ZP1 (zona pellucida glycoprotein 1)

2001-01-01  

Identity

HGNC
ZP1
LOCATION
11q12.2
LOCUSID
22917
ALIAS
HEL163,OOMD,OOMD1

Other Information

Locus ID:

NCBI: 22917
MIM: 195000
HGNC: 13187
Ensembl: ENSG00000149506

Variants:

dbSNP: 22917
ClinVar: 22917
TCGA: ENSG00000149506
COSMIC: ZP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149506ENST00000278853P60852
ENSG00000149506ENST00000278853V9HWI9
ENSG00000149506ENST00000540908H0YG11

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
ReproductionREACTOMER-HSA-1474165
FertilizationREACTOMER-HSA-1187000
Interaction With The Zona PellucidaREACTOMER-HSA-1300644

References

Pubmed IDYearTitleCitations
154616252004Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia.20
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
246701682014Mutant ZP1 in familial infertility.17
205048722010In humans, zona pellucida glycoprotein-1 binds to spermatozoa and induces acrosomal exocytosis.14
204069642010Risk of meningioma and common variation in genes related to innate immunity.12
180338062008Detection of zona pellucida proteins during human folliculogenesis.9
228894932012Genetic and physiological study of morphologically abnormal human zona pellucida.6
308108692019Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation.6
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.5
158604992005Association between sequence variations in genes encoding human zona pellucida glycoproteins and fertilization failure in IVF.4

Citation

Dessen P

ZP1 (zona pellucida glycoprotein 1)

Atlas Genet Cytogenet Oncol Haematol. 2001-01-01

Online version: http://atlasgeneticsoncology.org/gene/78457/zp1