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ZNF703 (zinc finger protein 703)

Identity

Alias_symbol (synonym)FLJ14299
ZNF503L
NLZ1
Zpo1
ZEPPO1
Other aliasZPO1
HGNC (Hugo) ZNF703
LocusID (NCBI) 80139
Atlas_Id 52134
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 37695751 and ends at 37700021 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FGFR1 (8p11.23) / ZNF703 (8p11.23)ZNF703 (8p11.23) / ARSJ (4q26)ZNF703 (8p11.23) / DMKN (19q13.12)
FGFR1 8p11.23 / ZNF703 8p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Male breast cancer


External links

Nomenclature
HGNC (Hugo)ZNF703   25883
Cards
Entrez_Gene (NCBI)ZNF703  80139  zinc finger protein 703
AliasesNLZ1; ZEPPO1; ZNF503L; ZPO1
GeneCards (Weizmann)ZNF703
Ensembl hg19 (Hinxton)ENSG00000183779 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183779 [Gene_View]  chr8:37695751-37700021 [Contig_View]  ZNF703 [Vega]
ICGC DataPortalENSG00000183779
TCGA cBioPortalZNF703
AceView (NCBI)ZNF703
Genatlas (Paris)ZNF703
WikiGenes80139
SOURCE (Princeton)ZNF703
Genetics Home Reference (NIH)ZNF703
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF703  -     chr8:37695751-37700021 +  8p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF703  -     8p11.23   [Description]    (hg19-Feb_2009)
EnsemblZNF703 - 8p11.23 [CytoView hg19]  ZNF703 - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBIZNF703 [Mapview hg19]  ZNF703 [Mapview hg38]
OMIM617045   
Gene and transcription
Genbank (Entrez)AA527152 AK024361 BC032534 BC084581 BM770319
RefSeq transcript (Entrez)NM_025069
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF703
Cluster EST : UnigeneHs.744591 [ NCBI ]
CGAP (NCI)Hs.744591
Alternative Splicing GalleryENSG00000183779
Gene ExpressionZNF703 [ NCBI-GEO ]   ZNF703 [ EBI - ARRAY_EXPRESS ]   ZNF703 [ SEEK ]   ZNF703 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF703 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80139
GTEX Portal (Tissue expression)ZNF703
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H7S9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H7S9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H7S9
Splice isoforms : SwissVarQ9H7S9
PhosPhoSitePlusQ9H7S9
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Tscrpt_rep_NocA-like    Znf_C2H2    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)nlz1 (PF12402)   
Domain families : Pfam (NCBI)pfam12402   
Conserved Domain (NCBI)ZNF703
DMDM Disease mutations80139
Blocks (Seattle)ZNF703
SuperfamilyQ9H7S9
Human Protein AtlasENSG00000183779
Peptide AtlasQ9H7S9
HPRD07855
IPIIPI00017972   IPI00952921   
Protein Interaction databases
DIP (DOE-UCLA)Q9H7S9
IntAct (EBI)Q9H7S9
FunCoupENSG00000183779
BioGRIDZNF703
STRING (EMBL)ZNF703
ZODIACZNF703
Ontologies - Pathways
QuickGOQ9H7S9
Ontology : AmiGOnucleic acid binding  protein binding  nucleus  cytoplasm  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  positive regulation of cell proliferation  positive regulation of epithelial to mesenchymal transition  nuclear matrix  regulation of transforming growth factor beta receptor signaling pathway  positive regulation of cell migration  positive regulation of mammary gland epithelial cell proliferation  negative regulation of homotypic cell-cell adhesion  adherens junction assembly  protein complex  negative regulation of transcription, DNA-templated  metal ion binding  regulation of cell cycle  mammary gland epithelial cell differentiation  regulation of canonical Wnt signaling pathway  repressing transcription factor binding  cellular response to estradiol stimulus  
Ontology : EGO-EBInucleic acid binding  protein binding  nucleus  cytoplasm  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  positive regulation of cell proliferation  positive regulation of epithelial to mesenchymal transition  nuclear matrix  regulation of transforming growth factor beta receptor signaling pathway  positive regulation of cell migration  positive regulation of mammary gland epithelial cell proliferation  negative regulation of homotypic cell-cell adhesion  adherens junction assembly  protein complex  negative regulation of transcription, DNA-templated  metal ion binding  regulation of cell cycle  mammary gland epithelial cell differentiation  regulation of canonical Wnt signaling pathway  repressing transcription factor binding  cellular response to estradiol stimulus  
NDEx NetworkZNF703
Atlas of Cancer Signalling NetworkZNF703
Wikipedia pathwaysZNF703
Orthology - Evolution
OrthoDB80139
GeneTree (enSembl)ENSG00000183779
Phylogenetic Trees/Animal Genes : TreeFamZNF703
HOVERGENQ9H7S9
HOGENOMQ9H7S9
Homologs : HomoloGeneZNF703
Homology/Alignments : Family Browser (UCSC)ZNF703
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF703 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF703
dbVarZNF703
ClinVarZNF703
1000_GenomesZNF703 
Exome Variant ServerZNF703
ExAC (Exome Aggregation Consortium)ZNF703 (select the gene name)
Genetic variants : HAPMAP80139
Genomic Variants (DGV)ZNF703 [DGVbeta]
DECIPHERZNF703 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF703 
Mutations
ICGC Data PortalZNF703 
TCGA Data PortalZNF703 
Broad Tumor PortalZNF703
OASIS PortalZNF703 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF703  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF703
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF703
DgiDB (Drug Gene Interaction Database)ZNF703
DoCM (Curated mutations)ZNF703 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF703 (select a term)
intoGenZNF703
Cancer3DZNF703(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617045   
Orphanet
MedgenZNF703
Genetic Testing Registry ZNF703
NextProtQ9H7S9 [Medical]
TSGene80139
GENETestsZNF703
Target ValidationZNF703
Huge Navigator ZNF703 [HugePedia]
snp3D : Map Gene to Disease80139
BioCentury BCIQZNF703
ClinGenZNF703
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80139
Chemical/Pharm GKB GenePA142670500
Clinical trialZNF703
Miscellaneous
canSAR (ICR)ZNF703 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF703
EVEXZNF703
GoPubMedZNF703
iHOPZNF703
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:39:25 CEST 2017

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