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ZNF43 (zinc finger protein 43)

Identity

Alias (NCBI)HTF6
KOX27
ZNF39L1
HGNC (Hugo) ZNF43
HGNC Alias symbHTF6
KOX27
HGNC Previous nameZNF39L1
HGNC Previous namezinc finger protein 39-like 1 (KOX 27)
 zinc finger protein 43 (HTF6)
LocusID (NCBI) 7594
Atlas_Id 42882
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 21804946 and ends at 21836182 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COL3A1 (2q32.2)::ZNF43 (19p12)ZNF43 (19p12)::CKAP5 (11p11.2)ZNF43 (19p12)::EFHB (3p24.3)
ZNF43 19p12::EFHB 3p24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF43   13109
Cards
Entrez_Gene (NCBI)ZNF43    zinc finger protein 43
AliasesHTF6; KOX27; ZNF39L1
GeneCards (Weizmann)ZNF43
Ensembl hg19 (Hinxton)ENSG00000198521 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198521 [Gene_View]  ENSG00000198521 [Sequence]  chr19:21804946-21836182 [Contig_View]  ZNF43 [Vega]
ICGC DataPortalENSG00000198521
TCGA cBioPortalZNF43
AceView (NCBI)ZNF43
Genatlas (Paris)ZNF43
SOURCE (Princeton)ZNF43
Genetics Home Reference (NIH)ZNF43
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF43  -     chr19:21804946-21836182 -  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF43  -     19p12   [Description]    (hg19-Feb_2009)
GoldenPathZNF43 - 19p12 [CytoView hg19]  ZNF43 - 19p12 [CytoView hg38]
ImmunoBaseENSG00000198521
Genome Data Viewer NCBIZNF43 [Mapview hg19]  
OMIM603972   
Gene and transcription
Genbank (Entrez)AF112859 AK022905 AK291353 BC006528 BT009756
RefSeq transcript (Entrez)NM_001256648 NM_001256649 NM_001256650 NM_001256651 NM_001256653 NM_001256654 NM_003423
Consensus coding sequences : CCDS (NCBI)ZNF43
Gene ExpressionZNF43 [ NCBI-GEO ]   ZNF43 [ EBI - ARRAY_EXPRESS ]   ZNF43 [ SEEK ]   ZNF43 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF43 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF43 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7594
GTEX Portal (Tissue expression)ZNF43
Human Protein AtlasENSG00000198521-ZNF43 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17038   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17038  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17038
PhosPhoSitePlusP17038
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF43
SuperfamilyP17038
AlphaFold pdb e-kbP17038   
Human Protein Atlas [tissue]ENSG00000198521-ZNF43 [tissue]
HPRD04917
Protein Interaction databases
DIP (DOE-UCLA)P17038
IntAct (EBI)P17038
BioGRIDZNF43
STRING (EMBL)ZNF43
ZODIACZNF43
Ontologies - Pathways
QuickGOP17038
Ontology : AmiGORNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIRNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of transcription by RNA polymerase II  positive regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF43
Atlas of Cancer Signalling NetworkZNF43
Wikipedia pathwaysZNF43
Orthology - Evolution
OrthoDB7594
GeneTree (enSembl)ENSG00000198521
Phylogenetic Trees/Animal Genes : TreeFamZNF43
Homologs : HomoloGeneZNF43
Homology/Alignments : Family Browser (UCSC)ZNF43
Gene fusions - Rearrangements
Fusion : MitelmanCOL3A1::ZNF43 [2q32.2/19p12]  
Fusion : MitelmanZNF43::EFHB [19p12/3p24.3]  
Fusion : QuiverZNF43
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF43 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF43
dbVarZNF43
ClinVarZNF43
MonarchZNF43
1000_GenomesZNF43 
Exome Variant ServerZNF43
GNOMAD BrowserENSG00000198521
Varsome BrowserZNF43
ACMGZNF43 variants
VarityP17038
Genomic Variants (DGV)ZNF43 [DGVbeta]
DECIPHERZNF43 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF43 
Mutations
ICGC Data PortalZNF43 
TCGA Data PortalZNF43 
Broad Tumor PortalZNF43
OASIS PortalZNF43 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF43  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF43
Mutations and Diseases : HGMDZNF43
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF43
DgiDB (Drug Gene Interaction Database)ZNF43
DoCM (Curated mutations)ZNF43
CIViC (Clinical Interpretations of Variants in Cancer)ZNF43
Cancer3DZNF43
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603972   
Orphanet
DisGeNETZNF43
MedgenZNF43
Genetic Testing Registry ZNF43
NextProtP17038 [Medical]
GENETestsZNF43
Target ValidationZNF43
Huge Navigator ZNF43 [HugePedia]
ClinGenZNF43
Clinical trials, drugs, therapy
MyCancerGenomeZNF43
Protein Interactions : CTDZNF43
Pharm GKB GenePA37684
PharosP17038
Clinical trialZNF43
Miscellaneous
canSAR (ICR)ZNF43
HarmonizomeZNF43
ARCHS4ZNF43
DataMed IndexZNF43
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF43
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 13:07:38 CET 2022

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