Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ZNF490 (zinc finger protein 490)

Identity

Alias_symbol (synonym)KIAA1198
Other alias-
HGNC (Hugo) ZNF490
LocusID (NCBI) 57474
Atlas_Id 54806
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 12576106 and ends at 12610809 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ITSN1 (21q22.11) / ZNF490 (19p13.2)ZNF490 (19p13.2) / ITSN1 (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ZNF490   23705
Cards
Entrez_Gene (NCBI)ZNF490  57474  zinc finger protein 490
Aliases
GeneCards (Weizmann)ZNF490
Ensembl hg19 (Hinxton)ENSG00000188033 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188033 [Gene_View]  chr19:12576106-12610809 [Contig_View]  ZNF490 [Vega]
ICGC DataPortalENSG00000188033
TCGA cBioPortalZNF490
AceView (NCBI)ZNF490
Genatlas (Paris)ZNF490
WikiGenes57474
SOURCE (Princeton)ZNF490
Genetics Home Reference (NIH)ZNF490
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF490  -     chr19:12576106-12610809 -  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF490  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblZNF490 - 19p13.2 [CytoView hg19]  ZNF490 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIZNF490 [Mapview hg19]  ZNF490 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB033024 BC038586 EU446833
RefSeq transcript (Entrez)NM_020714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF490
Cluster EST : UnigeneHs.655860 [ NCBI ]
CGAP (NCI)Hs.655860
Alternative Splicing GalleryENSG00000188033
Gene ExpressionZNF490 [ NCBI-GEO ]   ZNF490 [ EBI - ARRAY_EXPRESS ]   ZNF490 [ SEEK ]   ZNF490 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF490 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57474
GTEX Portal (Tissue expression)ZNF490
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULM2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULM2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULM2
Splice isoforms : SwissVarQ9ULM2
PhosPhoSitePlusQ9ULM2
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam01352    pfam13912   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF490
DMDM Disease mutations57474
Blocks (Seattle)ZNF490
SuperfamilyQ9ULM2
Human Protein AtlasENSG00000188033
Peptide AtlasQ9ULM2
HPRD15802
IPIIPI00012282   IPI00924968   IPI00924742   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULM2
IntAct (EBI)Q9ULM2
FunCoupENSG00000188033
BioGRIDZNF490
STRING (EMBL)ZNF490
ZODIACZNF490
Ontologies - Pathways
QuickGOQ9ULM2
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF490
Atlas of Cancer Signalling NetworkZNF490
Wikipedia pathwaysZNF490
Orthology - Evolution
OrthoDB57474
GeneTree (enSembl)ENSG00000188033
Phylogenetic Trees/Animal Genes : TreeFamZNF490
HOVERGENQ9ULM2
HOGENOMQ9ULM2
Homologs : HomoloGeneZNF490
Homology/Alignments : Family Browser (UCSC)ZNF490
Gene fusions - Rearrangements
Fusion : MitelmanITSN1/ZNF490 [21q22.11/19p13.2]  [t(19;21)(p13;q22)]  
Fusion : MitelmanZNF490/ITSN1 [19p13.2/21q22.11]  [t(19;21)(p13;q22)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF490 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF490
dbVarZNF490
ClinVarZNF490
1000_GenomesZNF490 
Exome Variant ServerZNF490
ExAC (Exome Aggregation Consortium)ZNF490 (select the gene name)
Genetic variants : HAPMAP57474
Genomic Variants (DGV)ZNF490 [DGVbeta]
DECIPHERZNF490 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF490 
Mutations
ICGC Data PortalZNF490 
TCGA Data PortalZNF490 
Broad Tumor PortalZNF490
OASIS PortalZNF490 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF490  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF490
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF490
DgiDB (Drug Gene Interaction Database)ZNF490
DoCM (Curated mutations)ZNF490 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF490 (select a term)
intoGenZNF490
Cancer3DZNF490(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF490
Genetic Testing Registry ZNF490
NextProtQ9ULM2 [Medical]
TSGene57474
GENETestsZNF490
Target ValidationZNF490
Huge Navigator ZNF490 [HugePedia]
snp3D : Map Gene to Disease57474
BioCentury BCIQZNF490
ClinGenZNF490
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57474
Chemical/Pharm GKB GenePA134990049
Clinical trialZNF490
Miscellaneous
canSAR (ICR)ZNF490 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF490
EVEXZNF490
GoPubMedZNF490
iHOPZNF490
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:49 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.