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ZNF486 (zinc finger protein 486)

Identity

Alias (NCBI)KRBO2
HGNC (Hugo) ZNF486
HGNC Alias symbMGC2396
HGNC Previous nameKRBO2
HGNC Previous nameKRAB domain only 2
LocusID (NCBI) 90649
Atlas_Id 76182
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 20167214 and ends at 20200488 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF486   20807
Cards
Entrez_Gene (NCBI)ZNF486    zinc finger protein 486
AliasesKRBO2
GeneCards (Weizmann)ZNF486
Ensembl hg19 (Hinxton)ENSG00000256229 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000256229 [Gene_View]  ENSG00000256229 [Sequence]  chr19:20167214-20200488 [Contig_View]  ZNF486 [Vega]
ICGC DataPortalENSG00000256229
TCGA cBioPortalZNF486
AceView (NCBI)ZNF486
Genatlas (Paris)ZNF486
SOURCE (Princeton)ZNF486
Genetics Home Reference (NIH)ZNF486
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF486  -     chr19:20167214-20200488 +  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF486  -     19p12   [Description]    (hg19-Feb_2009)
GoldenPathZNF486 - 19p12 [CytoView hg19]  ZNF486 - 19p12 [CytoView hg38]
ImmunoBaseENSG00000256229
Genome Data Viewer NCBIZNF486 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB209550 BC008936 BC027608 BC117268
RefSeq transcript (Entrez)NM_052852
Consensus coding sequences : CCDS (NCBI)ZNF486
Gene ExpressionZNF486 [ NCBI-GEO ]   ZNF486 [ EBI - ARRAY_EXPRESS ]   ZNF486 [ SEEK ]   ZNF486 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF486 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF486 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90649
GTEX Portal (Tissue expression)ZNF486
Human Protein AtlasENSG00000256229-ZNF486 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96H40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96H40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96H40
PhosPhoSitePlusQ96H40
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF486
SuperfamilyQ96H40
AlphaFold pdb e-kbQ96H40   
Human Protein Atlas [tissue]ENSG00000256229-ZNF486 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q96H40
IntAct (EBI)Q96H40
BioGRIDZNF486
STRING (EMBL)ZNF486
ZODIACZNF486
Ontologies - Pathways
QuickGOQ96H40
Ontology : AmiGORNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  molecular_function  nucleus  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  biological_process  metal ion binding  extracellular exosome  
Ontology : EGO-EBIRNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  molecular_function  nucleus  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  biological_process  metal ion binding  extracellular exosome  
NDEx NetworkZNF486
Atlas of Cancer Signalling NetworkZNF486
Wikipedia pathwaysZNF486
Orthology - Evolution
OrthoDB90649
GeneTree (enSembl)ENSG00000256229
Phylogenetic Trees/Animal Genes : TreeFamZNF486
Homologs : HomoloGeneZNF486
Homology/Alignments : Family Browser (UCSC)ZNF486
Gene fusions - Rearrangements
Fusion : QuiverZNF486
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF486 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF486
dbVarZNF486
ClinVarZNF486
MonarchZNF486
1000_GenomesZNF486 
Exome Variant ServerZNF486
GNOMAD BrowserENSG00000256229
Varsome BrowserZNF486
ACMGZNF486 variants
VarityQ96H40
Genomic Variants (DGV)ZNF486 [DGVbeta]
DECIPHERZNF486 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF486 
Mutations
ICGC Data PortalZNF486 
TCGA Data PortalZNF486 
Broad Tumor PortalZNF486
OASIS PortalZNF486 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF486  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF486
Mutations and Diseases : HGMDZNF486
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF486
DgiDB (Drug Gene Interaction Database)ZNF486
DoCM (Curated mutations)ZNF486
CIViC (Clinical Interpretations of Variants in Cancer)ZNF486
Cancer3DZNF486
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF486
MedgenZNF486
Genetic Testing Registry ZNF486
NextProtQ96H40 [Medical]
GENETestsZNF486
Target ValidationZNF486
Huge Navigator ZNF486 [HugePedia]
ClinGenZNF486
Clinical trials, drugs, therapy
MyCancerGenomeZNF486
Protein Interactions : CTDZNF486
Pharm GKB GenePA134919932
PharosQ96H40
Clinical trialZNF486
Miscellaneous
canSAR (ICR)ZNF486
HarmonizomeZNF486
ARCHS4ZNF486
DataMed IndexZNF486
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF486
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 13:59:50 CET 2022

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