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ZNF649 (zinc finger protein 649)

Identity

Other names-
HGNC (Hugo) ZNF649
LocusID (NCBI) 65251
Atlas_Id 49939
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 52392488 and ends at 52408305 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MRPL33 (2p23.2) / ZNF649 (19q13.41)ZNF577 (19q13.41) / ZNF649 (19q13.41)ZNF649 (19q13.41) / ZNF577 (19q13.41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 0 ]
  Prostate tumors: an overview

External links

Nomenclature
HGNC (Hugo)ZNF649   25741
Cards
Entrez_Gene (NCBI)ZNF649  65251  zinc finger protein 649
Aliases
GeneCards (Weizmann)ZNF649
Ensembl hg19 (Hinxton)ENSG00000198093 [Gene_View]  chr19:52392488-52408305 [Contig_View]  ZNF649 [Vega]
Ensembl hg38 (Hinxton)ENSG00000198093 [Gene_View]  chr19:52392488-52408305 [Contig_View]  ZNF649 [Vega]
ICGC DataPortalENSG00000198093
TCGA cBioPortalZNF649
AceView (NCBI)ZNF649
Genatlas (Paris)ZNF649
WikiGenes65251
SOURCE (Princeton)ZNF649
Genomic and cartography
GoldenPath hg19 (UCSC)ZNF649  -     chr19:52392488-52408305 -  19q13.41   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ZNF649  -     19q13.41   [Description]    (hg38-Dec_2013)
EnsemblZNF649 - 19q13.41 [CytoView hg19]  ZNF649 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBIZNF649 [Mapview hg19]  ZNF649 [Mapview hg38]
OMIM611903   
Gene and transcription
Genbank (Entrez)AF086241 AK000909 AK022706 AK225480 AK315487
RefSeq transcript (Entrez)NM_023074
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)ZNF649
Cluster EST : UnigeneHs.148322 [ NCBI ]
CGAP (NCI)Hs.148322
Alternative Splicing GalleryENSG00000198093
Gene ExpressionZNF649 [ NCBI-GEO ]   ZNF649 [ EBI - ARRAY_EXPRESS ]   ZNF649 [ SEEK ]   ZNF649 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF649 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65251
GTEX Portal (Tissue expression)ZNF649
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BS31 (Uniprot)
NextProtQ9BS31  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BS31
Splice isoforms : SwissVarQ9BS31 (Swissvar)
PhosPhoSitePlusQ9BS31
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam01352    pfam00096    pfam13912   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
DMDM Disease mutations65251
Blocks (Seattle)ZNF649
SuperfamilyQ9BS31
Human Protein AtlasENSG00000198093
Peptide AtlasQ9BS31
HPRD07785
IPIIPI00011987   
Protein Interaction databases
DIP (DOE-UCLA)Q9BS31
IntAct (EBI)Q9BS31
FunCoupENSG00000198093
BioGRIDZNF649
STRING (EMBL)ZNF649
ZODIACZNF649
Ontologies - Pathways
QuickGOQ9BS31
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  transcription factor activity, sequence-specific DNA binding  protein binding  extracellular space  nucleus  transcription, DNA-templated  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  transcription factor activity, sequence-specific DNA binding  protein binding  extracellular space  nucleus  transcription, DNA-templated  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  
NDEx Network
Atlas of Cancer Signalling NetworkZNF649
Wikipedia pathwaysZNF649
Orthology - Evolution
OrthoDB65251
GeneTree (enSembl)ENSG00000198093
Phylogenetic Trees/Animal Genes : TreeFamZNF649
Homologs : HomoloGeneZNF649
Homology/Alignments : Family Browser (UCSC)ZNF649
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerZNF649 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF649
dbVarZNF649
ClinVarZNF649
1000_GenomesZNF649 
Exome Variant ServerZNF649
ExAC (Exome Aggregation Consortium)ZNF649 (select the gene name)
Genetic variants : HAPMAP65251
Genomic Variants (DGV)ZNF649 [DGVbeta]
Mutations
ICGC Data PortalZNF649 
TCGA Data PortalZNF649 
Broad Tumor PortalZNF649
OASIS PortalZNF649 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF649 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF649
DgiDB (Drug Gene Interaction Database)ZNF649
DoCM (Curated mutations)ZNF649 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF649 (select a term)
intoGenZNF649
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)19:52392488-52408305  ENSG00000198093
CONAN: Copy Number AnalysisZNF649 
Mutations and Diseases : HGMDZNF649
OMIM611903   
MedgenZNF649
Genetic Testing Registry ZNF649
NextProtQ9BS31 [Medical]
TSGene65251
GENETestsZNF649
Huge Navigator ZNF649 [HugePedia]
snp3D : Map Gene to Disease65251
BioCentury BCIQZNF649
ClinGenZNF649
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65251
Chemical/Pharm GKB GenePA143485678
Clinical trialZNF649
Miscellaneous
canSAR (ICR)ZNF649 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF649
EVEXZNF649
GoPubMedZNF649
iHOPZNF649
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 9 19:27:00 CEST 2016

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