Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ZNRF1 (zinc and ring finger 1)

Identity

Alias (NCBI)NIN283
HGNC (Hugo) ZNRF1
HGNC Alias symbnin283
FLJ14846
DKFZp434E229
HGNC Previous namezinc and ring finger 1, E3 ubiquitin protein ligase
LocusID (NCBI) 84937
Atlas_Id 76470
Location 16q23.1  [Link to chromosome band 16q23]
Location_base_pair Starts at 74999024 and ends at 75110994 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZNRF1 (16q23.1) / BCAS4 (20q13.13)ZNRF1 (16q23.1) / ELMO1 (7p14.2)ZNRF1 (16q23.1) / SPATS2L (2q33.1)
ZNRF1 (16q23.1) / ZNRF1 (16q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ZNRF1   18452
Cards
Entrez_Gene (NCBI)ZNRF1    zinc and ring finger 1
AliasesNIN283
GeneCards (Weizmann)ZNRF1
Ensembl hg19 (Hinxton)ENSG00000186187 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186187 [Gene_View]  ENSG00000186187 [Sequence]  chr16:74999024-75110994 [Contig_View]  ZNRF1 [Vega]
ICGC DataPortalENSG00000186187
TCGA cBioPortalZNRF1
AceView (NCBI)ZNRF1
Genatlas (Paris)ZNRF1
SOURCE (Princeton)ZNRF1
Genetics Home Reference (NIH)ZNRF1
Genomic and cartography
GoldenPath hg38 (UCSC)ZNRF1  -     chr16:74999024-75110994 +  16q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNRF1  -     16q23.1   [Description]    (hg19-Feb_2009)
GoldenPathZNRF1 - 16q23.1 [CytoView hg19]  ZNRF1 - 16q23.1 [CytoView hg38]
ImmunoBaseENSG00000186187
Genome Data Viewer NCBIZNRF1 [Mapview hg19]  
OMIM612060   
Gene and transcription
Genbank (Entrez)AF378524 AK027752 AK094870 AK128349 AK294434
RefSeq transcript (Entrez)NM_032268
Consensus coding sequences : CCDS (NCBI)ZNRF1
Gene ExpressionZNRF1 [ NCBI-GEO ]   ZNRF1 [ EBI - ARRAY_EXPRESS ]   ZNRF1 [ SEEK ]   ZNRF1 [ MEM ]
Gene Expression Viewer (FireBrowse)ZNRF1 [ Firebrowse - Broad ]
GenevisibleExpression of ZNRF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84937
GTEX Portal (Tissue expression)ZNRF1
Human Protein AtlasENSG00000186187-ZNRF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8ND25   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8ND25  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8ND25
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8ND25
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-RING_2 (PF13639)   
Domain families : Pfam (NCBI)pfam13639   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)ZNRF1
PDB (RSDB)5YWR   
PDB Europe5YWR   
PDB (PDBSum)5YWR   
PDB (IMB)5YWR   
Structural Biology KnowledgeBase5YWR   
SCOP (Structural Classification of Proteins)5YWR   
CATH (Classification of proteins structures)5YWR   
SuperfamilyQ8ND25
AlphaFold pdb e-kbQ8ND25   
Human Protein Atlas [tissue]ENSG00000186187-ZNRF1 [tissue]
HPRD15893
Protein Interaction databases
DIP (DOE-UCLA)Q8ND25
IntAct (EBI)Q8ND25
BioGRIDZNRF1
STRING (EMBL)ZNRF1
ZODIACZNRF1
Ontologies - Pathways
QuickGOQ8ND25
Ontology : AmiGOprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  lysosome  endosome  cytosol  cytosol  membrane  synaptic vesicle membrane  proteasome-mediated ubiquitin-dependent protein catabolic process  metal ion binding  ubiquitin protein ligase activity  protein K48-linked ubiquitination  
Ontology : EGO-EBIprotein polyubiquitination  ubiquitin-protein transferase activity  protein binding  lysosome  endosome  cytosol  cytosol  membrane  synaptic vesicle membrane  proteasome-mediated ubiquitin-dependent protein catabolic process  metal ion binding  ubiquitin protein ligase activity  protein K48-linked ubiquitination  
NDEx NetworkZNRF1
Atlas of Cancer Signalling NetworkZNRF1
Wikipedia pathwaysZNRF1
Orthology - Evolution
OrthoDB84937
GeneTree (enSembl)ENSG00000186187
Phylogenetic Trees/Animal Genes : TreeFamZNRF1
Homologs : HomoloGeneZNRF1
Homology/Alignments : Family Browser (UCSC)ZNRF1
Gene fusions - Rearrangements
Fusion : QuiverZNRF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNRF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNRF1
dbVarZNRF1
ClinVarZNRF1
MonarchZNRF1
1000_GenomesZNRF1 
Exome Variant ServerZNRF1
GNOMAD BrowserENSG00000186187
Varsome BrowserZNRF1
ACMGZNRF1 variants
VarityQ8ND25
Genomic Variants (DGV)ZNRF1 [DGVbeta]
DECIPHERZNRF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNRF1 
Mutations
ICGC Data PortalZNRF1 
TCGA Data PortalZNRF1 
Broad Tumor PortalZNRF1
OASIS PortalZNRF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNRF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZNRF1
Mutations and Diseases : HGMDZNRF1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaZNRF1
DgiDB (Drug Gene Interaction Database)ZNRF1
DoCM (Curated mutations)ZNRF1
CIViC (Clinical Interpretations of Variants in Cancer)ZNRF1
Cancer3DZNRF1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612060   
Orphanet
DisGeNETZNRF1
MedgenZNRF1
Genetic Testing Registry ZNRF1
NextProtQ8ND25 [Medical]
GENETestsZNRF1
Target ValidationZNRF1
Huge Navigator ZNRF1 [HugePedia]
ClinGenZNRF1
Clinical trials, drugs, therapy
MyCancerGenomeZNRF1
Protein Interactions : CTDZNRF1
Pharm GKB GenePA134938288
PharosQ8ND25
Clinical trialZNRF1
Miscellaneous
canSAR (ICR)ZNRF1
HarmonizomeZNRF1
DataMed IndexZNRF1
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZNRF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:30:43 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.