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ZSWIM4 (zinc finger SWIM-type containing 4)

Identity

Alias (NCBI)-
HGNC (Hugo) ZSWIM4
HGNC Alias symbFLJ12221
LocusID (NCBI) 65249
Atlas_Id 54821
Location 19p13.13  [Link to chromosome band 19p13]
Location_base_pair Starts at 13795443 and ends at 13832215 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ZNF699 (19p13.2) / ZSWIM4 (19p13.13)ZSWIM4 (19p13.13) / CCDC130 (19p13.2)ZSWIM4 (19p13.13) / FN3KRP (17q25.3)
ZSWIM4 (19p13.13) / MSMO1 (4q32.3)ZSWIM4 (19p13.13) / NDUFS4 (5q11.2)ZSWIM4 (19p13.13) / PLCB1 (20p12.3)
ZSWIM4 (19p13.13) / RFX1 (19p13.12)ZSWIM4 (19p13.13) / SLC1A6 (19p13.12)ZSWIM4 (19p13.13) / UBQLN4 (1q22)
ZNF699 19p13.2 / ZSWIM4 19p13.13ZSWIM4 19p13.13 / CCDC130 19p13.2ZSWIM4 19p13.13 / SLC1A6 19p13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(1;19)(q22;p13) ZSWIM4/UBQLN4
ZNF699/ZSWIM4 (19p13)
ZSWIM4/CCDC130 (19p13)
ZSWIM4/SLC1A6 (19p13)

External links

Nomenclature
HGNC (Hugo)ZSWIM4   25704
Cards
Entrez_Gene (NCBI)ZSWIM4    zinc finger SWIM-type containing 4
Aliases
GeneCards (Weizmann)ZSWIM4
Ensembl hg19 (Hinxton)ENSG00000132003 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132003 [Gene_View]  ENSG00000132003 [Sequence]  chr19:13795443-13832215 [Contig_View]  ZSWIM4 [Vega]
ICGC DataPortalENSG00000132003
TCGA cBioPortalZSWIM4
AceView (NCBI)ZSWIM4
Genatlas (Paris)ZSWIM4
SOURCE (Princeton)ZSWIM4
Genetics Home Reference (NIH)ZSWIM4
Genomic and cartography
GoldenPath hg38 (UCSC)ZSWIM4  -     chr19:13795443-13832215 +  19p13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZSWIM4  -     19p13.13   [Description]    (hg19-Feb_2009)
GoldenPathZSWIM4 - 19p13.13 [CytoView hg19]  ZSWIM4 - 19p13.13 [CytoView hg38]
ImmunoBaseENSG00000132003
genome Data Viewer NCBIZSWIM4 [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AK022283 AK024452 AK299057 BG764264
RefSeq transcript (Entrez)NM_001367834 NM_023072
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZSWIM4
Alternative Splicing GalleryENSG00000132003
Gene ExpressionZSWIM4 [ NCBI-GEO ]   ZSWIM4 [ EBI - ARRAY_EXPRESS ]   ZSWIM4 [ SEEK ]   ZSWIM4 [ MEM ]
Gene Expression Viewer (FireBrowse)ZSWIM4 [ Firebrowse - Broad ]
GenevisibleExpression of ZSWIM4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65249
GTEX Portal (Tissue expression)ZSWIM4
Human Protein AtlasENSG00000132003-ZSWIM4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H7M6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H7M6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H7M6
Splice isoforms : SwissVarQ9H7M6
PhosPhoSitePlusQ9H7M6
Domaine pattern : Prosite (Expaxy)ZF_SWIM (PS50966)   
Domains : Interpro (EBI)Znf_SWIM   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)ZSWIM4
Blocks (Seattle)ZSWIM4
SuperfamilyQ9H7M6
Human Protein Atlas [tissue]ENSG00000132003-ZSWIM4 [tissue]
Peptide AtlasQ9H7M6
HPRD15904
IPIIPI00303331   IPI00644135   
Protein Interaction databases
DIP (DOE-UCLA)Q9H7M6
IntAct (EBI)Q9H7M6
BioGRIDZSWIM4
STRING (EMBL)ZSWIM4
ZODIACZSWIM4
Ontologies - Pathways
QuickGOQ9H7M6
Ontology : AmiGOzinc ion binding  Cul2-RING ubiquitin ligase complex  regulation of axon guidance  
Ontology : EGO-EBIzinc ion binding  Cul2-RING ubiquitin ligase complex  regulation of axon guidance  
NDEx NetworkZSWIM4
Atlas of Cancer Signalling NetworkZSWIM4
Wikipedia pathwaysZSWIM4
Orthology - Evolution
OrthoDB65249
GeneTree (enSembl)ENSG00000132003
Phylogenetic Trees/Animal Genes : TreeFamZSWIM4
HOGENOMQ9H7M6
Homologs : HomoloGeneZSWIM4
Homology/Alignments : Family Browser (UCSC)ZSWIM4
Gene fusions - Rearrangements
Fusion : MitelmanZNF699/ZSWIM4 [19p13.2/19p13.13]  
Fusion : MitelmanZSWIM4/CCDC130 [19p13.13/19p13.2]  
Fusion : MitelmanZSWIM4/SLC1A6 [19p13.13/19p13.12]  
Fusion : MitelmanZSWIM4/UBQLN4 [19p13.13/1q22]  
Fusion PortalZNF699 19p13.2 ZSWIM4 19p13.13 BRCA
Fusion PortalZSWIM4 19p13.13 CCDC130 19p13.2 LUAD
Fusion PortalZSWIM4 19p13.13 SLC1A6 19p13.12 LUSC
Fusion : QuiverZSWIM4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZSWIM4 [hg38]
dbVarZSWIM4
ClinVarZSWIM4
MonarchZSWIM4
1000_GenomesZSWIM4 
Exome Variant ServerZSWIM4
GNOMAD BrowserENSG00000132003
Varsome BrowserZSWIM4
Genomic Variants (DGV)ZSWIM4 [DGVbeta]
DECIPHERZSWIM4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZSWIM4 
Mutations
ICGC Data PortalZSWIM4 
TCGA Data PortalZSWIM4 
Broad Tumor PortalZSWIM4
OASIS PortalZSWIM4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZSWIM4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DZSWIM4
Mutations and Diseases : HGMDZSWIM4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZSWIM4
DgiDB (Drug Gene Interaction Database)ZSWIM4
DoCM (Curated mutations)ZSWIM4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZSWIM4 (select a term)
intoGenZSWIM4
Cancer3DZSWIM4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETZSWIM4
MedgenZSWIM4
Genetic Testing Registry ZSWIM4
NextProtQ9H7M6 [Medical]
GENETestsZSWIM4
Target ValidationZSWIM4
Huge Navigator ZSWIM4 [HugePedia]
ClinGenZSWIM4
Clinical trials, drugs, therapy
MyCancerGenomeZSWIM4
Protein Interactions : CTD
Pharm GKB GenePA134975055
PharosQ9H7M6
Clinical trialZSWIM4
Miscellaneous
canSAR (ICR)ZSWIM4 (select the gene name)
HarmonizomeZSWIM4
DataMed IndexZSWIM4
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXZSWIM4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:45:36 CET 2021
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