ZNF580 (zinc finger protein 580)

2012-02-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 51157
MIM: 617888
HGNC: 29473
Ensembl: ENSG00000213015

Variants:

dbSNP: 51157
ClinVar: 51157
TCGA: ENSG00000213015
COSMIC: ZNF580

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213015ENST00000325333Q9UK33
ENSG00000213015ENST00000543039Q9UK33
ENSG00000213015ENST00000545125Q9UK33
ENSG00000213015ENST00000590190K7EJ53
ENSG00000213015ENST00000592461K7ENY2
ENSG00000213015ENST00000592881K7ERU0

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203821202010Sphingosine-1-phosphate induces human endothelial VEGF and MMP-2 production via transcription factor ZNF580: novel insights into angiogenesis.20
218300642012ROS-induced ZNF580 expression: a key role for H2O2/NF-κB signaling pathway in vascular endothelial inflammation.8
215996572011ZNF580, a novel C2H2 zinc-finger transcription factor, interacts with the TGF-β signal molecule Smad2.6
247710662014ZNF580 mediates eNOS expression and endothelial cell migration/proliferation via the TGF-β1/ALK5/Smad2 pathway.4
213104142011Suppression of zinc finger protein 580 by high oxLDL/LDL-ratios is followed by enhanced expression of endothelial IL-8.2

Citation

Dessen P

ZNF580 (zinc finger protein 580)

Atlas Genet Cytogenet Oncol Haematol. 2012-02-01

Online version: http://atlasgeneticsoncology.org/gene/52586/znf580