)ZNF408
Genetics Home Reference (NIH)ZNF408
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF408  -     chr11:46701094-46705916 +  11p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF408  -     11p11.2   [Description]    (hg19-Feb_2009)
EnsemblZNF408 - 11p11.2 [CytoView hg19]  ZNF408 - 11p11.2 [CytoView hg38]
Mapping of homologs : NCBIZNF408 [Mapview hg19]  ZNF408 [Mapview hg38]
OMIM616454   616468   616469   
Gene and transcription
Genbank (Entrez)AF346626 AK022889 AK302180 AW246726 BC013355
RefSeq transcript (Entrez)NM_001184751 NM_024741
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF408
Cluster EST : UnigeneHs.656931 [ NCBI ]
CGAP (NCI)Hs.656931
Alternative Splicing GalleryENSG00000175213
Gene ExpressionZNF408 [ NCBI-GEO ]   ZNF408 [ EBI - ARRAY_EXPRESS ]   ZNF408 [ SEEK ]   ZNF408 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF408 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79797
GTEX Portal (Tissue expression)ZNF408
Human Protein AtlasENSG00000175213-ZNF408 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H9D4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H9D4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H9D4
Splice isoforms : SwissVarQ9H9D4
PhosPhoSitePlusQ9H9D4
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam13912   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF408
DMDM Disease mutations79797
Blocks (Seattle)ZNF408
SuperfamilyQ9H9D4
Human Protein Atlas [tissue]ENSG00000175213-ZNF408 [tissue]
Peptide AtlasQ9H9D4
HPRD18338
IPIIPI00015481   IPI00978290   
Protein Interaction databases
DIP (DOE-UCLA)Q9H9D4
IntAct (EBI)Q9H9D4
FunCoupENSG00000175213
BioGRIDZNF408
STRING (EMBL)ZNF408
ZODIACZNF408
Ontologies - Pathways
QuickGOQ9H9D4
Ontology : AmiGODNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  identical protein binding  metal ion binding  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  identical protein binding  metal ion binding  
NDEx NetworkZNF408
Atlas of Cancer Signalling NetworkZNF408
Wikipedia pathwaysZNF408
Orthology - Evolution
OrthoDB79797
GeneTree (enSembl)ENSG00000175213
Phylogenetic Trees/Animal Genes : TreeFamZNF408
HOVERGENQ9H9D4
HOGENOMQ9H9D4
Homologs : HomoloGeneZNF408
Homology/Alignments : Family Browser (UCSC)ZNF408
Gene fusions - Rearrangements
Fusion : QuiverZNF408
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF408 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF408
dbVarZNF408
ClinVarZNF408
1000_GenomesZNF408 
Exome Variant ServerZNF408
ExAC (Exome Aggregation Consortium)ENSG00000175213
GNOMAD BrowserENSG00000175213
Varsome BrowserZNF408
Genetic variants : HAPMAP79797
Genomic Variants (DGV)ZNF408 [DGVbeta]
DECIPHERZNF408 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF408 
Mutations
ICGC Data PortalZNF408 
TCGA Data PortalZNF408 
Broad Tumor PortalZNF408
OASIS PortalZNF408 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF408  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF408
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch ZNF408
DgiDB (Drug Gene Interaction Database)ZNF408
DoCM (Curated mutations)ZNF408 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF408 (select a term)
intoGenZNF408
Cancer3DZNF408(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616454    616468    616469   
Orphanet659    7036   
DisGeNETZNF408
MedgenZNF408
Genetic Testing Registry ZNF408
NextProtQ9H9D4 [Medical]
TSGene79797
GENETestsZNF408
Target ValidationZNF408
Huge Navigator ZNF408 [HugePedia]
snp3D : Map Gene to Disease79797
BioCentury BCIQZNF408
ClinGenZNF408
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79797
Chemical/Pharm GKB GenePA134936136
Clinical trialZNF408
Miscellaneous
canSAR (ICR)ZNF408 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF408
EVEXZNF408
GoPubMedZNF408
iHOPZNF408
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:39:44 CEST 2018
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