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ZNF675 (zinc finger protein 675)

Identity

Alias_symbol (synonym)TIZ
TBZF
Other alias
HGNC (Hugo) ZNF675
LocusID (NCBI) 171392
Atlas_Id 52291
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 23652906 and ends at 23687215 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CHST9 (18q11.2) / ZNF675 (19p12)ZNF675 (19p12) / BRCA1 (17q21.31)ZNF675 (19p12) / IGSF23 (19q13.31)
CHST9 18q11.2 / ZNF675 19p12ZNF675 19p12 / BRCA1 17q21.31ZNF675 19p12 / IGSF23 19q13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZNF675   30768
Cards
Entrez_Gene (NCBI)ZNF675  171392  zinc finger protein 675
AliasesTBZF; TIZ
GeneCards (Weizmann)ZNF675
Ensembl hg19 (Hinxton)ENSG00000197372 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197372 [Gene_View]  chr19:23652906-23687215 [Contig_View]  ZNF675 [Vega]
ICGC DataPortalENSG00000197372
TCGA cBioPortalZNF675
AceView (NCBI)ZNF675
Genatlas (Paris)ZNF675
WikiGenes171392
SOURCE (Princeton)ZNF675
Genetics Home Reference (NIH)ZNF675
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF675  -     chr19:23652906-23687215 -  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF675  -     19p12   [Description]    (hg19-Feb_2009)
EnsemblZNF675 - 19p12 [CytoView hg19]  ZNF675 - 19p12 [CytoView hg38]
Mapping of homologs : NCBIZNF675 [Mapview hg19]  ZNF675 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB209601 AK093669 AK307845 AY044432 BC032394
RefSeq transcript (Entrez)NM_138330
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF675
Cluster EST : UnigeneHs.264345 [ NCBI ]
CGAP (NCI)Hs.264345
Alternative Splicing GalleryENSG00000197372
Gene ExpressionZNF675 [ NCBI-GEO ]   ZNF675 [ EBI - ARRAY_EXPRESS ]   ZNF675 [ SEEK ]   ZNF675 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF675 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)171392
GTEX Portal (Tissue expression)ZNF675
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TD23   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TD23  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TD23
Splice isoforms : SwissVarQ8TD23
PhosPhoSitePlusQ8TD23
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam01352    pfam00096    pfam13912   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF675
DMDM Disease mutations171392
Blocks (Seattle)ZNF675
SuperfamilyQ8TD23
Human Protein AtlasENSG00000197372
Peptide AtlasQ8TD23
HPRD18193
IPIIPI00152427   
Protein Interaction databases
DIP (DOE-UCLA)Q8TD23
IntAct (EBI)Q8TD23
FunCoupENSG00000197372
BioGRIDZNF675
STRING (EMBL)ZNF675
ZODIACZNF675
Ontologies - Pathways
QuickGOQ8TD23
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  protein binding  nucleus  transcription, DNA-templated  I-kappaB kinase/NF-kappaB signaling  zinc ion binding  negative regulation of tumor necrosis factor-mediated signaling pathway  cytokine-mediated signaling pathway  ubiquitin protein ligase binding  negative regulation of NF-kappaB transcription factor activity  negative regulation of JUN kinase activity  bone resorption  negative regulation of osteoclast differentiation  negative regulation of JNK cascade  perinuclear region of cytoplasm  negative regulation of interleukin-1-mediated signaling pathway  negative regulation of transcription regulatory region DNA binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  protein binding  nucleus  transcription, DNA-templated  I-kappaB kinase/NF-kappaB signaling  zinc ion binding  negative regulation of tumor necrosis factor-mediated signaling pathway  cytokine-mediated signaling pathway  ubiquitin protein ligase binding  negative regulation of NF-kappaB transcription factor activity  negative regulation of JUN kinase activity  bone resorption  negative regulation of osteoclast differentiation  negative regulation of JNK cascade  perinuclear region of cytoplasm  negative regulation of interleukin-1-mediated signaling pathway  negative regulation of transcription regulatory region DNA binding  
NDEx NetworkZNF675
Atlas of Cancer Signalling NetworkZNF675
Wikipedia pathwaysZNF675
Orthology - Evolution
OrthoDB171392
GeneTree (enSembl)ENSG00000197372
Phylogenetic Trees/Animal Genes : TreeFamZNF675
HOVERGENQ8TD23
HOGENOMQ8TD23
Homologs : HomoloGeneZNF675
Homology/Alignments : Family Browser (UCSC)ZNF675
Gene fusions - Rearrangements
Fusion : MitelmanCHST9/ZNF675 [18q11.2/19p12]  [t(18;19)(q11;p12)]  
Fusion : MitelmanZNF675/IGSF23 [19p12/19q13.31]  [t(19;19)(p12;q13)]  
Fusion: TCGACHST9 18q11.2 ZNF675 19p12 LUSC
Fusion: TCGAZNF675 19p12 BRCA1 17q21.31 LUAD
Fusion: TCGAZNF675 19p12 IGSF23 19q13.31 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF675 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF675
dbVarZNF675
ClinVarZNF675
1000_GenomesZNF675 
Exome Variant ServerZNF675
ExAC (Exome Aggregation Consortium)ZNF675 (select the gene name)
Genetic variants : HAPMAP171392
Genomic Variants (DGV)ZNF675 [DGVbeta]
DECIPHERZNF675 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF675 
Mutations
ICGC Data PortalZNF675 
TCGA Data PortalZNF675 
Broad Tumor PortalZNF675
OASIS PortalZNF675 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF675  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF675
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF675
DgiDB (Drug Gene Interaction Database)ZNF675
DoCM (Curated mutations)ZNF675 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF675 (select a term)
intoGenZNF675
Cancer3DZNF675(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF675
Genetic Testing Registry ZNF675
NextProtQ8TD23 [Medical]
TSGene171392
GENETestsZNF675
Target ValidationZNF675
Huge Navigator ZNF675 [HugePedia]
snp3D : Map Gene to Disease171392
BioCentury BCIQZNF675
ClinGenZNF675
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD171392
Chemical/Pharm GKB GenePA142670476
Clinical trialZNF675
Miscellaneous
canSAR (ICR)ZNF675 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF675
EVEXZNF675
GoPubMedZNF675
iHOPZNF675
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:55 CEST 2017

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