ZNF750 (zinc finger protein 750)

2014-01-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
ZFP750
FUSION GENES

Other Information

Locus ID:

NCBI: 79755
MIM: 610226
HGNC: 25843
Ensembl: ENSG00000141579

Variants:

dbSNP: 79755
ClinVar: 79755
TCGA: ENSG00000141579
COSMIC: ZNF750

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141579ENST00000269394Q32MQ0
ENSG00000141579ENST00000572562I3L0W7

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
223648612012ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation.91
277498412016Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma.61
252286452014ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.46
229369862012ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes.12
305188682018m6A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression.12
182566912008A promoter sequence variant of ZNF750 is linked with familial psoriasis.11
221851982011Association analysis identifies ZNF750 regulatory variants in psoriasis.6
292166412018ZNF750 Expression Is a Potential Prognostic Biomarker in Esophageal Squamous Cell Carcinoma.6
285583822017ZNF750 Expression as a Novel Candidate Biomarker of Chemoradiosensitivity in Esophageal Squamous Cell Carcinoma.5
298904642018ZNF750 inhibited the malignant progression of oral squamous cell carcinoma by regulating tumor vascular microenvironment.4

Citation

Dessen P

ZNF750 (zinc finger protein 750)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53775/znf750