Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ZNF490 (zinc finger protein 490)

Identity

Alias (NCBI)-
HGNC (Hugo) ZNF490
HGNC Alias symbKIAA1198
LocusID (NCBI) 57474
Atlas_Id 54806
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 12576101 and ends at 12610813 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ITSN1 (21q22.11) / ZNF490 (19p13.2)ZNF490 (19p13.2) / ITSN1 (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(19;21)(p13;q22) ZNF490/ITSN1
t(19;21)(p13;q22) ITSN1/ZNF490

External links

Nomenclature
HGNC (Hugo)ZNF490   23705
Cards
Entrez_Gene (NCBI)ZNF490    zinc finger protein 490
Aliases
GeneCards (Weizmann)ZNF490
Ensembl hg19 (Hinxton)ENSG00000188033 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188033 [Gene_View]  ENSG00000188033 [Sequence]  chr19:12576101-12610813 [Contig_View]  ZNF490 [Vega]
ICGC DataPortalENSG00000188033
TCGA cBioPortalZNF490
AceView (NCBI)ZNF490
Genatlas (Paris)ZNF490
SOURCE (Princeton)ZNF490
Genetics Home Reference (NIH)ZNF490
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF490  -     chr19:12576101-12610813 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF490  -     19p13.2   [Description]    (hg19-Feb_2009)
GoldenPathZNF490 - 19p13.2 [CytoView hg19]  ZNF490 - 19p13.2 [CytoView hg38]
ImmunoBaseENSG00000188033
genome Data Viewer NCBIZNF490 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB033024 BC038586
RefSeq transcript (Entrez)NM_020714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF490
Alternative Splicing GalleryENSG00000188033
Gene ExpressionZNF490 [ NCBI-GEO ]   ZNF490 [ EBI - ARRAY_EXPRESS ]   ZNF490 [ SEEK ]   ZNF490 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF490 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF490 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57474
GTEX Portal (Tissue expression)ZNF490
Human Protein AtlasENSG00000188033-ZNF490 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULM2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULM2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULM2
Splice isoforms : SwissVarQ9ULM2
PhosPhoSitePlusQ9ULM2
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF490
Blocks (Seattle)ZNF490
SuperfamilyQ9ULM2
Human Protein Atlas [tissue]ENSG00000188033-ZNF490 [tissue]
Peptide AtlasQ9ULM2
HPRD15802
IPIIPI00012282   IPI00924968   IPI00924742   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULM2
IntAct (EBI)Q9ULM2
BioGRIDZNF490
STRING (EMBL)ZNF490
ZODIACZNF490
Ontologies - Pathways
QuickGOQ9ULM2
Ontology : AmiGODNA binding  protein binding  nucleus  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF490
Atlas of Cancer Signalling NetworkZNF490
Wikipedia pathwaysZNF490
Orthology - Evolution
OrthoDB57474
GeneTree (enSembl)ENSG00000188033
Phylogenetic Trees/Animal Genes : TreeFamZNF490
HOGENOMQ9ULM2
Homologs : HomoloGeneZNF490
Homology/Alignments : Family Browser (UCSC)ZNF490
Gene fusions - Rearrangements
Fusion : MitelmanITSN1/ZNF490 [21q22.11/19p13.2]  
Fusion : MitelmanZNF490/ITSN1 [19p13.2/21q22.11]  
Fusion : QuiverZNF490
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF490 [hg38]
dbVarZNF490
ClinVarZNF490
MonarchZNF490
1000_GenomesZNF490 
Exome Variant ServerZNF490
GNOMAD BrowserENSG00000188033
Varsome BrowserZNF490
Genomic Variants (DGV)ZNF490 [DGVbeta]
DECIPHERZNF490 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF490 
Mutations
ICGC Data PortalZNF490 
TCGA Data PortalZNF490 
Broad Tumor PortalZNF490
OASIS PortalZNF490 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF490  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF490
Mutations and Diseases : HGMDZNF490
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF490
DgiDB (Drug Gene Interaction Database)ZNF490
DoCM (Curated mutations)ZNF490 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF490 (select a term)
intoGenZNF490
Cancer3DZNF490(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF490
MedgenZNF490
Genetic Testing Registry ZNF490
NextProtQ9ULM2 [Medical]
GENETestsZNF490
Target ValidationZNF490
Huge Navigator ZNF490 [HugePedia]
ClinGenZNF490
Clinical trials, drugs, therapy
MyCancerGenomeZNF490
Protein Interactions : CTD
Pharm GKB GenePA134990049
PharosQ9ULM2
Clinical trialZNF490
Miscellaneous
canSAR (ICR)ZNF490 (select the gene name)
HarmonizomeZNF490
DataMed IndexZNF490
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF490
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jan 1 18:45:21 CET 2021
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