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ZNF486 (zinc finger protein 486)

Identity

Alias_namesKRBO2
KRAB domain only 2
Alias_symbol (synonym)MGC2396
Other alias
HGNC (Hugo) ZNF486
LocusID (NCBI) 90649
Atlas_Id 76182
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 20167214 and ends at 20200490 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF486   20807
Cards
Entrez_Gene (NCBI)ZNF486  90649  zinc finger protein 486
AliasesKRBO2
GeneCards (Weizmann)ZNF486
Ensembl hg19 (Hinxton)ENSG00000256229 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000256229 [Gene_View]  chr19:20167214-20200490 [Contig_View]  ZNF486 [Vega]
ICGC DataPortalENSG00000256229
TCGA cBioPortalZNF486
AceView (NCBI)ZNF486
Genatlas (Paris)ZNF486
WikiGenes90649
SOURCE (Princeton)ZNF486
Genetics Home Reference (NIH)ZNF486
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF486  -     chr19:20167214-20200490 +  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF486  -     19p12   [Description]    (hg19-Feb_2009)
EnsemblZNF486 - 19p12 [CytoView hg19]  ZNF486 - 19p12 [CytoView hg38]
Mapping of homologs : NCBIZNF486 [Mapview hg19]  ZNF486 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB209550 BC008936 BC027608 BC117268
RefSeq transcript (Entrez)NM_052852
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF486
Cluster EST : UnigeneHs.590991 [ NCBI ]
CGAP (NCI)Hs.590991
Alternative Splicing GalleryENSG00000256229
Gene ExpressionZNF486 [ NCBI-GEO ]   ZNF486 [ EBI - ARRAY_EXPRESS ]   ZNF486 [ SEEK ]   ZNF486 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF486 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90649
GTEX Portal (Tissue expression)ZNF486
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96H40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96H40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96H40
Splice isoforms : SwissVarQ96H40
PhosPhoSitePlusQ96H40
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam01352    pfam00096    pfam13912   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF486
DMDM Disease mutations90649
Blocks (Seattle)ZNF486
SuperfamilyQ96H40
Human Protein AtlasENSG00000256229
Peptide AtlasQ96H40
IPIIPI00397702   IPI01010412   
Protein Interaction databases
DIP (DOE-UCLA)Q96H40
IntAct (EBI)Q96H40
FunCoupENSG00000256229
BioGRIDZNF486
STRING (EMBL)ZNF486
ZODIACZNF486
Ontologies - Pathways
QuickGOQ96H40
Ontology : AmiGOmolecular_function  DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  biological_process  metal ion binding  extracellular exosome  
Ontology : EGO-EBImolecular_function  DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  biological_process  metal ion binding  extracellular exosome  
NDEx NetworkZNF486
Atlas of Cancer Signalling NetworkZNF486
Wikipedia pathwaysZNF486
Orthology - Evolution
OrthoDB90649
GeneTree (enSembl)ENSG00000256229
Phylogenetic Trees/Animal Genes : TreeFamZNF486
HOVERGENQ96H40
HOGENOMQ96H40
Homologs : HomoloGeneZNF486
Homology/Alignments : Family Browser (UCSC)ZNF486
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF486 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF486
dbVarZNF486
ClinVarZNF486
1000_GenomesZNF486 
Exome Variant ServerZNF486
ExAC (Exome Aggregation Consortium)ZNF486 (select the gene name)
Genetic variants : HAPMAP90649
Genomic Variants (DGV)ZNF486 [DGVbeta]
DECIPHERZNF486 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF486 
Mutations
ICGC Data PortalZNF486 
TCGA Data PortalZNF486 
Broad Tumor PortalZNF486
OASIS PortalZNF486 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF486  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF486
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF486
DgiDB (Drug Gene Interaction Database)ZNF486
DoCM (Curated mutations)ZNF486 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF486 (select a term)
intoGenZNF486
Cancer3DZNF486(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF486
Genetic Testing Registry ZNF486
NextProtQ96H40 [Medical]
TSGene90649
GENETestsZNF486
Target ValidationZNF486
Huge Navigator ZNF486 [HugePedia]
snp3D : Map Gene to Disease90649
BioCentury BCIQZNF486
ClinGenZNF486
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90649
Chemical/Pharm GKB GenePA134919932
Clinical trialZNF486
Miscellaneous
canSAR (ICR)ZNF486 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF486
EVEXZNF486
GoPubMedZNF486
iHOPZNF486
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:50:32 CEST 2017

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