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ZNF675 (zinc finger protein 675)

Identity

Alias (NCBI)TBZF
TIZ
HGNC (Hugo) ZNF675
HGNC Alias symbTIZ
TBZF
HGNC Alias nameTRAF6 inhibitory zinc finger
LocusID (NCBI) 171392
Atlas_Id 52291
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 23652801 and ends at 23687212 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CHST9 (18q11.2)::ZNF675 (19p12)ZNF675 (19p12)::BRCA1 (17q21.31)ZNF675 (19p12)::IGSF23 (19q13.31)
CHST9 18q11.2::ZNF675 19p12ZNF675 19p12::BRCA1 17q21.31ZNF675 19p12::IGSF23 19q13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF675   30768
Cards
Entrez_Gene (NCBI)ZNF675    zinc finger protein 675
AliasesTBZF; TIZ
GeneCards (Weizmann)ZNF675
Ensembl hg19 (Hinxton)ENSG00000197372 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197372 [Gene_View]  ENSG00000197372 [Sequence]  chr19:23652801-23687212 [Contig_View]  ZNF675 [Vega]
ICGC DataPortalENSG00000197372
TCGA cBioPortalZNF675
AceView (NCBI)ZNF675
Genatlas (Paris)ZNF675
SOURCE (Princeton)ZNF675
Genetics Home Reference (NIH)ZNF675
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF675  -     chr19:23652801-23687212 -  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF675  -     19p12   [Description]    (hg19-Feb_2009)
GoldenPathZNF675 - 19p12 [CytoView hg19]  ZNF675 - 19p12 [CytoView hg38]
ImmunoBaseENSG00000197372
Genome Data Viewer NCBIZNF675 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB209601 AK093669 AK307845 AY044432 BC032394
RefSeq transcript (Entrez)NM_138330
Consensus coding sequences : CCDS (NCBI)ZNF675
Gene ExpressionZNF675 [ NCBI-GEO ]   ZNF675 [ EBI - ARRAY_EXPRESS ]   ZNF675 [ SEEK ]   ZNF675 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF675 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF675 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)171392
GTEX Portal (Tissue expression)ZNF675
Human Protein AtlasENSG00000197372-ZNF675 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TD23   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TD23  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TD23
PhosPhoSitePlusQ8TD23
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF675
SuperfamilyQ8TD23
AlphaFold pdb e-kbQ8TD23   
Human Protein Atlas [tissue]ENSG00000197372-ZNF675 [tissue]
HPRD18193
Protein Interaction databases
DIP (DOE-UCLA)Q8TD23
IntAct (EBI)Q8TD23
BioGRIDZNF675
STRING (EMBL)ZNF675
ZODIACZNF675
Ontologies - Pathways
QuickGOQ8TD23
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  regulation of transcription, DNA-templated  I-kappaB kinase/NF-kappaB signaling  zinc ion binding  negative regulation of tumor necrosis factor-mediated signaling pathway  cytokine-mediated signaling pathway  ubiquitin protein ligase binding  negative regulation of NF-kappaB transcription factor activity  negative regulation of JUN kinase activity  bone resorption  negative regulation of osteoclast differentiation  negative regulation of JNK cascade  perinuclear region of cytoplasm  negative regulation of interleukin-1-mediated signaling pathway  negative regulation of transcription regulatory region DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  protein binding  nucleus  regulation of transcription, DNA-templated  I-kappaB kinase/NF-kappaB signaling  zinc ion binding  negative regulation of tumor necrosis factor-mediated signaling pathway  cytokine-mediated signaling pathway  ubiquitin protein ligase binding  negative regulation of NF-kappaB transcription factor activity  negative regulation of JUN kinase activity  bone resorption  negative regulation of osteoclast differentiation  negative regulation of JNK cascade  perinuclear region of cytoplasm  negative regulation of interleukin-1-mediated signaling pathway  negative regulation of transcription regulatory region DNA binding  
NDEx NetworkZNF675
Atlas of Cancer Signalling NetworkZNF675
Wikipedia pathwaysZNF675
Orthology - Evolution
OrthoDB171392
GeneTree (enSembl)ENSG00000197372
Phylogenetic Trees/Animal Genes : TreeFamZNF675
Homologs : HomoloGeneZNF675
Homology/Alignments : Family Browser (UCSC)ZNF675
Gene fusions - Rearrangements
Fusion : MitelmanCHST9::ZNF675 [18q11.2/19p12]  
Fusion : MitelmanZNF675::IGSF23 [19p12/19q13.31]  
Fusion : QuiverZNF675
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF675 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF675
dbVarZNF675
ClinVarZNF675
MonarchZNF675
1000_GenomesZNF675 
Exome Variant ServerZNF675
GNOMAD BrowserENSG00000197372
Varsome BrowserZNF675
ACMGZNF675 variants
VarityQ8TD23
Genomic Variants (DGV)ZNF675 [DGVbeta]
DECIPHERZNF675 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF675 
Mutations
ICGC Data PortalZNF675 
TCGA Data PortalZNF675 
Broad Tumor PortalZNF675
OASIS PortalZNF675 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF675  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF675
Mutations and Diseases : HGMDZNF675
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF675
DgiDB (Drug Gene Interaction Database)ZNF675
DoCM (Curated mutations)ZNF675
CIViC (Clinical Interpretations of Variants in Cancer)ZNF675
Cancer3DZNF675
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZNF675
MedgenZNF675
Genetic Testing Registry ZNF675
NextProtQ8TD23 [Medical]
GENETestsZNF675
Target ValidationZNF675
Huge Navigator ZNF675 [HugePedia]
ClinGenZNF675
Clinical trials, drugs, therapy
MyCancerGenomeZNF675
Protein Interactions : CTDZNF675
Pharm GKB GenePA142670476
PharosQ8TD23
Clinical trialZNF675
Miscellaneous
canSAR (ICR)ZNF675
HarmonizomeZNF675
ARCHS4ZNF675
DataMed IndexZNF675
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF675
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 13:07:47 CET 2022

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