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ZNF577 (zinc finger protein 577)

Identity

Alias_symbol (synonym)MGC4400
Other alias-
HGNC (Hugo) ZNF577
LocusID (NCBI) 84765
Atlas_Id 52496
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 52374551 and ends at 52391189 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SIN3A (15q24.2) / ZNF577 (19q13.41)ZNF577 (19q13.41) / FGFR1 (8p11.23)ZNF577 (19q13.41) / GRIK5 (19q13.2)
ZNF577 (19q13.41) / ZNF649 (19q13.41)ZNF649 (19q13.41) / ZNF577 (19q13.41)ZNF577 19q13.41 / GRIK5 19q13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prostate tumors: an overview


External links

Nomenclature
HGNC (Hugo)ZNF577   28673
Cards
Entrez_Gene (NCBI)ZNF577  84765  zinc finger protein 577
Aliases
GeneCards (Weizmann)ZNF577
Ensembl hg19 (Hinxton)ENSG00000161551 [Gene_View]  chr19:52374551-52391189 [Contig_View]  ZNF577 [Vega]
Ensembl hg38 (Hinxton)ENSG00000161551 [Gene_View]  chr19:52374551-52391189 [Contig_View]  ZNF577 [Vega]
ICGC DataPortalENSG00000161551
TCGA cBioPortalZNF577
AceView (NCBI)ZNF577
Genatlas (Paris)ZNF577
WikiGenes84765
SOURCE (Princeton)ZNF577
Genetics Home Reference (NIH)ZNF577
Genomic and cartography
GoldenPath hg19 (UCSC)ZNF577  -     chr19:52374551-52391189 -  19q13.41   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZNF577  -     19q13.41   [Description]    (hg38-Dec_2013)
EnsemblZNF577 - 19q13.41 [CytoView hg19]  ZNF577 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBIZNF577 [Mapview hg19]  ZNF577 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK056853 AK093036 AK289479 AK291812 AL832871
RefSeq transcript (Entrez)NM_001135590 NM_032679
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)ZNF577
Cluster EST : UnigeneHs.729135 [ NCBI ]
CGAP (NCI)Hs.729135
Alternative Splicing GalleryENSG00000161551
Gene ExpressionZNF577 [ NCBI-GEO ]   ZNF577 [ EBI - ARRAY_EXPRESS ]   ZNF577 [ SEEK ]   ZNF577 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF577 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84765
GTEX Portal (Tissue expression)ZNF577
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BSK1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BSK1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BSK1
Splice isoforms : SwissVarQ9BSK1
PhosPhoSitePlusQ9BSK1
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF577
DMDM Disease mutations84765
Blocks (Seattle)ZNF577
SuperfamilyQ9BSK1
Human Protein AtlasENSG00000161551
Peptide AtlasQ9BSK1
HPRD15856
IPIIPI00953310   IPI00646841   IPI00925509   IPI00925129   IPI00924878   IPI00925122   IPI00924530   
Protein Interaction databases
DIP (DOE-UCLA)Q9BSK1
IntAct (EBI)Q9BSK1
FunCoupENSG00000161551
BioGRIDZNF577
STRING (EMBL)ZNF577
ZODIACZNF577
Ontologies - Pathways
QuickGOQ9BSK1
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF577
Atlas of Cancer Signalling NetworkZNF577
Wikipedia pathwaysZNF577
Orthology - Evolution
OrthoDB84765
GeneTree (enSembl)ENSG00000161551
Phylogenetic Trees/Animal Genes : TreeFamZNF577
HOVERGENQ9BSK1
HOGENOMQ9BSK1
Homologs : HomoloGeneZNF577
Homology/Alignments : Family Browser (UCSC)ZNF577
Gene fusions - Rearrangements
Fusion : MitelmanZNF577/GRIK5 [19q13.41/19q13.2]  
Fusion : MitelmanZNF649/ZNF577 [19q13.41/19q13.41]  [t(19;19)(q13;q13)]  
Fusion: TCGAZNF577 19q13.41 GRIK5 19q13.2 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF577 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF577
dbVarZNF577
ClinVarZNF577
1000_GenomesZNF577 
Exome Variant ServerZNF577
ExAC (Exome Aggregation Consortium)ZNF577 (select the gene name)
Genetic variants : HAPMAP84765
Genomic Variants (DGV)ZNF577 [DGVbeta]
DECIPHER (Syndromes)19:52374551-52391189  ENSG00000161551
CONAN: Copy Number AnalysisZNF577 
Mutations
ICGC Data PortalZNF577 
TCGA Data PortalZNF577 
Broad Tumor PortalZNF577
OASIS PortalZNF577 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF577  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF577
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF577
DgiDB (Drug Gene Interaction Database)ZNF577
DoCM (Curated mutations)ZNF577 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF577 (select a term)
intoGenZNF577
Cancer3DZNF577(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF577
Genetic Testing Registry ZNF577
NextProtQ9BSK1 [Medical]
TSGene84765
GENETestsZNF577
Huge Navigator ZNF577 [HugePedia]
snp3D : Map Gene to Disease84765
BioCentury BCIQZNF577
ClinGenZNF577
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84765
Chemical/Pharm GKB GenePA134942499
Clinical trialZNF577
Miscellaneous
canSAR (ICR)ZNF577 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF577
EVEXZNF577
GoPubMedZNF577
iHOPZNF577
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:25:49 CEST 2017

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