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ZNF43 (zinc finger protein 43)

Identity

Alias_namesZNF39L1
zinc finger protein 39-like 1 (KOX 27)
zinc finger protein 43 (HTF6)
Alias_symbol (synonym)HTF6
KOX27
Other alias
HGNC (Hugo) ZNF43
LocusID (NCBI) 7594
Atlas_Id 42882
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 21804949 and ends at 21836208 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
COL3A1 (2q32.2) / ZNF43 (19p12)ZNF43 (19p12) / CKAP5 (11p11.2)ZNF43 (19p12) / EFHB (3p24.3)
ZNF43 19p12 / EFHB 3p24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]

Solid Tumors TT_t0219q32p12ID105097 TT_t0319p24p12ID105693


External links

Nomenclature
HGNC (Hugo)ZNF43   13109
Cards
Entrez_Gene (NCBI)ZNF43  7594  zinc finger protein 43
AliasesHTF6; KOX27; ZNF39L1
GeneCards (Weizmann)ZNF43
Ensembl hg19 (Hinxton)ENSG00000198521 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198521 [Gene_View]  ENSG00000198521 [Sequence]  chr19:21804949-21836208 [Contig_View]  ZNF43 [Vega]
ICGC DataPortalENSG00000198521
TCGA cBioPortalZNF43
AceView (NCBI)ZNF43
Genatlas (Paris)ZNF43
WikiGenes7594
SOURCE (Princeton)ZNF43
Genetics Home Reference (NIH)ZNF43
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF43  -     chr19:21804949-21836208 -  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF43  -     19p12   [Description]    (hg19-Feb_2009)
GoldenPathZNF43 - 19p12 [CytoView hg19]  ZNF43 - 19p12 [CytoView hg38]
ImmunoBaseENSG00000198521
Mapping of homologs : NCBIZNF43 [Mapview hg19]  ZNF43 [Mapview hg38]
OMIM603972   
Gene and transcription
Genbank (Entrez)AF112859 AK022905 AK291353 BC006528 BT009756
RefSeq transcript (Entrez)NM_001256648 NM_001256649 NM_001256650 NM_001256651 NM_001256653 NM_001256654 NM_003423
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF43
Cluster EST : UnigeneHs.534365 [ NCBI ]
CGAP (NCI)Hs.534365
Alternative Splicing GalleryENSG00000198521
Gene ExpressionZNF43 [ NCBI-GEO ]   ZNF43 [ EBI - ARRAY_EXPRESS ]   ZNF43 [ SEEK ]   ZNF43 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF43 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7594
GTEX Portal (Tissue expression)ZNF43
Human Protein AtlasENSG00000198521-ZNF43 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17038   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17038  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17038
Splice isoforms : SwissVarP17038
PhosPhoSitePlusP17038
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)   
Domain families : Pfam (NCBI)pfam01352   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF43
DMDM Disease mutations7594
Blocks (Seattle)ZNF43
SuperfamilyP17038
Human Protein Atlas [tissue]ENSG00000198521-ZNF43 [tissue]
Peptide AtlasP17038
HPRD04917
IPIIPI00787541   IPI00012395   
Protein Interaction databases
DIP (DOE-UCLA)P17038
IntAct (EBI)P17038
FunCoupENSG00000198521
BioGRIDZNF43
STRING (EMBL)ZNF43
ZODIACZNF43
Ontologies - Pathways
QuickGOP17038
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF43
Atlas of Cancer Signalling NetworkZNF43
Wikipedia pathwaysZNF43
Orthology - Evolution
OrthoDB7594
GeneTree (enSembl)ENSG00000198521
Phylogenetic Trees/Animal Genes : TreeFamZNF43
HOGENOMP17038
Homologs : HomoloGeneZNF43
Homology/Alignments : Family Browser (UCSC)ZNF43
Gene fusions - Rearrangements
Fusion : MitelmanCOL3A1/ZNF43 [2q32.2/19p12]  [t(2;19)(q32;p12)]  
Fusion : MitelmanZNF43/EFHB [19p12/3p24.3]  [t(3;19)(p24;p12)]  
Fusion PortalZNF43 19p12 EFHB 3p24.3 PRAD
Fusion : QuiverZNF43
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF43 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF43
dbVarZNF43
ClinVarZNF43
1000_GenomesZNF43 
Exome Variant ServerZNF43
ExAC (Exome Aggregation Consortium)ENSG00000198521
GNOMAD BrowserENSG00000198521
Varsome BrowserZNF43
Genetic variants : HAPMAP7594
Genomic Variants (DGV)ZNF43 [DGVbeta]
DECIPHERZNF43 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF43 
Mutations
ICGC Data PortalZNF43 
TCGA Data PortalZNF43 
Broad Tumor PortalZNF43
OASIS PortalZNF43 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF43  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF43
Mutations and Diseases : HGMDZNF43
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF43
DgiDB (Drug Gene Interaction Database)ZNF43
DoCM (Curated mutations)ZNF43 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF43 (select a term)
intoGenZNF43
Cancer3DZNF43(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603972   
Orphanet
DisGeNETZNF43
MedgenZNF43
Genetic Testing Registry ZNF43
NextProtP17038 [Medical]
TSGene7594
GENETestsZNF43
Target ValidationZNF43
Huge Navigator ZNF43 [HugePedia]
snp3D : Map Gene to Disease7594
BioCentury BCIQZNF43
ClinGenZNF43
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7594
Chemical/Pharm GKB GenePA37684
Clinical trialZNF43
Miscellaneous
canSAR (ICR)ZNF43 (select the gene name)
DataMed IndexZNF43
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF43
EVEXZNF43
GoPubMedZNF43
iHOPZNF43
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 26 18:36:13 CEST 2019

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