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ZNF487 (zinc finger protein 487)

Identity

Alias_namesKRBO1
ZNF487P
KRAB domain only 1
zinc finger protein 487, pseudogene
Other alias
HGNC (Hugo) ZNF487
LocusID (NCBI) 642819
Atlas_Id 76183
Location 10q11.21  [Link to chromosome band 10q11]
Location_base_pair Starts at 43437111 and ends at 43483181 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZNF487 (10q11.21) / FXYD4 (10q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  ZNF487/FXYD4 (10q11)

External links

Nomenclature
HGNC (Hugo)ZNF487   23488
Cards
Entrez_Gene (NCBI)ZNF487  642819  zinc finger protein 487
AliasesKRBO1; ZNF487P
GeneCards (Weizmann)ZNF487
Ensembl hg19 (Hinxton)ENSG00000243660 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000243660 [Gene_View]  ENSG00000243660 [Sequence]  chr10:43437111-43483181 [Contig_View]  ZNF487 [Vega]
ICGC DataPortalENSG00000243660
TCGA cBioPortalZNF487
AceView (NCBI)ZNF487
Genatlas (Paris)ZNF487
WikiGenes642819
SOURCE (Princeton)ZNF487
Genetics Home Reference (NIH)ZNF487
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF487  -     chr10:43437111-43483181 +  10q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF487  -     10q11.21   [Description]    (hg19-Feb_2009)
GoldenPathZNF487 - 10q11.21 [CytoView hg19]  ZNF487 - 10q11.21 [CytoView hg38]
ImmunoBaseENSG00000243660
Mapping of homologs : NCBIZNF487 [Mapview hg19]  ZNF487 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK302442
RefSeq transcript (Entrez)NM_001355444 NM_001355445 NM_001355446 NM_001355447 NM_001355448 NM_001355449 NM_001355450
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF487
Alternative Splicing GalleryENSG00000243660
Gene ExpressionZNF487 [ NCBI-GEO ]   ZNF487 [ EBI - ARRAY_EXPRESS ]   ZNF487 [ SEEK ]   ZNF487 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF487 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)642819
GTEX Portal (Tissue expression)ZNF487
Human Protein AtlasENSG00000243660-ZNF487 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtB1APH4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtB1APH4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProB1APH4
Splice isoforms : SwissVarB1APH4
PhosPhoSitePlusB1APH4
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF487
DMDM Disease mutations642819
Blocks (Seattle)ZNF487
SuperfamilyB1APH4
Human Protein Atlas [tissue]ENSG00000243660-ZNF487 [tissue]
Peptide AtlasB1APH4
IPIIPI00888187   IPI00878370   IPI00896506   IPI00916109   IPI00915812   
Protein Interaction databases
DIP (DOE-UCLA)B1APH4
IntAct (EBI)B1APH4
FunCoupENSG00000243660
BioGRIDZNF487
STRING (EMBL)ZNF487
ZODIACZNF487
Ontologies - Pathways
QuickGOB1APH4
Ontology : AmiGOnuclear chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  sequence-specific DNA binding  metal ion binding  
Ontology : EGO-EBInuclear chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity  nucleus  regulation of transcription by RNA polymerase II  sequence-specific DNA binding  metal ion binding  
NDEx NetworkZNF487
Atlas of Cancer Signalling NetworkZNF487
Wikipedia pathwaysZNF487
Orthology - Evolution
OrthoDB642819
GeneTree (enSembl)ENSG00000243660
Phylogenetic Trees/Animal Genes : TreeFamZNF487
HOGENOMB1APH4
Homologs : HomoloGeneZNF487
Homology/Alignments : Family Browser (UCSC)ZNF487
Gene fusions - Rearrangements
Fusion : QuiverZNF487
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF487 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF487
dbVarZNF487
ClinVarZNF487
1000_GenomesZNF487 
Exome Variant ServerZNF487
ExAC (Exome Aggregation Consortium)ENSG00000243660
GNOMAD BrowserENSG00000243660
Varsome BrowserZNF487
Genetic variants : HAPMAP642819
Genomic Variants (DGV)ZNF487 [DGVbeta]
DECIPHERZNF487 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF487 
Mutations
ICGC Data PortalZNF487 
TCGA Data PortalZNF487 
Broad Tumor PortalZNF487
OASIS PortalZNF487 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF487  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF487
Mutations and Diseases : HGMDZNF487
BioMutasearch ZNF487
DgiDB (Drug Gene Interaction Database)ZNF487
DoCM (Curated mutations)ZNF487 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF487 (select a term)
intoGenZNF487
Cancer3DZNF487(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF487
MedgenZNF487
Genetic Testing Registry ZNF487
NextProtB1APH4 [Medical]
TSGene642819
GENETestsZNF487
Target ValidationZNF487
Huge Navigator ZNF487 [HugePedia]
snp3D : Map Gene to Disease642819
BioCentury BCIQZNF487
ClinGenZNF487
Clinical trials, drugs, therapy
Protein Interactions : CTD642819
Pharm GKB GenePA143485525
Clinical trialZNF487
Miscellaneous
canSAR (ICR)ZNF487 (select the gene name)
HarmonizomeZNF487
DataMed IndexZNF487
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF487
EVEXZNF487
GoPubMedZNF487
iHOPZNF487
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Jun 30 20:07:26 CEST 2020
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