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ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2)

Identity

Alias_namesU2AF1L2
U2(RNU2) small nuclear RNA auxiliary factor 1-like 2
U2 small nuclear RNA auxiliary factor 1-like 2
Alias_symbol (synonym)U2AF1-RS2
URP
ZC3H22
Other aliasU2AF1RS2
HGNC (Hugo) ZRSR2
LocusID (NCBI) 8233
Atlas_Id 52759
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 15790451 and ends at 15823259 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ZRSR2 (Xp22.2) / CNTNAP2 (7q35)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Classification of myelodysplastic syndromes 2015


External links

Nomenclature
HGNC (Hugo)ZRSR2   23019
LRG (Locus Reference Genomic)LRG_618
Cards
Entrez_Gene (NCBI)ZRSR2  8233  zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
AliasesU2AF1-RS2; U2AF1L2; U2AF1RS2; URP; 
ZC3H22
GeneCards (Weizmann)ZRSR2
Ensembl hg19 (Hinxton)ENSG00000169249 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169249 [Gene_View]  chrX:15790451-15823259 [Contig_View]  ZRSR2 [Vega]
ICGC DataPortalENSG00000169249
TCGA cBioPortalZRSR2
AceView (NCBI)ZRSR2
Genatlas (Paris)ZRSR2
WikiGenes8233
SOURCE (Princeton)ZRSR2
Genetics Home Reference (NIH)ZRSR2
Genomic and cartography
GoldenPath hg38 (UCSC)ZRSR2  -     chrX:15790451-15823259 +  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZRSR2  -     Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblZRSR2 - Xp22.2 [CytoView hg19]  ZRSR2 - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIZRSR2 [Mapview hg19]  ZRSR2 [Mapview hg38]
OMIM300028   
Gene and transcription
Genbank (Entrez)AK090845 AK309673 BC050451 BC065719 BC113454
RefSeq transcript (Entrez)NM_005089
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZRSR2
Cluster EST : UnigeneHs.171909 [ NCBI ]
CGAP (NCI)Hs.171909
Alternative Splicing GalleryENSG00000169249
Gene ExpressionZRSR2 [ NCBI-GEO ]   ZRSR2 [ EBI - ARRAY_EXPRESS ]   ZRSR2 [ SEEK ]   ZRSR2 [ MEM ]
Gene Expression Viewer (FireBrowse)ZRSR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8233
GTEX Portal (Tissue expression)ZRSR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15696   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15696  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15696
Splice isoforms : SwissVarQ15696
PhosPhoSitePlusQ15696
Domaine pattern : Prosite (Expaxy)RRM (PS50102)    ZF_C3H1 (PS50103)   
Domains : Interpro (EBI)Nucleotide-bd_a/b_plait    RRM_dom    RRM_dom_euk    U2AF_small    Znf_CCCH   
Domain families : Pfam (Sanger)RRM_1 (PF00076)    zf-CCCH (PF00642)   
Domain families : Pfam (NCBI)pfam00076    pfam00642   
Domain families : Smart (EMBL)RRM_1 (SM00361)  ZnF_C3H1 (SM00356)  
Conserved Domain (NCBI)ZRSR2
DMDM Disease mutations8233
Blocks (Seattle)ZRSR2
SuperfamilyQ15696
Human Protein AtlasENSG00000169249
Peptide AtlasQ15696
HPRD02068
IPIIPI00018954   IPI00639872   
Protein Interaction databases
DIP (DOE-UCLA)Q15696
IntAct (EBI)Q15696
FunCoupENSG00000169249
BioGRIDZRSR2
STRING (EMBL)ZRSR2
ZODIACZRSR2
Ontologies - Pathways
QuickGOQ15696
Ontology : AmiGOspliceosomal complex assembly  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein binding  nucleoplasm  U12-type spliceosomal complex  RNA splicing  pre-mRNA 3'-splice site binding  metal ion binding  U2AF  
Ontology : EGO-EBIspliceosomal complex assembly  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein binding  nucleoplasm  U12-type spliceosomal complex  RNA splicing  pre-mRNA 3'-splice site binding  metal ion binding  U2AF  
NDEx NetworkZRSR2
Atlas of Cancer Signalling NetworkZRSR2
Wikipedia pathwaysZRSR2
Orthology - Evolution
OrthoDB8233
GeneTree (enSembl)ENSG00000169249
Phylogenetic Trees/Animal Genes : TreeFamZRSR2
HOVERGENQ15696
HOGENOMQ15696
Homologs : HomoloGeneZRSR2
Homology/Alignments : Family Browser (UCSC)ZRSR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZRSR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZRSR2
dbVarZRSR2
ClinVarZRSR2
1000_GenomesZRSR2 
Exome Variant ServerZRSR2
ExAC (Exome Aggregation Consortium)ZRSR2 (select the gene name)
Genetic variants : HAPMAP8233
Genomic Variants (DGV)ZRSR2 [DGVbeta]
DECIPHERZRSR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZRSR2 
Mutations
ICGC Data PortalZRSR2 
TCGA Data PortalZRSR2 
Broad Tumor PortalZRSR2
OASIS PortalZRSR2 [ Somatic mutations - Copy number]
Cancer Gene: CensusZRSR2 
Somatic Mutations in Cancer : COSMICZRSR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZRSR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch ZRSR2
DgiDB (Drug Gene Interaction Database)ZRSR2
DoCM (Curated mutations)ZRSR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZRSR2 (select a term)
intoGenZRSR2
Cancer3DZRSR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300028   
Orphanet
MedgenZRSR2
Genetic Testing Registry ZRSR2
NextProtQ15696 [Medical]
TSGene8233
GENETestsZRSR2
Target ValidationZRSR2
Huge Navigator ZRSR2 [HugePedia]
snp3D : Map Gene to Disease8233
BioCentury BCIQZRSR2
ClinGenZRSR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8233
Chemical/Pharm GKB GenePA162410930
Clinical trialZRSR2
Miscellaneous
canSAR (ICR)ZRSR2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZRSR2
EVEXZRSR2
GoPubMedZRSR2
iHOPZRSR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 13:04:01 CEST 2017

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