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ZNF557 (zinc finger protein 557)

Identity

Alias (NCBI)-
HGNC (Hugo) ZNF557
HGNC Alias symbMGC4054
LocusID (NCBI) 79230
Atlas_Id 76233
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 7069703 and ends at 7087967 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZNF557 (19p13.2)::SIGLECL1 (19q13.41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF557   28632
Cards
Entrez_Gene (NCBI)ZNF557    zinc finger protein 557
Aliases
GeneCards (Weizmann)ZNF557
Ensembl hg19 (Hinxton)ENSG00000130544 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130544 [Gene_View]  ENSG00000130544 [Sequence]  chr19:7069703-7087967 [Contig_View]  ZNF557 [Vega]
ICGC DataPortalENSG00000130544
TCGA cBioPortalZNF557
AceView (NCBI)ZNF557
Genatlas (Paris)ZNF557
SOURCE (Princeton)ZNF557
Genetics Home Reference (NIH)ZNF557
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF557  -     chr19:7069703-7087967 +  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF557  -     19p13.2   [Description]    (hg19-Feb_2009)
GoldenPathZNF557 - 19p13.2 [CytoView hg19]  ZNF557 - 19p13.2 [CytoView hg38]
ImmunoBaseENSG00000130544
Genome Data Viewer NCBIZNF557 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK095524 AK297283 AK315405 BC003020 BC031208
RefSeq transcript (Entrez)NM_001044387 NM_001044388 NM_024341
Consensus coding sequences : CCDS (NCBI)ZNF557
Gene ExpressionZNF557 [ NCBI-GEO ]   ZNF557 [ EBI - ARRAY_EXPRESS ]   ZNF557 [ SEEK ]   ZNF557 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF557 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF557 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79230
GTEX Portal (Tissue expression)ZNF557
Human Protein AtlasENSG00000130544-ZNF557 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N988   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N988  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N988
PhosPhoSitePlusQ8N988
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF557
SuperfamilyQ8N988
AlphaFold pdb e-kbQ8N988   
Human Protein Atlas [tissue]ENSG00000130544-ZNF557 [tissue]
HPRD15840
Protein Interaction databases
DIP (DOE-UCLA)Q8N988
IntAct (EBI)Q8N988
BioGRIDZNF557
STRING (EMBL)ZNF557
ZODIACZNF557
Ontologies - Pathways
QuickGOQ8N988
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II transcription regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  nucleus  regulation of transcription by RNA polymerase II  metal ion binding  
NDEx NetworkZNF557
Atlas of Cancer Signalling NetworkZNF557
Wikipedia pathwaysZNF557
Orthology - Evolution
OrthoDB79230
GeneTree (enSembl)ENSG00000130544
Phylogenetic Trees/Animal Genes : TreeFamZNF557
Homologs : HomoloGeneZNF557
Homology/Alignments : Family Browser (UCSC)ZNF557
Gene fusions - Rearrangements
Fusion : QuiverZNF557
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF557 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF557
dbVarZNF557
ClinVarZNF557
MonarchZNF557
1000_GenomesZNF557 
Exome Variant ServerZNF557
GNOMAD BrowserENSG00000130544
Varsome BrowserZNF557
ACMGZNF557 variants
VarityQ8N988
Genomic Variants (DGV)ZNF557 [DGVbeta]
DECIPHERZNF557 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF557 
Mutations
ICGC Data PortalZNF557 
TCGA Data PortalZNF557 
Broad Tumor PortalZNF557
OASIS PortalZNF557 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF557  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF557
Mutations and Diseases : HGMDZNF557
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF557
DgiDB (Drug Gene Interaction Database)ZNF557
DoCM (Curated mutations)ZNF557
CIViC (Clinical Interpretations of Variants in Cancer)ZNF557
Cancer3DZNF557
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF557
MedgenZNF557
Genetic Testing Registry ZNF557
NextProtQ8N988 [Medical]
GENETestsZNF557
Target ValidationZNF557
Huge Navigator ZNF557 [HugePedia]
ClinGenZNF557
Clinical trials, drugs, therapy
MyCancerGenomeZNF557
Protein Interactions : CTDZNF557
Pharm GKB GenePA134866521
PharosQ8N988
Clinical trialZNF557
Miscellaneous
canSAR (ICR)ZNF557
HarmonizomeZNF557
ARCHS4ZNF557
DataMed IndexZNF557
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF557
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 14:00:00 CET 2022

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