| Nomenclature |
|---|
| HGNC (Hugo) | ZNF74 13144 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ZNF74 7625 zinc finger protein 74 |
| Aliases | COS52; ZFP520; ZNF520; hZNF7 |
| GeneCards (Weizmann) | ZNF74 |
| Ensembl hg19 (Hinxton) | ENSG00000185252 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000185252 [Gene_View] chr22:20394115-20408463 [Contig_View] ZNF74 [Vega] |
| ICGC DataPortal | ENSG00000185252 |
| TCGA cBioPortal | ZNF74 |
| AceView (NCBI) | ZNF74 |
| Genatlas (Paris) | ZNF74 |
| WikiGenes | 7625 |
| SOURCE (Princeton) | ZNF74 |
| Genetics Home Reference (NIH) | ZNF74 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ZNF74 - chr22:20394115-20408463 + 22q11.21 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ZNF74 - 22q11.21 [Description] (hg19-Feb_2009) |
| Ensembl | ZNF74 - 22q11.21 [CytoView hg19] ZNF74 - 22q11.21 [CytoView hg38] |
| Mapping of homologs : NCBI | ZNF74 [Mapview hg19] ZNF74 [Mapview hg38] |
| OMIM | 194548 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB209663 AK128267 AK291358 AK299569 BC013395 |
| RefSeq transcript (Entrez) | NM_001256523 NM_001256524 NM_001256525 NM_003426 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ZNF74 |
| Cluster EST : Unigene | Hs.517418 [ NCBI ] |
| CGAP (NCI) | Hs.517418 |
| Alternative Splicing Gallery | ENSG00000185252 |
| Gene Expression | ZNF74 [ NCBI-GEO ] ZNF74 [ EBI - ARRAY_EXPRESS ]
ZNF74 [ SEEK ] ZNF74 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ZNF74 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 7625 |
| GTEX Portal (Tissue expression) | ZNF74 |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q16587 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q16587 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q16587 |
| Splice isoforms : SwissVar | Q16587 |
| PhosPhoSitePlus | Q16587 |
| Domaine pattern : Prosite (Expaxy) | KRAB (PS50805) ZINC_FINGER_C2H2_1 (PS00028) ZINC_FINGER_C2H2_2 (PS50157) |
| Domains : Interpro (EBI) | KRAB Znf_C2H2 Znf_C2H2-like Znf_C2H2/integrase_DNA-bd |
| Domain families : Pfam (Sanger) | KRAB (PF01352) zf-C2H2 (PF00096) |
| Domain families : Pfam (NCBI) | pfam01352 pfam00096 |
| Domain families : Smart (EMBL) | KRAB (SM00349) ZnF_C2H2 (SM00355) |
| Conserved Domain (NCBI) | ZNF74 |
| DMDM Disease mutations | 7625 |
| Blocks (Seattle) | ZNF74 |
| Superfamily | Q16587 |
| Human Protein Atlas | ENSG00000185252 |
| Peptide Atlas | Q16587 |
| HPRD | 01928 |
| IPI | IPI00220139 IPI00807386 IPI00220140 IPI00480138 IPI00893344 IPI00892733 IPI00892603 IPI00892864 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q16587 |
| IntAct (EBI) | Q16587 |
| FunCoup | ENSG00000185252 |
| BioGRID | ZNF74 |
| STRING (EMBL) | ZNF74 |
| ZODIAC | ZNF74 |
| Ontologies - Pathways |
|---|
| QuickGO | Q16587 |
| Ontology : AmiGO | DNA binding transcription factor activity, sequence-specific DNA binding RNA binding nucleoplasm transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development actin cytoskeleton metal ion binding |
| Ontology : EGO-EBI | DNA binding transcription factor activity, sequence-specific DNA binding RNA binding nucleoplasm transcription, DNA-templated regulation of transcription, DNA-templated multicellular organism development actin cytoskeleton metal ion binding |
| NDEx Network | ZNF74 |
| Atlas of Cancer Signalling Network | ZNF74 |
| Wikipedia pathways | ZNF74 |
| Orthology - Evolution |
|---|
| OrthoDB | 7625 |
| GeneTree (enSembl) | ENSG00000185252 |
| Phylogenetic Trees/Animal Genes : TreeFam | ZNF74 |
| HOVERGEN | Q16587 |
| HOGENOM | Q16587 |
| Homologs : HomoloGene | ZNF74 |
| Homology/Alignments : Family Browser (UCSC) | ZNF74 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | KLHL22/ZNF74 [22q11.21/22q11.21] [t(22;22)(q11;q11)] |
| Fusion: TCGA | KLHL22 22q11.21 ZNF74 22q11.21 LUSC |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ZNF74 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ZNF74 |
| dbVar | ZNF74 |
| ClinVar | ZNF74 |
| 1000_Genomes | ZNF74 |
| Exome Variant Server | ZNF74 |
| ExAC (Exome Aggregation Consortium) | ZNF74 (select the gene name) |
| Genetic variants : HAPMAP | 7625 |
| Genomic Variants (DGV) | ZNF74 [DGVbeta] |
| DECIPHER | ZNF74 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ZNF74 |
| Mutations |
|---|
| ICGC Data Portal | ZNF74 |
| TCGA Data Portal | ZNF74 |
| Broad Tumor Portal | ZNF74 |
| OASIS Portal | ZNF74 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ZNF74 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | ZNF74 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search ZNF74 |
| DgiDB (Drug Gene Interaction Database) | ZNF74 |
| DoCM (Curated mutations) | ZNF74 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ZNF74 (select a term) |
| intoGen | ZNF74 |
| Cancer3D | ZNF74(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 194548 |
| Orphanet | |
| Medgen | ZNF74 |
| Genetic Testing Registry | ZNF74
|
| NextProt | Q16587 [Medical] |
| TSGene | 7625 |
| GENETests | ZNF74 |
| Huge Navigator |
ZNF74 [HugePedia] |
| snp3D : Map Gene to Disease | 7625 |
| BioCentury BCIQ | ZNF74 |
| ClinGen | ZNF74 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 7625 |
| Chemical/Pharm GKB Gene | PA37718 |
| Clinical trial | ZNF74 |
| Miscellaneous |
|---|
| canSAR (ICR) | ZNF74 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 14 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ZNF74 |
| EVEX | ZNF74 |
| GoPubMed | ZNF74 |
| iHOP | ZNF74 |
