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ZNF85 (zinc finger protein 85)

Identity

Alias (NCBI)HPF4
HTF1
HGNC (Hugo) ZNF85
HGNC Alias symbHPF4
HTF1
HGNC Previous namezinc finger protein 85 (HPF4, HTF1)
LocusID (NCBI) 7639
Atlas_Id 43560
Location 19p12  [Link to chromosome band 19p12]
Location_base_pair Starts at 20923251 and ends at 20950697 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNF85   13160
Cards
Entrez_Gene (NCBI)ZNF85    zinc finger protein 85
AliasesHPF4; HTF1
GeneCards (Weizmann)ZNF85
Ensembl hg19 (Hinxton)ENSG00000105750 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105750 [Gene_View]  ENSG00000105750 [Sequence]  chr19:20923251-20950697 [Contig_View]  ZNF85 [Vega]
ICGC DataPortalENSG00000105750
TCGA cBioPortalZNF85
AceView (NCBI)ZNF85
Genatlas (Paris)ZNF85
SOURCE (Princeton)ZNF85
Genetics Home Reference (NIH)ZNF85
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF85  -     chr19:20923251-20950697 +  19p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF85  -     19p12   [Description]    (hg19-Feb_2009)
GoldenPathZNF85 - 19p12 [CytoView hg19]  ZNF85 - 19p12 [CytoView hg38]
ImmunoBaseENSG00000105750
Genome Data Viewer NCBIZNF85 [Mapview hg19]  
OMIM603899   
Gene and transcription
Genbank (Entrez)AI253261 AK308258 BC008688 BC036394 BC047646
RefSeq transcript (Entrez)NM_001256171 NM_001256172 NM_001256173 NM_003429
Consensus coding sequences : CCDS (NCBI)ZNF85
Gene ExpressionZNF85 [ NCBI-GEO ]   ZNF85 [ EBI - ARRAY_EXPRESS ]   ZNF85 [ SEEK ]   ZNF85 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF85 [ Firebrowse - Broad ]
GenevisibleExpression of ZNF85 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7639
GTEX Portal (Tissue expression)ZNF85
Human Protein AtlasENSG00000105750-ZNF85 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ03923   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ03923  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ03923
PhosPhoSitePlusQ03923
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    KRAB_dom_sf    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)ZNF85
SuperfamilyQ03923
AlphaFold pdb e-kbQ03923   
Human Protein Atlas [tissue]ENSG00000105750-ZNF85 [tissue]
HPRD04875
Protein Interaction databases
DIP (DOE-UCLA)Q03923
IntAct (EBI)Q03923
BioGRIDZNF85
STRING (EMBL)ZNF85
ZODIACZNF85
Ontologies - Pathways
QuickGOQ03923
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  nucleus  nucleoplasm  regulation of transcription, DNA-templated  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  nucleus  nucleoplasm  regulation of transcription, DNA-templated  metal ion binding  
NDEx NetworkZNF85
Atlas of Cancer Signalling NetworkZNF85
Wikipedia pathwaysZNF85
Orthology - Evolution
OrthoDB7639
GeneTree (enSembl)ENSG00000105750
Phylogenetic Trees/Animal Genes : TreeFamZNF85
Homologs : HomoloGeneZNF85
Homology/Alignments : Family Browser (UCSC)ZNF85
Gene fusions - Rearrangements
Fusion : QuiverZNF85
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF85 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF85
dbVarZNF85
ClinVarZNF85
MonarchZNF85
1000_GenomesZNF85 
Exome Variant ServerZNF85
GNOMAD BrowserENSG00000105750
Varsome BrowserZNF85
ACMGZNF85 variants
VarityQ03923
Genomic Variants (DGV)ZNF85 [DGVbeta]
DECIPHERZNF85 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF85 
Mutations
ICGC Data PortalZNF85 
TCGA Data PortalZNF85 
Broad Tumor PortalZNF85
OASIS PortalZNF85 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF85  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNF85
Mutations and Diseases : HGMDZNF85
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNF85
DgiDB (Drug Gene Interaction Database)ZNF85
DoCM (Curated mutations)ZNF85
CIViC (Clinical Interpretations of Variants in Cancer)ZNF85
Cancer3DZNF85
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603899   
Orphanet
DisGeNETZNF85
MedgenZNF85
Genetic Testing Registry ZNF85
NextProtQ03923 [Medical]
GENETestsZNF85
Target ValidationZNF85
Huge Navigator ZNF85 [HugePedia]
ClinGenZNF85
Clinical trials, drugs, therapy
MyCancerGenomeZNF85
Protein Interactions : CTDZNF85
Pharm GKB GenePA37733
PharosQ03923
Clinical trialZNF85
Miscellaneous
canSAR (ICR)ZNF85
HarmonizomeZNF85
ARCHS4ZNF85
DataMed IndexZNF85
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNF85
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 13:07:53 CET 2022

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