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ZRANB3 (zinc finger RANBP2-type containing 3)

Identity

Alias_nameszinc finger
Alias_symbol (synonym)DKFZP434B1727
Other alias4933425L19Rik
AH2
HGNC (Hugo) ZRANB3
LocusID (NCBI) 84083
Atlas_Id 52879
Location 2q21.3  [Link to chromosome band 2q21]
Location_base_pair Starts at 135196969 and ends at 135530730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DYNC1LI1 (3p22.3) / ZRANB3 (2q21.3)MCM6 (2q21.3) / ZRANB3 (2q21.3)RHOBTB1 (10q21.2) / ZRANB3 (2q21.3)
TSHZ2 (20q13.2) / ZRANB3 (2q21.3)ZRANB3 (2q21.3) / TMEM163 (2q21.3)ZRANB3 2q21.3 / TMEM163 2q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ZRANB3   25249
Cards
Entrez_Gene (NCBI)ZRANB3  84083  zinc finger RANBP2-type containing 3
Aliases4933425L19Rik; AH2
GeneCards (Weizmann)ZRANB3
Ensembl hg19 (Hinxton)ENSG00000121988 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121988 [Gene_View]  chr2:135196969-135530730 [Contig_View]  ZRANB3 [Vega]
ICGC DataPortalENSG00000121988
TCGA cBioPortalZRANB3
AceView (NCBI)ZRANB3
Genatlas (Paris)ZRANB3
WikiGenes84083
SOURCE (Princeton)ZRANB3
Genetics Home Reference (NIH)ZRANB3
Genomic and cartography
GoldenPath hg38 (UCSC)ZRANB3  -     chr2:135196969-135530730 -  2q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZRANB3  -     2q21.3   [Description]    (hg19-Feb_2009)
EnsemblZRANB3 - 2q21.3 [CytoView hg19]  ZRANB3 - 2q21.3 [CytoView hg38]
Mapping of homologs : NCBIZRANB3 [Mapview hg19]  ZRANB3 [Mapview hg38]
OMIM615655   
Gene and transcription
Genbank (Entrez)AI670931 AK095362 AK131303 AK304601 AL136824
RefSeq transcript (Entrez)NM_001286568 NM_001286569 NM_032143
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZRANB3
Cluster EST : UnigeneHs.658422 [ NCBI ]
CGAP (NCI)Hs.658422
Alternative Splicing GalleryENSG00000121988
Gene ExpressionZRANB3 [ NCBI-GEO ]   ZRANB3 [ EBI - ARRAY_EXPRESS ]   ZRANB3 [ SEEK ]   ZRANB3 [ MEM ]
Gene Expression Viewer (FireBrowse)ZRANB3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84083
GTEX Portal (Tissue expression)ZRANB3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5FWF4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5FWF4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5FWF4
Splice isoforms : SwissVarQ5FWF4
Catalytic activity : Enzyme3.6.4.- [ Enzyme-Expasy ]   3.6.4.-3.6.4.- [ IntEnz-EBI ]   3.6.4.- [ BRENDA ]   3.6.4.- [ KEGG ]   
PhosPhoSitePlusQ5FWF4
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)   
Domains : Interpro (EBI)Helicase_ATP-bd    Helicase_C    HNH    HNH_nuc    P-loop_NTPase    SNF2_N    Znf_RanBP2   
Domain families : Pfam (Sanger)Helicase_C (PF00271)    HNH (PF01844)    SNF2_N (PF00176)    zf-RanBP (PF00641)   
Domain families : Pfam (NCBI)pfam00271    pfam01844    pfam00176    pfam00641   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  HNHc (SM00507)  ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)ZRANB3
DMDM Disease mutations84083
Blocks (Seattle)ZRANB3
SuperfamilyQ5FWF4
Human Protein AtlasENSG00000121988
Peptide AtlasQ5FWF4
HPRD15896
IPIIPI00030279   IPI00796701   IPI00926904   IPI01013366   IPI01010070   IPI00878993   IPI00295888   
Protein Interaction databases
DIP (DOE-UCLA)Q5FWF4
IntAct (EBI)Q5FWF4
FunCoupENSG00000121988
BioGRIDZRANB3
STRING (EMBL)ZRANB3
ZODIACZRANB3
Ontologies - Pathways
QuickGOQ5FWF4
Ontology : AmiGODNA strand renaturation  DNA helicase activity  endodeoxyribonuclease activity  protein binding  ATP binding  nucleus  DNA repair  cellular response to DNA damage stimulus  zinc ion binding  response to UV  replication fork processing  DNA rewinding  annealing helicase activity  nuclear replication fork  negative regulation of DNA recombination  replication fork protection  K63-linked polyubiquitin binding  nucleic acid phosphodiester bond hydrolysis  
Ontology : EGO-EBIDNA strand renaturation  DNA helicase activity  endodeoxyribonuclease activity  protein binding  ATP binding  nucleus  DNA repair  cellular response to DNA damage stimulus  zinc ion binding  response to UV  replication fork processing  DNA rewinding  annealing helicase activity  nuclear replication fork  negative regulation of DNA recombination  replication fork protection  K63-linked polyubiquitin binding  nucleic acid phosphodiester bond hydrolysis  
NDEx NetworkZRANB3
Atlas of Cancer Signalling NetworkZRANB3
Wikipedia pathwaysZRANB3
Orthology - Evolution
OrthoDB84083
GeneTree (enSembl)ENSG00000121988
Phylogenetic Trees/Animal Genes : TreeFamZRANB3
HOVERGENQ5FWF4
HOGENOMQ5FWF4
Homologs : HomoloGeneZRANB3
Homology/Alignments : Family Browser (UCSC)ZRANB3
Gene fusions - Rearrangements
Fusion : MitelmanZRANB3/TMEM163 [2q21.3/2q21.3]  
Fusion: TCGAZRANB3 2q21.3 TMEM163 2q21.3 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZRANB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZRANB3
dbVarZRANB3
ClinVarZRANB3
1000_GenomesZRANB3 
Exome Variant ServerZRANB3
ExAC (Exome Aggregation Consortium)ZRANB3 (select the gene name)
Genetic variants : HAPMAP84083
Genomic Variants (DGV)ZRANB3 [DGVbeta]
DECIPHERZRANB3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZRANB3 
Mutations
ICGC Data PortalZRANB3 
TCGA Data PortalZRANB3 
Broad Tumor PortalZRANB3
OASIS PortalZRANB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZRANB3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZRANB3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZRANB3
DgiDB (Drug Gene Interaction Database)ZRANB3
DoCM (Curated mutations)ZRANB3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZRANB3 (select a term)
intoGenZRANB3
Cancer3DZRANB3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615655   
Orphanet
MedgenZRANB3
Genetic Testing Registry ZRANB3
NextProtQ5FWF4 [Medical]
TSGene84083
GENETestsZRANB3
Target ValidationZRANB3
Huge Navigator ZRANB3 [HugePedia]
snp3D : Map Gene to Disease84083
BioCentury BCIQZRANB3
ClinGenZRANB3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84083
Chemical/Pharm GKB GenePA134871612
Clinical trialZRANB3
Miscellaneous
canSAR (ICR)ZRANB3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZRANB3
EVEXZRANB3
GoPubMedZRANB3
iHOPZRANB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:04:00 CEST 2017

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