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ZNF684 (zinc finger protein 684)

Identity

Alias_symbol (synonym)MGC27466
Other alias-
HGNC (Hugo) ZNF684
LocusID (NCBI) 127396
Atlas_Id 54813
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 40531561 and ends at 40548169 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCL2L1 (20q11.21) / ZNF684 (1p34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)ZNF684   28418
Cards
Entrez_Gene (NCBI)ZNF684  127396  zinc finger protein 684
Aliases
GeneCards (Weizmann)ZNF684
Ensembl hg19 (Hinxton)ENSG00000117010 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117010 [Gene_View]  chr1:40531561-40548169 [Contig_View]  ZNF684 [Vega]
ICGC DataPortalENSG00000117010
TCGA cBioPortalZNF684
AceView (NCBI)ZNF684
Genatlas (Paris)ZNF684
WikiGenes127396
SOURCE (Princeton)ZNF684
Genetics Home Reference (NIH)ZNF684
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF684  -     chr1:40531561-40548169 +  1p34.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF684  -     1p34.2   [Description]    (hg19-Feb_2009)
EnsemblZNF684 - 1p34.2 [CytoView hg19]  ZNF684 - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBIZNF684 [Mapview hg19]  ZNF684 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK094072 BC016016 BC091518 BC111463 BG116229
RefSeq transcript (Entrez)NM_152373
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF684
Cluster EST : UnigeneHs.524767 [ NCBI ]
CGAP (NCI)Hs.524767
Alternative Splicing GalleryENSG00000117010
Gene ExpressionZNF684 [ NCBI-GEO ]   ZNF684 [ EBI - ARRAY_EXPRESS ]   ZNF684 [ SEEK ]   ZNF684 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF684 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)127396
GTEX Portal (Tissue expression)ZNF684
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T5D7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T5D7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T5D7
Splice isoforms : SwissVarQ5T5D7
PhosPhoSitePlusQ5T5D7
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)    zf-C2H2_6 (PF13912)   
Domain families : Pfam (NCBI)pfam01352    pfam00096    pfam13912   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF684
DMDM Disease mutations127396
Blocks (Seattle)ZNF684
SuperfamilyQ5T5D7
Human Protein AtlasENSG00000117010
Peptide AtlasQ5T5D7
HPRD11328
IPIIPI00003271   IPI00514291   IPI00514785   
Protein Interaction databases
DIP (DOE-UCLA)Q5T5D7
IntAct (EBI)Q5T5D7
FunCoupENSG00000117010
BioGRIDZNF684
STRING (EMBL)ZNF684
ZODIACZNF684
Ontologies - Pathways
QuickGOQ5T5D7
Ontology : AmiGODNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBIDNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF684
Atlas of Cancer Signalling NetworkZNF684
Wikipedia pathwaysZNF684
Orthology - Evolution
OrthoDB127396
GeneTree (enSembl)ENSG00000117010
Phylogenetic Trees/Animal Genes : TreeFamZNF684
HOVERGENQ5T5D7
HOGENOMQ5T5D7
Homologs : HomoloGeneZNF684
Homology/Alignments : Family Browser (UCSC)ZNF684
Gene fusions - Rearrangements
Fusion : MitelmanBCL2L1/ZNF684 [20q11.21/1p34.2]  [t(1;20)(p34;q11)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF684 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF684
dbVarZNF684
ClinVarZNF684
1000_GenomesZNF684 
Exome Variant ServerZNF684
ExAC (Exome Aggregation Consortium)ZNF684 (select the gene name)
Genetic variants : HAPMAP127396
Genomic Variants (DGV)ZNF684 [DGVbeta]
DECIPHERZNF684 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF684 
Mutations
ICGC Data PortalZNF684 
TCGA Data PortalZNF684 
Broad Tumor PortalZNF684
OASIS PortalZNF684 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF684  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF684
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF684
DgiDB (Drug Gene Interaction Database)ZNF684
DoCM (Curated mutations)ZNF684 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF684 (select a term)
intoGenZNF684
Cancer3DZNF684(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenZNF684
Genetic Testing Registry ZNF684
NextProtQ5T5D7 [Medical]
TSGene127396
GENETestsZNF684
Target ValidationZNF684
Huge Navigator ZNF684 [HugePedia]
snp3D : Map Gene to Disease127396
BioCentury BCIQZNF684
ClinGenZNF684
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD127396
Chemical/Pharm GKB GenePA142670485
Clinical trialZNF684
Miscellaneous
canSAR (ICR)ZNF684 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF684
EVEXZNF684
GoPubMedZNF684
iHOPZNF684
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:03:55 CEST 2017

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