Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ZNF423 (zinc finger protein 423)

Identity

Alias_symbol (synonym)KIAA0760
OAZ
Roaz
Ebfaz
Zfp104
NPHP14
JBTS19
Other aliasZFP423
hOAZ
HGNC (Hugo) ZNF423
LocusID (NCBI) 23090
Atlas_Id 53614
Location 16q12.1  [Link to chromosome band 16q12]
Location_base_pair Starts at 49487531 and ends at 49857919 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ITFG1 (16q12.1) / ZNF423 (16q12.1)JARID2 (6p22.3) / ZNF423 (16q12.1)TM9SF4 (20q11.21) / ZNF423 (16q12.1)
UBR5 (8q22.3) / ZNF423 (16q12.1)ZNF423 (16q12.1) / ZNF423 (16q12.1)TM9SF4 20q11.21 / ZNF423 16q12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF423   16762
Cards
Entrez_Gene (NCBI)ZNF423  23090  zinc finger protein 423
AliasesEbfaz; JBTS19; NPHP14; OAZ; 
Roaz; ZFP423; Zfp104; hOAZ
GeneCards (Weizmann)ZNF423
Ensembl hg19 (Hinxton)ENSG00000102935 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102935 [Gene_View]  chr16:49487531-49857919 [Contig_View]  ZNF423 [Vega]
ICGC DataPortalENSG00000102935
TCGA cBioPortalZNF423
AceView (NCBI)ZNF423
Genatlas (Paris)ZNF423
WikiGenes23090
SOURCE (Princeton)ZNF423
Genetics Home Reference (NIH)ZNF423
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF423  -     chr16:49487531-49857919 -  16q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF423  -     16q12.1   [Description]    (hg19-Feb_2009)
EnsemblZNF423 - 16q12.1 [CytoView hg19]  ZNF423 - 16q12.1 [CytoView hg38]
Mapping of homologs : NCBIZNF423 [Mapview hg19]  ZNF423 [Mapview hg38]
OMIM604557   614844   
Gene and transcription
Genbank (Entrez)AB018303 AF221712 AK027479 AK304829 AK309835
RefSeq transcript (Entrez)NM_001271620 NM_001330533 NM_015069
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF423
Cluster EST : UnigeneHs.744482 [ NCBI ]
CGAP (NCI)Hs.744482
Alternative Splicing GalleryENSG00000102935
Gene ExpressionZNF423 [ NCBI-GEO ]   ZNF423 [ EBI - ARRAY_EXPRESS ]   ZNF423 [ SEEK ]   ZNF423 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF423 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23090
GTEX Portal (Tissue expression)ZNF423
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2M1K9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2M1K9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2M1K9
Splice isoforms : SwissVarQ2M1K9
PhosPhoSitePlusQ2M1K9
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam13912   
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF423
DMDM Disease mutations23090
Blocks (Seattle)ZNF423
PDB (SRS)2MDG   
PDB (PDBSum)2MDG   
PDB (IMB)2MDG   
PDB (RSDB)2MDG   
Structural Biology KnowledgeBase2MDG   
SCOP (Structural Classification of Proteins)2MDG   
CATH (Classification of proteins structures)2MDG   
SuperfamilyQ2M1K9
Human Protein AtlasENSG00000102935
Peptide AtlasQ2M1K9
HPRD05189
IPIIPI00100660   IPI01014875   
Protein Interaction databases
DIP (DOE-UCLA)Q2M1K9
IntAct (EBI)Q2M1K9
FunCoupENSG00000102935
BioGRIDZNF423
STRING (EMBL)ZNF423
ZODIACZNF423
Ontologies - Pathways
QuickGOQ2M1K9
Ontology : AmiGODNA binding  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  Notch signaling pathway  nervous system development  cell differentiation  positive regulation of BMP signaling pathway  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  nucleoplasm  transcription, DNA-templated  Notch signaling pathway  nervous system development  cell differentiation  positive regulation of BMP signaling pathway  negative regulation of transcription, DNA-templated  positive regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF423
Atlas of Cancer Signalling NetworkZNF423
Wikipedia pathwaysZNF423
Orthology - Evolution
OrthoDB23090
GeneTree (enSembl)ENSG00000102935
Phylogenetic Trees/Animal Genes : TreeFamZNF423
HOVERGENQ2M1K9
HOGENOMQ2M1K9
Homologs : HomoloGeneZNF423
Homology/Alignments : Family Browser (UCSC)ZNF423
Gene fusions - Rearrangements
Fusion : MitelmanTM9SF4/ZNF423 [20q11.21/16q12.1]  [t(16;20)(q12;q11)]  
Fusion : MitelmanUBR5/ZNF423 [8q22.3/16q12.1]  [t(8;16)(q22;q12)]  
Fusion: TCGATM9SF4 20q11.21 ZNF423 16q12.1 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF423 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF423
dbVarZNF423
ClinVarZNF423
1000_GenomesZNF423 
Exome Variant ServerZNF423
ExAC (Exome Aggregation Consortium)ZNF423 (select the gene name)
Genetic variants : HAPMAP23090
Genomic Variants (DGV)ZNF423 [DGVbeta]
DECIPHERZNF423 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF423 
Mutations
ICGC Data PortalZNF423 
TCGA Data PortalZNF423 
Broad Tumor PortalZNF423
OASIS PortalZNF423 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF423  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF423
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Eye diseases - LOVD
BioMutasearch ZNF423
DgiDB (Drug Gene Interaction Database)ZNF423
DoCM (Curated mutations)ZNF423 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF423 (select a term)
intoGenZNF423
Cancer3DZNF423(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604557    614844   
Orphanet519   
MedgenZNF423
Genetic Testing Registry ZNF423
NextProtQ2M1K9 [Medical]
TSGene23090
GENETestsZNF423
Target ValidationZNF423
Huge Navigator ZNF423 [HugePedia]
snp3D : Map Gene to Disease23090
BioCentury BCIQZNF423
ClinGenZNF423
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23090
Chemical/Pharm GKB GenePA134903681
Clinical trialZNF423
Miscellaneous
canSAR (ICR)ZNF423 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF423
EVEXZNF423
GoPubMedZNF423
iHOPZNF423
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:48 CEST 2017

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