ZPR1 (ZPR1 zinc finger)

2016-10-01  

Identity

HGNC
ZPR1
LOCATION
11q23.3
LOCUSID
8882
ALIAS
GKAF,ZNF259

Other Information

Locus ID:

NCBI: 8882
MIM: 603901
HGNC: 13051
Ensembl: ENSG00000109917

Variants:

dbSNP: 8882
ClinVar: 8882
TCGA: ENSG00000109917
COSMIC: ZPR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109917ENST00000227322O75312
ENSG00000109917ENST00000425791F8WBC5
ENSG00000109917ENST00000429220H7C0E5
ENSG00000109917ENST00000431973H7BZS1
ENSG00000109917ENST00000444935H7BZM7
ENSG00000109917ENST00000449430H7C449

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
204428572010Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.30
226239782012A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.28
170683322006Deficiency of the zinc finger protein ZPR1 causes defects in transcription and cell cycle progression.22
247800692014Association of the variants in the BUD13-ZNF259 genes and the risk of hyperlipidaemia.22
274118542016Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.21
249890722014Association between the MLX interacting protein-like, BUD13 homolog and zinc finger protein 259 gene polymorphisms and serum lipid levels.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
246883112014Sex-specific association of the zinc finger protein 259 rs2075290 polymorphism and serum lipid levels.11
206918292010Joint effects of common genetic variants from multiple genes and pathways on the risk of premature coronary artery disease.8

Citation

Dessen P

ZPR1 (ZPR1 zinc finger)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56312/zpr1