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ZNF595 (zinc finger protein 595)

Identity

Alias_symbol (synonym)FLJ31740
Other alias-
HGNC (Hugo) ZNF595
LocusID (NCBI) 152687
Atlas_Id 54811
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 53179 and ends at 88099 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARHGEF10L (1p36.13) / ZNF595 (4p16.3)ATP11B (3q26.33) / ZNF595 (4p16.3)FASN (17q25.3) / ZNF595 (4p16.3)
KPNB1 (17q21.32) / ZNF595 (4p16.3)RARA (17q21.2) / ZNF595 (4p16.3)ZNF595 (4p16.3) / ATP11B (3q26.33)
ZNF595 (4p16.3) / PIGG (4p16.3)FASN 17q25.3 / ZNF595 4p16.3RARA 17q21.2 / ZNF595 4p16.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ZNF595   27196
Cards
Entrez_Gene (NCBI)ZNF595  152687  zinc finger protein 595
Aliases
GeneCards (Weizmann)ZNF595
Ensembl hg19 (Hinxton)ENSG00000272602 [Gene_View]  chr4:53179-88099 [Contig_View]  ZNF595 [Vega]
Ensembl hg38 (Hinxton)ENSG00000272602 [Gene_View]  chr4:53179-88099 [Contig_View]  ZNF595 [Vega]
ICGC DataPortalENSG00000272602
TCGA cBioPortalZNF595
AceView (NCBI)ZNF595
Genatlas (Paris)ZNF595
WikiGenes152687
SOURCE (Princeton)ZNF595
Genetics Home Reference (NIH)ZNF595
Genomic and cartography
GoldenPath hg19 (UCSC)ZNF595  -     chr4:53179-88099 +  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZNF595  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblZNF595 - 4p16.3 [CytoView hg19]  ZNF595 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBIZNF595 [Mapview hg19]  ZNF595 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK056302 AK300505 AK301848 AK309855 AK311343
RefSeq transcript (Entrez)NM_001286052 NM_001286053 NM_001286054 NM_182524
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_033822 NT_006051 NW_004929313
Consensus coding sequences : CCDS (NCBI)ZNF595
Cluster EST : UnigeneHs.709469 [ NCBI ]
CGAP (NCI)Hs.709469
Alternative Splicing GalleryENSG00000272602
Gene ExpressionZNF595 [ NCBI-GEO ]   ZNF595 [ EBI - ARRAY_EXPRESS ]   ZNF595 [ SEEK ]   ZNF595 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF595 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)152687
GTEX Portal (Tissue expression)ZNF595
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYB9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYB9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYB9
Splice isoforms : SwissVarQ8IYB9
PhosPhoSitePlusQ8IYB9
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam01352    pfam00096    pfam13912   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF595
DMDM Disease mutations152687
Blocks (Seattle)ZNF595
SuperfamilyQ8IYB9
Human Protein AtlasENSG00000272602
Peptide AtlasQ8IYB9
HPRD15868
IPIIPI00478170   IPI01008850   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYB9
IntAct (EBI)Q8IYB9
FunCoupENSG00000272602
BioGRIDZNF595
STRING (EMBL)ZNF595
ZODIACZNF595
Ontologies - Pathways
QuickGOQ8IYB9
Ontology : AmiGODNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF595
Atlas of Cancer Signalling NetworkZNF595
Wikipedia pathwaysZNF595
Orthology - Evolution
OrthoDB152687
GeneTree (enSembl)ENSG00000272602
Phylogenetic Trees/Animal Genes : TreeFamZNF595
HOVERGENQ8IYB9
HOGENOMQ8IYB9
Homologs : HomoloGeneZNF595
Homology/Alignments : Family Browser (UCSC)ZNF595
Gene fusions - Rearrangements
Fusion : MitelmanATP11B/ZNF595 [3q26.33/4p16.3]  [t(3;4)(q26;p16)]  
Fusion : MitelmanFASN/ZNF595 [17q25.3/4p16.3]  [t(4;17)(p16;q25)]  
Fusion : MitelmanRARA/ZNF595 [17q21.2/4p16.3]  [t(4;17)(p16;q21)]  
Fusion : MitelmanZNF595/ATP11B [4p16.3/3q26.33]  [t(3;4)(q26;p16)]  
Fusion: TCGAFASN 17q25.3 ZNF595 4p16.3 LUAD
Fusion: TCGARARA 17q21.2 ZNF595 4p16.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF595 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF595
dbVarZNF595
ClinVarZNF595
1000_GenomesZNF595 
Exome Variant ServerZNF595
ExAC (Exome Aggregation Consortium)ZNF595 (select the gene name)
Genetic variants : HAPMAP152687
Genomic Variants (DGV)ZNF595 [DGVbeta]
DECIPHER (Syndromes)4:53179-88099  ENSG00000272602
CONAN: Copy Number AnalysisZNF595 
Mutations
ICGC Data PortalZNF595 
TCGA Data PortalZNF595 
Broad Tumor PortalZNF595
OASIS PortalZNF595 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF595  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF595
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF595
DgiDB (Drug Gene Interaction Database)ZNF595
DoCM (Curated mutations)ZNF595 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF595 (select a term)
intoGenZNF595
Cancer3DZNF595(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF595
Genetic Testing Registry ZNF595
NextProtQ8IYB9 [Medical]
TSGene152687
GENETestsZNF595
Huge Navigator ZNF595 [HugePedia]
snp3D : Map Gene to Disease152687
BioCentury BCIQZNF595
ClinGenZNF595
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD152687
Chemical/Pharm GKB GenePA134868351
Clinical trialZNF595
Miscellaneous
canSAR (ICR)ZNF595 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF595
EVEXZNF595
GoPubMedZNF595
iHOPZNF595
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:35:10 CET 2017

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