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ZNF492 (zinc finger protein 492)

Identity

Alias_namesZNF115
zinc finger protein 115 (Y20)
Alias_symbol (synonym)KIAA1473
Other alias
HGNC (Hugo) ZNF492
LocusID (NCBI) 57615
Atlas_Id 54807
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 22634324 and ends at 22667670 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
UNC13A (19p13.11) / ZNF492 (19p12)ZNF492 (19p12) / NLRP5 (19q13.43)ZNF492 19p12 / NLRP5 19q13.43

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(19;19)(p12;q13) ZNF492/NLRP5
t(19;19)(p13;p12) UNC13A/ZNF492


External links

Nomenclature
HGNC (Hugo)ZNF492   23707
Cards
Entrez_Gene (NCBI)ZNF492  57615  zinc finger protein 492
AliasesZNF115
GeneCards (Weizmann)ZNF492
Ensembl hg19 (Hinxton)ENSG00000229676 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000229676 [Gene_View]  ENSG00000229676 [Sequence]  chr19:22634324-22667670 [Contig_View]  ZNF492 [Vega]
ICGC DataPortalENSG00000229676
TCGA cBioPortalZNF492
AceView (NCBI)ZNF492
Genatlas (Paris)ZNF492
WikiGenes57615
SOURCE (Princeton)ZNF492
Genetics Home Reference (NIH)ZNF492
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF492  -     chr19:22634324-22667670 +  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF492  -     19p12   [Description]    (hg19-Feb_2009)
ZNF492 - 19p12 [CytoView hg19]  ZNF492 - 19p12 [CytoView hg38]
Mapping of homologs : NCBIZNF492 [Mapview hg19]  ZNF492 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB040906 BC110575 BP871882
RefSeq transcript (Entrez)NM_020855
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF492
Cluster EST : UnigeneHs.232108 [ NCBI ]
CGAP (NCI)Hs.232108
Alternative Splicing GalleryENSG00000229676
Gene ExpressionZNF492 [ NCBI-GEO ]   ZNF492 [ EBI - ARRAY_EXPRESS ]   ZNF492 [ SEEK ]   ZNF492 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF492 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57615
GTEX Portal (Tissue expression)ZNF492
Human Protein AtlasENSG00000229676-ZNF492 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P255   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P255  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P255
Splice isoforms : SwissVarQ9P255
PhosPhoSitePlusQ9P255
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF492
DMDM Disease mutations57615
Blocks (Seattle)ZNF492
SuperfamilyQ9P255
Human Protein Atlas [tissue]ENSG00000229676-ZNF492 [tissue]
Peptide AtlasQ9P255
IPIIPI00847858   
Protein Interaction databases
DIP (DOE-UCLA)Q9P255
IntAct (EBI)Q9P255
FunCoupENSG00000229676
BioGRIDZNF492
STRING (EMBL)ZNF492
ZODIACZNF492
Ontologies - Pathways
QuickGOQ9P255
Ontology : AmiGODNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBIDNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF492
Atlas of Cancer Signalling NetworkZNF492
Wikipedia pathwaysZNF492
Orthology - Evolution
OrthoDB57615
GeneTree (enSembl)ENSG00000229676
Phylogenetic Trees/Animal Genes : TreeFamZNF492
HOGENOMQ9P255
Homologs : HomoloGeneZNF492
Homology/Alignments : Family Browser (UCSC)ZNF492
Gene fusions - Rearrangements
Fusion : MitelmanUNC13A/ZNF492 [19p13.11/19p12]  [t(19;19)(p12;p13)]  
Fusion : MitelmanZNF492/NLRP5 [19p12/19q13.43]  [t(19;19)(p12;q13)]  
Fusion PortalZNF492 19p12 NLRP5 19q13.43 BRCA
Fusion : QuiverZNF492
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF492 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF492
dbVarZNF492
ClinVarZNF492
1000_GenomesZNF492 
Exome Variant ServerZNF492
ExAC (Exome Aggregation Consortium)ENSG00000229676
GNOMAD BrowserENSG00000229676
Varsome BrowserZNF492
Genetic variants : HAPMAP57615
Genomic Variants (DGV)ZNF492 [DGVbeta]
DECIPHERZNF492 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF492 
Mutations
ICGC Data PortalZNF492 
TCGA Data PortalZNF492 
Broad Tumor PortalZNF492
OASIS PortalZNF492 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF492  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF492
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF492
DgiDB (Drug Gene Interaction Database)ZNF492
DoCM (Curated mutations)ZNF492 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF492 (select a term)
intoGenZNF492
Cancer3DZNF492(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF492
MedgenZNF492
Genetic Testing Registry ZNF492
NextProtQ9P255 [Medical]
TSGene57615
GENETestsZNF492
Target ValidationZNF492
Huge Navigator ZNF492 [HugePedia]
snp3D : Map Gene to Disease57615
BioCentury BCIQZNF492
ClinGenZNF492
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57615
Chemical/Pharm GKB GenePA134940205
Clinical trialZNF492
Miscellaneous
canSAR (ICR)ZNF492 (select the gene name)
DataMed IndexZNF492
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF492
EVEXZNF492
GoPubMedZNF492
iHOPZNF492
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu May 2 13:18:13 CEST 2019

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